Abstract: Objective To understand the status knowledge,behavior characteristics and prevalence of human immunodeficiency virus（HIV） infection among female sex workers in Chongming district of Shanghai,and provide reference data for the development of acquired immunodeficiency syndrome（AIDS） prevention and control strategies. Methods Women engaged in commercial sex trade in entertainment venues in Chongming District of Shanghai from 2018 to 2021 were selected as the research subjects. A questionnaire survey was conducted for female sex workers,and blood samples were collected for HIV,syphilis and HCV antibody testing. Results A total of 1 600 subjects were monitored from 2018 to 2021,with an age of（38.4±8.39）years old.The awareness rates of AIDS prevention and control over the years were 94.5%,95.75%,97.50% and 98.50%,showing an upward trend,with statistical significance（χ²=11.505,P<0.05）. The total condom use rate of the last commercial sex was 92.19%,and the previous years were 93.5%,99%,90.5% and 85.75%,respectively,with statistical significance（χ²=51.33,P<0.05）. The total positive rate of HIV antibody was 0,the total positive rate of syphilis was 1.5%,and the total positive rate of HCV was 0.8%. Conclusion There is no HIV positive among the female sex workers in Chongming District of Shanghai,and the knowledge rate of AIDS prevention and treatment is relatively high. However,the proportion of insisting on using condoms needs to be improved and new intervention models should be explored to expand the coverage of intervention and testing,aiming to improve the self-protection awareness of female sex workers.

Key words: Human immunodeficiency virus, Sentinel surveillance, Female sex workers