Abstract: Objective To analyze the mortality level and disease burden trend of chronic obstructive pulmonary disease（COPD） in Dandong from 2011 to 2021. Methods The monitoring data on COPD mortality in Dandong were used to calculate the trends of index such as crude mortality,standardized mortality,premature death probability,years of life lost（YLL）,and average years of life lost（AYLL）. The Chi-squared test was used to compare the rates and JoinPoint 4.9.1 software was used to analyze the annual percent of change（APC）. Results From 2011 to 2021,the crude mortality rate of COPD in Dandong was 20.25/100 000,the standardized mortality rate was 16.79/100 000,the premature death probability was 0.25%,the YLL rate was 100.87/100 000,the standardized YLL rate was 83.72/100 000,the AYLL rate was 4.98 years per person,and the standardized AYLL was 4.99 years per person. The standardized mortality rate of COPD showed a decreasing trend（APC=-6.18%,P<0.01）. The probability of premature death showed a decreasing trend（APC=-7.94%,P<0.01）. The standardized mortality rate and probability of premature death in males were higher than those in females,with statistically significant differences（both P<0.05）. The standardized YLL rate decreased from 83.72/100 000 in 2011 to 47.74/100 000 in 2021,with the APC being -7.64%（P<0.01）. The standardized AYLL decreased from 5.56 years per person in 2011 to 4.83 years per person in 2021,with the APC being-7.61%（P<0.05）. Conclusion From 2011 to 2021,the mortality rate and life loss of COPD in Dandong City showed a downward trend,but the disease burden was still at a high level. Male residents should be focused on to strengthen the comprehensive prevention and treatment of COPD.

Key words: Chronic obstructive pulmonary disease, Probability of premature death, Disease burden