Analysis on surveillance of adverse events following immunization in Hedong District of Tianjin City from 2018 to 2022

Abstract

Abstract: Objective To analyze the occurrence characteristics,classified diagnosis and vaccination safety of suspected adverse events following immunization（AEFI） in Hedong District of Tianjin City from 2018 to 2022. Methods The data of AEFI cases in Hedong District of Tianjin City from 2018 to 2022 were collected by AEFI monitoring module of China Information System for Disease Control and Prevention,and vaccination data of various vaccines in Hedong District of Tianjin City from 2018 to 2022 were collected by Tianjin Immunization Planning Information Management System. The classification,occurrence time,gender,age,vaccine types,and clinical diagnosis distribution of AEFI were analyzed,and the data were analyzed. Results A total of 488 AEFI cases were detected in Hedong District of Tianjin City from 2018 to 2022,including 424 cases of general reaction,40 cases of abnormal reaction and 24 cases of coupling syndrome. The 5-year reported incidence rates were 66.91/100 000 dose,80.97/100 000 dose,35.26/100 000 dose,14.49/100 000 dose,and 4.00/100 000 dose,respectively. The most reported cases of AEFI were among children aged 1-<5 years old,followed by children aged 0-<1 year old. AEFI cases were mainly concentrated in 0-<2 days after vaccination,accounting for 82.17% of all cases. Involving 32 vaccines,among which the top three reported incidence vaccines were measles vaccine,leprosy vaccine,and DTaP-Hib quadruple vaccine. The general reactions diagnosed clinically as fever,redness,swelling,and induration accounted for 64.96%,with a reported incidence of 27.40/100 000 doses. The abnormal reactions diagnosed clinically as allergic reactions（allergic rash,urticaria,etc.） accounted for 6.35%,with a reported incidence of 2.68/100 000 doses. Conclusion The incidence of AEFI reports in Hedong District of Tianjin City has a downward trend from 2018 to 2022,and the incidence of abnormal reaction reports has been decreasing year by year. However,it is still necessary to strengthen AEFI training and improve the monitoring sensitivity of AEFI.

Key words: Adverse event following immunization, Surveillance, Vaccines

CLC Number:

R186

GAO Yue, LI Yuanheng, LI Yingshu. Analysis on surveillance of adverse events following immunization in Hedong District of Tianjin City from 2018 to 2022. [J]OCCUPATION AND HEALTH, 2024, 40(12): 1684-1687.

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