Research progress on the effects of artificial sweeteners on human health

Abstract

Abstract: Artificial sweeteners（ASs） is a class of artificially synthesized or semi synthetic organic compounds widely used in the production of food,condiments,beverages,health foods,and pharmaceuticals,which can be added in small amounts to give food or medicine a sweet taste. Due to its low price,high sweetness,high stability,good water solubility,and good palatability,ASs has been widely used as a food additive in food or pharmaceutical production and processing in recent years. So far,the safety of ASs has been highly controversial,closely related to food safety and the physical health of the people. Therefore,studying the impact of ASs on health is of great significance and value. This article provides a review of the current usage status of ASs,and the research progress of its impact on various organ systems and physiological metabolism on the human body. It mainly introduces the effects of ASs on the nervous system,endocrine system,gut microbiota,circulatory system,reproductive system,and immune system,as well as its reproductive toxicity,genetic toxicity and carcinogenic effects,aiming to enhance the comprehensive understanding and knowledge of ASs on the people and provide reference basis for the selection of daily food and drugs for residents.

Key words: Artificial Sweeteners, Non-nutritive sweeteners, Food safety, Health impact

CLC Number:

R151.3

SUN Wei, LU Jingjing, LYU Meng, PAN Shenyi, CHEN Fanyu, JIANG Apei. Research progress on the effects of artificial sweeteners on human health. [J]OCCUPATION AND HEALTH, 2024, 40(16): 2299-2304.

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