Objective To understand the characteristics of death caused by diseases and injuries among residents in urban area of Shenyang City， provide a basis for formulating health prevention and control policies. Methods According to the ICD-10 code， the total cause of death database was classified， and the sex mortality rate， age mortality rate，standardized mortality， death composition ratio and related indicators of urban residents in Shenyang City in 2019 were calculated. The trend of mortality and life expectancy of urban residents in Shenyang City was analyzed from 2003-2019. Results In 2019， the crude mortality rate of Shenyang urban residents was 904.75/lakh （1 056.75/lakh for male， 760.59/lakh for female）， and the standardized mortality rate was 337.13/lakh（409.08/lakh for male， 270.49/lakh for female）. The crude mortality rate of infant was 0.215%（0.276% for male, 0.149% for female）， and neonatal deaths accounted for 63.64% of infant deaths. In 2019， the crude mortality rate of urban residents increased with age（X²=201 771.752， P<0.05）. The crude mortality rate and standardized mortality rate of males were higher than those of females. From 2003-2019， the crude mortality rate of urban residents increased with the change of years （X²=4 416.183， P<0.05）， while the standardized mortality rate showed downward trend（X²=148.285， P<0.05）. In 2019 the chronic non-communicable diseases were the leading cause of death among Shenyang urban residents，accounting for 82.65% of all deaths. The top three causes of death in sequence were heart disease， tumor and cerebrovascular disease， and the top five deaths of malignant tumors were lung cancer， colorectal cancer， liver cancer， stomach cancer and breast cancer. From 2013-2019， the life expectancy of Shenyang urban residents was generally on the rise，and the life expectancy in 2019 was 80.85 years. Conclusio Chronic non-communicable diseases seriously threaten the lives and health of Shenyang urban residents. Shenyang City should continue to carry out in-depth interventions on risk factors for chronic disease behaviors，advocate healthy lifestyles， solidly promote five cancer screenings， and strengthen the targeted prevention and control of children， men， pregnant women and the elderly.

Cause of death, Mortality rate, Change trend