Abstract: Objective To analyze the epidemiological characteristics of adverse events following immunization(AEFI) in Fucheng District of Mianyang City from 2014 to 2023,and provide scientific basis for the safety evaluation of vaccination in Fucheng District of Mianyang City. Methods The monitoring case and vaccination data reported in Fucheng District of Mianyang City from 2014 to 2023 were collected and organized through the National AEFI Monitoring System,Sichuan Provincial Immunization Planning Information Management System,and China Immunization Planning Information Management System. A database was established using Excel 2010,and SPSS 22.0 statistical software was used for statistical processing. The count data was expressed in rate,and the rate comparison was conducted using χ² test,α=0.05. Results From 2014 to 2023,a total of 1 760 AEFI cases were reported in Fucheng District of Mianyang City,with no deaths reported. The reported incidence rate was 26.73/100 000,increasing from 25.60/100 000 in 2014 to 44.67/100 000 in 2023,with an average annual growth rate of 6.38%. The reported incidence rate showed an upward trend(χ²_trend=67.859,P<0.01). The incidence rate of general reactions was 24.52/100 000,and the incidence rate of abnormal reactions was 1.44/100 000. The reported incidence rate of AEFI in rural townships was higher than that in urban streets(χ²=55.917,P<0.01). The reporting time showed seasonal clustering characteristics with peaks(r=0.215,P<0.01),and more cases were reported from May to August. The male-to-female ratio of reported AEFI cases was 0.98∶1. The age group with the highest incidence of AEFI was 0-<2 years old,accounting for 51.82% of the cases. Conclusion The AEFI reports in Fucheng District of Mianyang City from 2014 to 2023 mainly focuses on general reactions,while the incidence of severe abnormal reactions was relatively low,reflecting good vaccine safety. However,it is still necessary to strengthen public health education,enhance the work ability of vaccination personnel,strengthen monitoring and improve monitoring sensitivity.

Key words: Vaccination, Abnormal reactions, Monitoring results