Abstract: Objective To analyze the epidemic characteristics and change trends of varicella in children aged 0-14 years old in Changsha City from 2010 to 2022,provide the basis of formulating strategies for varicella prevention and control in children. Methods The varicella surveillance data of children aged 0-14 years old in Changsha City from 2010 to 2022 were collected from the Chinese Disease Prevention and Control Information System,and the data were analyzed. Results From 2010 to 2022,the annual average incidence rate of varicella in children aged 0-14 years old was 440.07/100 000. The overall reported incidence rate showed a trend of first rising,then declining. From 2010 to 2018,it showed an upward trend（APC=13.1%,P<0.05）,and from 2018 to 2022,it showed a downward trend（APC=-30.1%,P<0.05）. The incidence rate of boys was higher than that of girls,and the change trend of boys and girls was similar to that of all children. The cases of varicella were mainly children aged 3-<10 years old. The reported incidence rate of varicella in children aged 6-<10 years old was generally declining（AAPC=-8.2%,P<0.05）. The annual average reported incidence rate of varicella in children aged <3,3-<6 and 10-14 years old had a significant change. The varicella incidence rate among children in urban area showed a downward trend（AAPC=-10.2%,P<0.05）,but there was no significant change in the incidence of varicella in children in county（city）. Conclusions The incidence of varicella in children in Changsha City shows a trend of first increasing and then decreasing,and children aged 3-<10 years old are the high incidence group of varicella. It is recommended to strengthen the monitoring and management of schools and kindergartens,improve health education,and incorporate varicella vaccine into routine immunization as soon as possible.

Key words: Varicella, Epidemiology, Trend analysis, Children