Abstract: Objective To understand the core self-evaluation,organizational support and career adaptability of nosocomial infection prevention and control practitioners（IPCPs）,and analyze the mediating effect of core self-evaluation between organizational support and career adaptability. Methods In December 2022,a convenience sampling method was used to survey 322 IPCPs from 53 hospitals in Anhui Province using a general information questionnaire,core self-evaluation scale,organizational support scale,and occupational adaptation strength scale,and the data was analyzed. Results The total scores of core self-evaluation,organizational support and career adaptability of 322 IPCPs were （35.68±4.91）,（42.41±8.90） and （89.72±11.26）points,respectively. There was a positive correlation between the core self-evaluation,organizational support,and career adaptability of IPCPs（all P<0.01）. Core self-evaluation of IPCPs had a partial mediating effect between perceived organizational support and career adaptability（β=0.133,P<0.01）,accounting for 36.3% of the total effect value. Conclusions Core self-evaluation and career adaptability of 322 IPCPs from 5 hospitals in Anhui Province were at an above medium level,and perceived organizational support was at a medium level. Perceived organizational support of IPCPs can indirectly affect their career adaptability through core self-evaluation. Hospital managers should take positive measures to improve perceived organizational support and core self-evaluation of IPCPs,so as to enhance their career adaptability.

Key words: Nosocomial infection prevention and control practitioners, Career adaptability, Core self-evaluation, Perceived organizational support, Mediation analysis