OCCUPATION AND HEALTH ›› 2023, Vol. 39 ›› Issue (5): 626-629.

• Treatise • Previous Articles    

Determination of isopropyl diglycidyl ether in workplace air by solvent desorption-gas chromatography

LIU Meng-meng, ZHANG Jian, ZHANG Wan-chao, LYU Bo-yi, HAN Cheng, ZENG Qiang   

  1. Institute for Occupational Health,Tianjin Center for Disease Control and Prevention,Tianjin 300011,China
  • Received:2022-07-17 Revised:2022-08-08 Published:2026-03-03
  • Contact: ZHANG Jian,Deputy chief technician,E-mail:juanling_7402@126.com

Abstract: Objective To establish a method for determination of isopropyl diglycidyl ether(IGE) in workplace air by solvent desorption-gas chromatography. Methods The samples were collected with carbon tube and desorbed by 5% acetone-carbon disulfide,separated with the DB-FFAP gas chromatographic column,and detected by flame ionization detector(FID). Results The quantitative determination range of IGE was 3.0-919.0 μg/mL,with a correlation coefficient of 0.999 9. The limit of detection was 0.9 μg/mL. The lower limit of quantification was 3.0 μg/mL. Under 1.5 L sampling volume and 1.0mL extraction solution volume,the minimum detectable concentration was 0.6 mg/m3 and the minimum quantification concentration was 2.0 mg/m3. The relative standard deviation(RSD) of intra-assay and inter-assay precision was 1.6%-3.1% and 3.5%-4.9% respectively. The average extraction efficiency was 98.6%. The penetration capacity was >15.0 mg. The average collection efficiency was 100%. When placed in air,the samples could be stored for seven days. When placed in 4℃ refrigerator,the samples could be stored for 14 days. The potential coexistence of n-butanol and epichlorohydrin with IGE in the air did not interfere with the results of determination. Conclusion This method has high sensitivity,precision and accuracy and it is applicable for the on-site monitoring of IGE in workplace air.

Key words: Air of workplace, Isopropyl diglycidyl ether, Gas chromatography, Occupational health

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