Effect of sea cucumber taurine capsule on immune function of mice

Abstract

Abstract: Objective To investigate the immune function of sea cucumber taurine capsules. Methods The effects of sea cucumber taurine capsules on immunity of mice were investigated by delayed allergic reaction,spleen lymphocyte transformation,half haemolysis value,antibody-producing cell test,carbon profiling test and peritoneal macrophagy of chicken red blood cells. Results The concanavalin A（ConA）-induced proliferation of spleen T lymphocytes was promoted by high dose sea cucumber taurine capsules,which was 0.248±0.034 in the high dose group and 0.198±0.026 in the control group,and the difference was statistically significant（P<0.05）.The values of planta swelling in the middle and high dose groups was （0.74±0.23） and （0.74±0.17）mm respectively,which was statistically significant compared with the control group[（0.48±0.16）mm]（P<0.05）. The half hemolytic value in the high dose group（278.3±16.2） was higher than that in the control group（247.4±12.4）,and number of antibody producing cells in the middle dose group[（33.4±4.9）×10³cells] was higher than that in the control group[（28.1±3.8）×10³cells]（P<0.05）. Conclusion The sea cucumber taurine capsule can improve the immune function of mice.

Key words: Sea cucumber taurine capsule, Immune function, Mice

CLC Number:

R-332

LIU Yinghua, ZHANG Shujing, ZHANG Jing, ZHOU Dianming, ZHOU Qinghong, QIAN Zhiyong. Effect of sea cucumber taurine capsule on immune function of mice. [J]OCCUPATION AND HEALTH, 2023, 39(18): 2490-2493.

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