Abstract: Objective To understand the occupational protection knowledge,attitude and practice of novel coronavirus infection before and after undergraduate nursing students' internships,and to provide reference for undergraduate nursing colleges,internship hospitals and relevant departments to improve the training model of undergraduate nursing talents. Methods The undergraduate nursing students of grade 2017 in the School of Nursing of Guangzhou University of Chinese Medicine,who completed a 10-month internship in the hospital in April 2021,were the pre-internship research object and the undergraduate nursing students of grade 2018,who began a 10-month internship in the hospital in July 2021,were the post-internship research object,whome were selected to investigate the knowledge,attitude and practice of novel coronavirus infection occupational protection before and after the internship. Results The 133 people were investigated before the internship and 127 people after the internship. The pre-internship knowledge questionnaire score was （6.93±3.19）points,and the post-internship knowledge questionnaire score was （9.23±1.31）points;the pre-internship attitude questionnaire score was （41.66±5.47）points,and the post-internship attitude questionnaire score was （47.46±4.45）;the pre-internship practice questionnaire score was （43.79±7.13）points,and the post-internship practice questionnaire score was（48.74±4.19）points. The results of multiple linear regression analysis showed that the common influencing factors of the occupational protection knowledge,attitude and practice of novel coronavirus infection of nursing students before internship were the grade of probation hospitaland and type of probation hospital,whether or not having accepted novel coronavirus infection 's occupational protection operation examination was also the influencing factor of knowledge（all P<0.05）. The influencing factors of novel coronavirus infection's occupational protection knowledge of nursing students after internship were the type of probation hospital and the number of ampule cuts,the number of ampule cuts was also an influencing factor of attitude（all P<0.05）. Conclusion The administrative department of health should establish and improve the occupational protection regulations and laws and regulations for medical staff,educational administrative department should add occupational safety courses and emergency ability training courses to the undergraduate nursing curriculum system and standards,and the practice hospital should strengthen the pre-job training and internship assessment of occupational protection for nursing students.Vocational safety education should be infiltrated into the teaching of all professional courses in nursing colleges. Undergraduate nursing students should conscientiously study the knowledge and skills of occupational protection and enhance the ability of occupational stress resistance.

Key words: Undergraduate nursing student, Novel coronavirus infection, Occupational protection, Knowledge, Attitude/Belief, Practice