Meta-analysis of traditional Chinese medicine in the treatment of pneumoconiosis

Abstract

Abstract: Objective To understand the therapeutic effect of traditional Chinese medicine on pneumoconiosis. Methods Literature on the treatment of pneumoconiosis with traditional Chinese medicine published in domestic and foreign medical journals from December 2000 to June 2022 was retrieved. The experimental group was treated with traditional Chinese medicine alone or with traditional Chinese medicine combined with western medicine,and the control group was treated with western medicine or placebo or no treatment. Totally 17 literatures were included,including 1 424 cases of pneumoconiosis,and meta-analysis was performed with Review Manager 5.4. Results Compared with the control group,Chinese medicine treatment can improve the clinical treatment efficiency of patients（OR=6.51,95%CI：3.36-12.64）,improve clinical respiratory symptoms（OR=3.29,95%CI：2.50-4.31）, significantly improve the shadow of infected lung（OR=9.75,95%CI：4.89-19.45）,improve pulmonary function FEV1（OR=0.98, 95%CI：0.43-1.54）,FEV1/FVC（OR=6.82,95%CI：4.90-8.74） and FEV1%（OR=8.66,95%CI：6.57-10.75）,and significantly increase 6MWT（OR=45.71,95%CI：27.21-64.21）,the differences were statistically significance（all P<0.05）. Conclusion Traditional Chinese medicine in the treatment of pneumoconiosis has certain advantages in improving the clinical treatment efficiency,improving clinical symptoms and infected lung shadows,improving lung function and increasing 6MWT. However,due to the small sample size of the included studies,more high-quality studies are needed to verify.

Key words: Traditional Chinese medicine, Pneumoconiosis, Treatment, System assessment

CLC Number:

R181.2

LI Shiting, DONG Diewen, ZHENG Xinliang, CUI Lin, ZHANG Min. Meta-analysis of traditional Chinese medicine in the treatment of pneumoconiosis. [J]OCCUPATION AND HEALTH, 2024, 40(5): 689-692.

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