Dynamic observation of blood indexes of radiologists in Shenyang City

Abstract

Abstract: Objective To discuss the effects of ionizing radiation on peripheral blood,biochemical indexes,lymphocyte micronucleus and chromosome of radiologists. Methods A total of 137 radiologists who underwent four consecutive occupational health examinations in 2014,2016,2018 and 2020 were selected as the radiation group,and 137 health examiners of the same age and sex with no radiation exposure history were selected as the control group. Their peripheral blood white blood cells（WBC）,lymphocytes（LYM）,platelets（PLT）,alanineaminotransferase（ALT）,aspartate aminotransferase（AST）,blood urea nitrogen（BUN）,serum creatinine（Scr）,fasting blood glucose（FBG）,lymphocyte micronucleus and chromosomal examination results were analyzed. Results The WBC count of radiation group in 2020（6.15±1.42）,2018（6.26±1.38） and 2016（6.13±1.36） was lower than that of control group（6.59±1.18）（all P<0.05）. The PLT count of radiation group in 2018（223.39±50.18）,2016（221.68±49.82） and 2014（228.53±49.95） was lower than that of control group（242.47±54.39）（all P<0.05）. The micronucleus rate of lymphocytes in radiation group in 2018[（0.66±0.90）‰] and 2016[（1.17±1.25）‰] was higher than that in control group[（0.41±0.77）‰],and the differences were statistically significant（all P<0.05）. The number of chromosomal abnormalities in radiologists working in the same compartment was higher than that in those working in the other compartment,and the difference between 2020 and 2018 was statistically significant（P<0.05）. Conclusion The ionizing radiation has a certain effect on the blood indexes of radiologists,so it is necessary to strengthen the continuous monitoring of the chromosome of radiologists working in the same compartment.

Key words: Radiologists, Continuous monitoring, Blood indexes

CLC Number:

R146

SHAN Tie-mei, DUAN Xiao-xiao, NA Xiang-jie. Dynamic observation of blood indexes of radiologists in Shenyang City. [J]OCCUPATION AND HEALTH, 2023, 39(11): 1460-1463.

References

[1] 陈正齐,姚洪章,刘定理,等.低剂量电离辐射对放射工作人员健康影响的调查[J].中国辐射卫生,2005,14(2):124-125.
[2] 中华人民共和国国家卫生和计划生育委员会.放射工作人员健康要求:GBZ 98—2017[S].北京:人民卫生出版社,2017:3.
[3] 吕玉民.染色体畸变在急慢性辐射损伤评估中的意义专家解析[J].中国辐射卫生,2019,28(4):349-353.
[4] 中华人民共和国国家卫生和计划生育委员会.放射工作人员健康要求:GBZ 98—2017[S],北京:中国标准出版社,2017:4.
[5] 白玉书,陈德清.人类辐射细胞遗传学[M].北京:人民卫生出版社,2006:110.
[6] 中华人民共和国国家卫生和计划生育委员会放射工作人员职业健康检查外周血淋巴细胞染色体畸变检测与评价:GBZ/T 248—2014[S]华人民共和国国家卫生和计划生育委员会放射工作人员职业健康检查外周血淋巴细胞染色体畸变检测与评价:GBZ/T 248—2014[S].北京:中国标准出版社,2014:4.
[7] 李举跃,陈小霞.刘红卫.2013—2015年濮阳市放射工作人员个人剂量监测结果分析[J].工业卫生与职业病,2017,43(3):220-224.
[8] 冀琛,焦志娟,徐大勇,等.北京市丰台区2012年放射工作人员个人剂量监测结果[J].职业与健康,2014,30(7):893—894.
[9] 迟欣,陈超,嵇平钟,等.2014年烟台市放射工作人员个人剂量监测结果分析[J].中华放射医学与防护杂志,2015,35(8):621-622.
[10] 王莉莉,宁丽,刘继文.放射工作人员免疫球蛋白含量、淋巴细胞染色体畸变及微核检测结果分析[J].职业与健康,2020,36(2):235-237.
[11] 杨非,周敏,龚力,等.低剂量电离辐射对放射从业者血小板及白细胞的影响分析[J].中华流行病学杂志,2016,37(12):1578-1582.
[12] 许培,金武,毛一扬,等.扬州市放射工作人员外周血淋巴细胞微核细胞率分析[J].职业卫生与应急救援,2020,38(1):44-46.
[13] 张学清,陈英,王治东,等.健康成人自发染色体畸变率与微核率的本底状况再分析[J].癌变·畸变·突变,2014,26(1):56-58.
[14] 周丽丽,迟江朋,左太,等.某轧钢厂放射工作人员静脉血细胞分析[J].工业卫生与职业病,2012,38(2):107.
[15] 王珂,王潇,王惠萱,等.低剂量电离辐射对作业人员外周血淋巴细胞亚群的影响[J].国际检验医学杂志,2012,33(20):2515-2517.
[16] 妥娅,赵永成.低剂量电离辐射对放射工作人员肝功能的影响[J].基础医学与临床,2017,37(12):1738-1740.
[17] 娄淑艳,张钦富,李洁雅.放射工作人员外周血象近十年前后结果分析[J].中国辐射卫生,2007,16(4):438.
[18] 曹毅,谢文.电离辐射的生物效应及健康影响[J].科技导报,2018,36(15):48-53.
[19] 蔡露,刘树铮.低剂量辐射诱发的细胞遗传学适应性反应[J].中华放射医学与防护杂志,1990,10(1):55-59.
[20] ESPOSITO G,CAMPA A,PINTO M,et al.Adaptive response:Modelling and experimental studies[J].Radiat Prot Dosimetry,2011,143(2/3/4):320-324.
[21] 中华人民共和国全国人民代表大会常务委员会.中华人民共和国职业病防治法[S].北京:法律出版社,2012:5-8.
[22] 刘征宇,杨学琴,惠长野,等.深圳市放射工作人员周围血淋巴细胞染色体畸变分析[J].职业与健康,2013,29(13):1549-1551.
[23] 张伟佳,张雨,师依婷,等.2016—2017年介入放射学工作人员职业性外照射个人剂量水平调查分析[J].中国辐射卫生,2019,28(1):55-58.
[24] 桑军阳,谭维维,钟恩德,等.2009—2017年南通市某三甲综合医院介入放射工作人员个人剂量和工作场所监测结果分析[J].中国辐射卫生,2019,28(3):309-312.
[25] 刘长安.放射工作人员职业健康监护[M].北京:原子能出版社,2004:85.