Abstract: Objective To systematically review the incidence of occupational acute altitude sickness in grid corporations,sort out existing prevention and treatment measures,find out the current deficiencies of Chinese power grid enterprises in the prevention and control of acute altitude sickness referring to the relevant prevention and control measures of other countries,and provide the basis for improving the prevention and treatment of occupational acute altitude sickness in the future. Methods A systematic search were conducted on Pubmed,Embase,Cochrane Library,SinoMed,Wanfang and VIP databases from the date of entry to March 14,2021,supplemented by search results from Google and YouTube websites,to collect the studies on the incidence and prevention measures of occupational acute altitude sickness in power grid enterprises. Meta-analysis was performed using the meta package of R software. Results A total of 4 articles were included,3 of which reported the incidence,with a total of 36 839 people and 4 365 cases of acute altitude sickness. After excluding suspicious data,the meta-analysis found that the incidence of occupational acute altitude sickness in grid corporations was 13.46%（95%CI=7.69%-20.53%）. The hazards of occupational acute altitude sickness affected multiple systems throughout the body. The prevention measures mainly included plateau acclimatization and drugs usage. The treatment measures varied according to the severity of the disease. Conclusions At present,studies on the incidence of occupational acute altitude sickness in grid corporations are relatively scarce,and there are certain deficiencies in prevention and treatment measures. It is necessary to establish a systematic and complete technical solution for occupational acute altitude sickness in power grid enterprises as soon as possible,and strengthen personal protection and education of employees.

Key words: Acute altitude sickness, Grid corporations, Systematic reviews, Meta-analysis