Abstract: Objective To understand the status of infectious disease health literacy,occupational stress,and occupational burnout among infection department nurses in four grade-A tertiary hospitals in Shanghai,and to explore the mediating role of infectious disease health literacy. Methods Convenient sampling method was used to select 206 nurses from the infectious disease department of 4 grade-A tertiary hospitals in Shanghai City from June to September 2023 as the survey subjects. The survey was conducted using a general situation questionnaire,infectious disease health literacy scale,occupational stress scale,and occupational burnout scale,and the data were analyzed. Results The infectious disease health literacy score of nurses in the infection department was （24.42±3.16）points,occupational stress score was （88.67±11.32）points,and occupational burnout score was （60.62±12.81）points. Univariate analysis showed that infectious disease health literacy among infection department nurses was related to age,length of service,educational level,professional title,monthly income,and monthly night shifts（all P<0.05）,occupational stress was related to age,length of service,professional title,monthly income,and monthly night shifts（all P<0.05）,and occupational burnout was related to age,length of service,professional title,marital status,monthly income,and monthly night shifts（all P<0.05）. The occupational burnout of infection department nurses was negatively correlated with infectious disease health literacy（r=-0.524,P<0.01）,and positively correlated with occupational stress（r=0.628,P<0.01）. The occupational stress of infection department nurses was negatively correlated with infectious disease health literacy（r=-0.576,P<0.01）. The infectious disease health literacy of infectious disease nurses played a partial mediating effect between occupational stress and occupational burnout,with a mediating effect of 0.268,accounting for 48.90% of the total effect. Conclusion The infectious disease health literacy of infection department nurses plays a partial mediating role between occupational stress and occupational burnout. Nursing managers should pay attention to and improve the level of infectious disease health literacy of infection department nurses,in order to alleviate their occupational stress and reduce their occupational burnout level.

Key words: Infection department nurse, Infectious disease health literacy, Occupational stress, Occupational burnout, Mediation