Abstract: Objective To establish a QuEChERS coupled with high performance liquid chromatography-tandem mass spectrometry（HPLC-MS/MS） method for determination of 8 aryloxyphenoxypropionate herbicides in bean products. Methods The samples were extracted with acetonitrile,purified with N-primary secondary amine（PSA） and anhydrous MgSO₄,separated with a Poroshell 120 EC-C₁₈ column,and detected with an alternate positive/negative ion electro spray ionization（ESI） mode under multiple reaction monitoring. External standard calibration curves were used for quantitative analysis. Results A good linear relationship between quizalofop-ethyl and propaquizafo in the range of 0.50-200.00 ng/mL,and the other six aryloxyphenoxypropionate herbicides in the range of 0.20-200.00 ng/mL,with a correlation coefficient of ≥0.999,limits of detectionof 0.01-1.26 μg/kg,and limits of quantification of 0.03-4.20 μg/kg. The average recoveries were 70.52%-100.03% with relative standard deviations（RSD） of 0.76%-9.28% at the spiked levels of 5,10,50 μg/kg. Conclusion The established method is simple,quick and sensitive,and accurate in both qualitative and quantitative analysis. It is suitable for the detection of 8 types of aryloxyphenoxypropionate herbicides in bean products.

Key words: Aryloxyphenoxypropionate herbicides, Bean products, QuEChERS, High performance liquid chromatography-tandem mass spectrometry, Determination