Abstract:

Objective To understand the vaccination status of rotavirus vaccine among children born in a district of Beijing from 2016 to 2024，so as to evaluate the effectiveness of rotavirus vaccine in preventing rotavirus diarrhea. Methods A descriptive analysis was performed on the basic information and rotavirus vaccine immunization history of children born from January 1，2016 to December 31，2024，and a retrospective cohort study was conducted to evaluate the protection rate of rotavirus vaccine. Results From 2016 to 2024，the total vaccination rates of the first to third doses of rotavirus vaccine were 34.40%，19.73% and 14.17%，respectively. The coverage rates of Lanzhou lamb rotavirus vaccine（LLR） were 18.42%，4.90% and 0.49%，respectively. The coverage rates of the first to third doses of imported oral pentavalent human-bovine reassort ant rotavirus vaccine（RV5） were 22.65%，21.02% and 19.38%，respectively. The coverage rates of LLR and RV5 among urban and Beijing residents were higher than those among rural and other provincial children. The coverage rates of RV5 in AA and AAA clinics were higher than those in A clinic. The full coverage rate of RV5 was higher than that of LLR. The overall protection rate of rotavirus vaccine was 44.10%，and the protection rate of three-dose vaccine was 54.76%，which was higher than that of one-dose vaccine 34.47% and two-dose vaccine 42.37%. Conclusion The coverage rate and the full vaccination rate of rotavirus vaccine are low among children in a district of Beijing，and rotavirus vaccine has a protective effect against rotavirus diarrhea. It is necessary to carry out targeted health education and personalized vaccination strategies for different groups，and actively promote the vaccination of rotavirus to reduce the incidence of rotavirus diarrhea in children.

Key words: Rotavirus vaccine, Vaccination, Vaccination rate, Full coverage rate, Vaccine effectiveness, Rotavirus diarrhea