Analysis of polyphenolic compounds in Forsythia suspense leaves from different producing areas in Qinba Mountain Areas

OCCUPATION AND HEALTH ›› 2023, Vol. 39 ›› Issue (15): 2017-2020.

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Analysis of polyphenolic compounds in Forsythia suspense leaves from different producing areas in Qinba Mountain Areas

LUO Xia¹, ZHAO Lijun¹, ZHU Yu^1,2, WEI Juan^1,2, ZHOU Can¹, ZHANG Xiaoyan¹

1. Department of Pharmacy,Shiyan People's Hospital,People's Hospital Affiliated to Hubei University of Medicine,Shiyan Hubei 442000,China;
2. Hubei Key Laboratory of Wudang Local Chinese Medicine Research,Shiyan Hubei 442000,China

Received:2023-01-19 Revised:2023-02-20 Published:2026-03-24
Contact: ZHANG Xiaoyan,Chief pharmacist,E-mail：530011759@qq.com

Abstract

Abstract: Objective To determine the content of polyphenols in the Forsythia suspense leaves from different producing areas in Qinba Mountain Areas,evaluate the quality of Forsythia suspense leaves. Methods The HPLC was used to measure the content of forsythin,forsythiaside A and rutin,UV-Vis spectrophotometry was used to determine the content of total flavonoids. Based on the contents of above four components in 10 batches of Forsythia suspense leaves from different producing areas in Qinba Mountain Areas,TOPSIS method was used to evaluate the overall quality of Forsythia suspense leaves. Results The TOPSIS analysis results showed that the relative closeness of 10 batches of Forsythia suspense leaves from different producing areas were 0.421 6,0.328 1, 0.432 3,0.275 9,0.268 8,0.824 1,0.384 1,0.779 3,0.464 8 and 0.779 4,respectively. The top three samples in the quality evaluation were collected from Hualong Town of Fangxian County,Guihua Village of Majiadu in Zhushan County and Qingshi Villag of Huanglong Town in Zhangwan District. Conclusion The contents of three kinds of polyphenols compounds in Forsythia suspense leaves from all producing areas in Qinba Mountain Areas meet the requirements of the 2015 edition of Chinese Pharmacopoeia,which provides a theoretical basis for its rational development and utilization.

Key words: Forsythia suspense leaves, HPLC, Polyphenolic compounds, UV-Vis spectrophotometry, TOPSIS method

CLC Number:

：R115

LUO Xia, ZHAO Lijun, ZHU Yu, WEI Juan, ZHOU Can, ZHANG Xiaoyan. Analysis of polyphenolic compounds in Forsythia suspense leaves from different producing areas in Qinba Mountain Areas. [J]OCCUPATION AND HEALTH, 2023, 39(15): 2017-2020.

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Analysis of polyphenolic compounds in Forsythia suspense leaves from different producing areas in Qinba Mountain Areas

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