Abstract: Objective To understand the immune levels of children aged ≤7 years old in Tacheng area of Xinjiang Uygur Autonomous Region,including measles,rubella,pertussis,diphtheria,tetanus and chickenpox,evaluate the effectiveness of immunization in the Tacheng area,and to provide reference for effective prevention and control of disease transmission and prevalence. Methods Enzyme linked immunosorbent assay（ELISA） was used to detect the levels of IgG antibodies against measles,rubella,pertussis,diphtheria,tetanus and chickenpox,and the data were analyzed. Results The antibody positivity rates for six diseases in children aged ≤7 years old in Tacheng area were 98.14% for measles,97.87% for rubella,28.85% for chickenpox,92.61% for diphtheria,82.21% for tetanus,and 72.41% for pertussis,respectively. The antibody positivity rates among children showed statistically significant differences in factors such as different region,age group,and vaccination history（all P<0.05）,while there was no statistically significant difference in gender（P>0.05）. Age group,region and vaccination history were all influencing factors for antibody positivity against tetanus,pertussis,and chickenpox（all P<0.05）. Conclusion Children ≤7 years old in Tacheng area of Xinjiang Uygur Autonomous Region have high immunity levels against measles,rubella and diphtheria,while their immunity levels against chickenpox,pertussis and tetanus are relatively low. Special attention should be paid to the outbreak and epidemic of pertussis and chickenpox,and efforts should be made to strengthen immunization and prevention among key populations and places,in order to improve the level of immunization and prevention among the population.

Key words: Measles, Rubella, Pertussis, Diphtheria, Tetanus, Chickenpox, Antibody levels