Monitoring and analysis of adverse events following immunization in Shiyan City from 2020 to 2022

Abstract

Abstract: Objective To analyze the characteristics of adverse events following immunization（AEFI） in Shiyan City and evaluate the safety of immunization. Methods Descriptive epidemiological methods were used to statistically analyze the AEFI monitoring report data and related vaccination data in Shiyan from 2020 to 2022. Results From 2020 to 2022,a total of 748 cases of AEFI were reported in Shiyan City,with an average annual reporting rate of 18.08/100 000 doses. Among reports,there were 710 common vaccine reactions（94.92%,17.17/100 000 doses） and 35 rare vaccine reactions（4.68%,0.85/100 000 doses）. The male to female ratio was 1.23∶1,and the most reports were in the 0-<3 years old group（591 cases,79.01%）. From June to September,there was an increase of report（361 cases,48.27%）. The reported incidence rates in various counties（cities,districts） ranged from 10.36/100 000 doses to 29.46/100 000 doses（χ²=71.198,P<0.01）. The rotavirus vaccine AEFI reporting rate was the highest（164.47/100 000 doses）. The abnormal reactions were mainly manifested as allergic rashes（0.65/100 000 doses）.The timely reporting rate and timely investigation rate of AEFI were 96.79% and 92.86%,respectively,and the coverage rate of reporting counties in each year was 100%. Conclusion The sensitivity of AEFI monitoring in Shiyan from 2020 to 2022 shows a downward trend,and individual areas need to strengthen monitoring. All vaccines are safe,and vaccination safety is standardized.

Key words: Adverse events following immunization, Safety, Monitoring

CLC Number:

R186

FU Lei, WANG Yaocheng, MEI Yong, LI Yanli. Monitoring and analysis of adverse events following immunization in Shiyan City from 2020 to 2022. [J]OCCUPATION AND HEALTH, 2025, 41(18): 2540-2545.

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