Abstract:

Objective To explore the influencing factors of micronucleus levels in peripheral blood lymphocytes of medical radiation workers. Methods A total of 716 radiation workers who participated in occupational health examinations at the Hubei Provincial Center for Disease Control and Prevention in 2023 were selected as the research subjects. Among them，536 workers who underwent occupational health examinations during their employment were the exposed group，while 180 workers who underwent pre-employment occupational health examinations at the same institution in the same year were the control group. Descriptive analysis，univariate analysis，and multivariate Poisson regression were used to analyze the micronucleus examination results and influencing factors of medical radiation workers. Results Compared among different job types，the annual effective dose[M（P₂₅，P₇₅）] of the nuclear medicine group was the highest[0.22（0.11，0.38）mSv]，followed by the interventional radiology group[0.13（0.06，0.22）mSv]，with statistically significant differences between groups（P<0.05）. Compared with different exposure durations， the annual effective dose of the group with an exposure duration of 1-<5 years was the highest[0.13（0.07，0.20）mSv]，and the group with an exposure duration of ≥20 years was the lowest，with statistically significant differences between groups（P<0.05）. The micronucleus rate and micronucleus detection rate in the exposed group were higher than those in the control group，and the differences were statistically significant（both P<0.05）. The micronucleus rate and micronucleus detection rate in the exposed group were positively correlated with age（both P<0.05）. The micronucleus rate and micronucleus detection rate in the exposed group were higher in females than in males（both P<0.05）. The micronucleus rate and micronucleus detection rate in the interventional diagnosis group were significantly higher than those in the control group（both P<0.05）. Conclusion Gender，age，and job type are influencing factors on the micronucleus rate and micronucleus detection rate of radiation workers. It is necessary to strengthen radiation protection for senior，female，and interventional radiation workers.

Key words: Ionizing radiation, Medical applied radiology workers, Effective dose, Peripheral blood lymphocyte micronuclei