Abstract: Objective To explore the level of negative emotions and hypochondriac state among medical college students,and the intervention effect by single guided imagery and music（GIM） on hypochondriac state. Methods In May 2022,196 current college students were selected from a medical university in Guangzhou,the psychological questionnaire for emergent events of public health（PQEEPH） and the Minnesota multiphasic personality inventory-hypochondriasis subscale（MMPI-Hs） were used to measure their negative emotions（including five dimensions：depression,neurasthenia,horror,compulsiveness-anxiety and hypochondriasis） and hypochondriasis level. 30 participants were selected based on MMPI-Hs scores to use GIM techniques for a single intervention. Results The levels of negative emotions and hypochondriac state of medical college students were relatively low. The mean values of 5 dimensions measure by PQEEPH were all <1 point,and the hypochondriasis T score measure by MMPI-Hs was （49.47±9.32）points. Medical students had higher scores in compulsiveness-anxiety[（0.36±0.45）points]. The scores of compulsive anxiety[（0.36±0.45）point] and hypochondria[（50.85±9.42）points] among medical students were higher than those of non medical students[（0.25±0.32）,（48.03±9.03）points],and the differences were statistically significant（P<0.05）. The single GIM intervention reduced negative emotions,with result showing a significant decreasing trend of horror scores after intervention[（0.64±0.51）points] compared with non-intervention[（0.79±0.54）points],but the difference was not statistically significant（P>0.05）. Intervention of the single GIM on hypochondriac state of medical students was significant,and the difference before and after intervention was statistically significant（P<0.05）. Intervention of the single GIM on hypochondriac state of non-medical students was not significant,and the difference was no statistically significant（P>0.05）. Conclusions The levels of negative emotions and hypochondriac state of medical college students were relatively low. Single GIM is available to improve negative emotions,and it also have a significant intervention effect on hypochondriac state. Using GIM intervention may be useful in enhancing psychological health for college students,while more stringent intervention strategies are needed to replicate this result.

Key words: Guided imagery and music, Music therapy, Hypochondriasis, Negative emotions, College students