Analysis of the main parameters of blood cell counts of 5 870 cases of radiation workers in Guizhou Province in 2023

Abstract

Abstract: Objective To investigate the effects of low-dose ionizing radiation on the main blood count parameters of radiation workers,and provide reference basis for health monitoring and risk assessment of radiation workers. Methods The results of blood cell counts of 5 870 radiation workers who underwent occupational health examination in Guizhou Province in 2023 were statistically analyzed according to different ages,different years of exposure to hazards,and different types of work. Results The platelet count（PLT） of the exposed group[（240.06±59.09）×10⁹/L] was significantly higher than that of the control group[（236.36±58.01）×10⁹/L],with a statistically significant difference（P<0.05）. The mean platelet volume（MPV） in the exposed group was（11.04±1.48）fl,compared to （10.88±1.42）fl in the control group,with a statistically significant difference（P<0.05）. The platelet crit（PCT） in the exposed group was （0.26±0.05）%,versus （0.25±0.05）% in the control group,showing a statistically significant difference（P<0.05）. The platelet distribution width（PDW） in the exposed group was （15.35±2.19）fl,while it was （15.20±2.35）fl in the control group,with a statistically significant difference（P<0.05）. The platelet large cell ratio（P-LCR） in the exposed group was （33.21±9.99）%,compared to （32.06±9.63）% in the control group,also showing a statistically significant difference（P<0.05）. The red blood cell count（RBC） of males in the exposed group was （5.40±0.45）×10¹²/L,while in the exposed group it was （5.34±0.48）×10¹²/L,with a statistically significant difference（P<0.05）. However,there were no statistically significant differences in white blood cell count（WBC）,hemoglobin（HB）,and female RBC count between the two groups（all P>0.05）. As the length of service increased,WBC count,MPV,and P-LCR showed an upward trend. Compared with the pre-post group,there were statistically significant differences between the 0-<10,10-<20,and ≥30 year groups（all P<0.05）. PCT,PLT counts,and RBC counts decreased progressively with increasing years of service,and the differences between the groups were statistically significant（all P<0.05）. Analysis among different types of work revealed that WBC count,PLT,MPV,PCT,PDW,and P-LCR were decreased in the radiation therapy group,interventional radiology group,and dental radiology group compared with the diagnostic radiology group（all P<0.05）. Compared with the radiation therapy group,PLT,MPV,P-LCR,and male RBC counts were all reduced in the interventional radiology group and the dental radiology group,MPV and P-LCR were reduced in the nuclear medicine group（all P<0.05）. Compared with the interventional radiology group,the dental radiology group showed a statistically significant decrease in male RBC counts（P<0.05）. Conclusion Prolonged exposure to low doses of radiation causes changes in blood cell counts WBC, MPV,PCT,PDW,P-LCR,RBC. When conducting health monitoring for radiation workers,attention should be paid to changes in such indicators to further improve their occupational health.

Key words: Ionizing radiation, Radiation workers, Blood routine, Low dose, Parameter analysis, Guizhou Province

CLC Number:

R148

CHEN Youhong, LI Zuoxiang, LI Ling, LI Yi, HOU Teng. Analysis of the main parameters of blood cell counts of 5 870 cases of radiation workers in Guizhou Province in 2023. [J]OCCUPATION AND HEALTH, 2024, 40(23): 3175-3178.

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