OCCUPATION AND HEALTH ›› 2024, Vol. 40 ›› Issue (4): 547-553.

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Research progress on healthy effects of herbicide atrazine exposure on human and other mammal

BAI Yanan1,2, ZHOU Rong1, XING Weiwei3, YU Yue1, DAI Chuanchao2, BU Yuanqing1,4   

  1. 1. Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment, Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Ecology and Environment, Nanjing Jiangsu, 210042, China;
    2. Colloge of Life Sciences, Nanjing Normal University, Nanjing Jiangsu, 210023, China;
    3. Dalian Eco-environmental Affairs Service Center, Dalian Liaoning, 116000, China;
    4. Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing Jiangsu, 210044, China
  • Received:2023-05-19 Revised:2023-07-24 Online:2024-02-15 Published:2026-03-12
  • Contact: BU Yuanqing,Researcher,E-mail:byq@nies.org

Abstract: Objective Atrazine(ATZ) is a triazine herbicide widely used in the world.Residues of ATZ have been detected in water bodies in regions with a history of ATZ use.If it is used in excess for a long time,ATZ and its main degradation substances in the environment will be transferred through the food chain,which has potential toxic effects on the reproductive development,endocrine,nervous,immune and genetic systems of humans and other mammals,and then induce cancer.Therefore,this paper mainly reviews the research progress of ATZ exposure on human and other mammalian reproductive development,endocrine,nervous,immune,genetic system and potential carcinogenicity,and prospects the environmental health risks of ATZ use,and puts forward environmental management suggestions of ATZ,which is of great significance to further strengthen the use of ATZ.

Key words: Atrazine, Environmental health, Reproductive and developmental toxicity, Endocrine disruption, Neurotoxicity, Genotoxicity, Immunotoxicity, Carcinogenicity

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