Prevalence of depression in patients with chronic obstructive pulmonary disease in China：A meta analysis

Abstract

Abstract: Objective To systematically evaluate the prevalence of depression in patients with chronic obstructive pulmonary disease（COPD） in China. Methods CNKI,CBM,WanFang,VIP,PubMed,Embase and other databases were searched by computer. Studies on depression in COPD patients in China were included,and meta-analysis was performed using Stata 15.0 software. Results A total of 12 278 samples were included. The prevalence of depression in COPD patients in China was 25%（95%CI：24%-26%）. There were statistically significant differences in the prevalence among different groups in age,population origin,disease course,measurement tools,disease status and region（all P<0.01）. The prevalence of depression in people aged ≤65 years old（34.0%,95%CI：32.6%-35.4%） was higher than that in people aged >65 years old（22.3%,95%CI：21.5%-23.1%）,the prevalence of hospitalized patients（29.5%,95%CI：28.3%-30.6%） was higher than that of community patients（22.4%,95%CI：21.5%-23.3%）,and the prevalence of patients with disease course ≤10 years（32.6%,95%CI：30.9%-34.4%） was higher than that of patients with disease course >10 years（26.5%,95%CI：24.1%-28.9%）（all P<0.01）. The prevalence based on epidemiological research center depression scale,elderly depression scale,hospital depression scale,Zung' depression scale,and Hamilton depression scale was 17.0%（95%CI：14.5%-19.6%）,22.9%（95%CI：22.0%-23.8%）,25.0%（95%CI：23.1%-26.8%）,26.9%（95%CI：24.9%-29.0%） and 66.0%（95%CI：62.8%-69.3%）,respectively（all P<0.01）. The prevalence of patients in acute exacerbation period（26.1%,95%CI：24.4%-27.9%） was higher than that of patients in stable period（24.9%,95%CI：24.2%-25.7%）. The prevalence of eastern,central and western regions was 22.7%（95%CI：22.0%-23.5%）,54.3%（95%CI：49.5%-59.1%） and 65.4%（95%CI：61.8%-68.9%）,respectively（all P<0.01）. Conclusion There is a high prevalence of depression in COPD patients in China,and it is necessary to pay attention to the evaluation and intervention of patients' depression in clinical nursing work to promote their physical and mental health.

Key words: Prevalence, Chronic obstructive pulmonary disease, Depression

CLC Number:

R181.3

HAO Hai-qin, ZHANG Qing-qing, SHEN Li-li, ZHU Ya-li, JIA Jin-fang, HU Yi. Prevalence of depression in patients with chronic obstructive pulmonary disease in China：A meta analysis. [J]OCCUPATION AND HEALTH, 2023, 39(5): 687-691.

References

[1] WANG C,XU J,YANG L,et al.Prevalence and risk factors of chronic obstructive pulmonary disease in China(the China Pulmonary Health[CPH] study):A national cross-sectional study[J].Lancet,2018,391(10131):1706-1717.
[2] HALPIN D M G,CRINER G J,PAPI A,et al.Global initiative for the diagnosis,management,and prevention of chronic obstructive lung disease.The 2020 GOLD science committee report on COVID-19 and chronic obstructive pulmonary disease[J].Am J Respir Crit Care Med,2021,203(1):24-36.
[3] KHAYYATZADEH S S,SHAFIEE M,FAR P E,et al.Adherence to a healthy dietary pattern is associated with less severe depressive symptoms among adolescent girls[J].Psychiatry Res,2019(272):467-473.
[4] RENNARD S I.Chronic obstructive pulmonary disease:Linking outcomes and pathobiology of disease modification[J].Proc Am Thorac Soc,2006,3(3):276-280.
[5] HASIN D S,SARVET A L,MEYERS J L,et al.Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States[J].JAMA Psychiatry,2018,75(4):336-346.
[6] WILLGOSS T G,YOHANNES A M.Anxiety disorders in patients with COPD:A systematic review[J].Respir Care,2013,58(5):858-866.
[7] YOHANNES A M,KAPLAN A,HANANIA N A.Anxiety and depression in chronic obstructive pulmonary disease:Recognition and management[J].Cleve Clin J Med,2018,67(2):S11.
[8] MARSH S,GUCK T P.Anxiety and depression:Easing the burden in COPD patients[J].J Fam Pract,2016,65(4):246-256.
[9] ATLANTIS E,FAHEY P,COCHRANE B,et al.Bidirectional associations between clinically relevant depression or anxiety and COPD:A systematic review and meta-analysis[J].Chest,2013,144(3):766-777.
[10] FAN V S,GIARDINO N D,BLOUGH D K,et al.Costs of pulmonary rehabilitation and predictors of adherence in the National Emphysema Treatment Trial[J].COPD,2008,5(2):105-116.
[11] ZAREIFOPOULOS N,BELLOU A,SPIROPOULOU A,et al.Prevalence,contribution to disease burden and management of comorbid depression and anxiety in chronic obstructive pulmonary disease:A narrative review[J].COPD,2019,16(5-6):406-417.
[12] 艾飞玲,胡葵茹,石钰霖,等.基于纽卡斯尔-渥太华量表对中国吸烟队列研究文献的质量评价[J].中华疾病控制杂志,2021,25(6):722-729.
[13] 曾宪涛,刘慧,陈曦,等.Meta分析系列之四:观察性研究的质量评价工具[J].中国循证心血管医学杂志,2012,4(4):297-299.
[14] 曾雪峰,王晓霞,包勇,等.成都市社区慢性阻塞性肺疾病流行病学调查[J].中国呼吸与危重监护杂志,2011,10(1):30-32.
[15] 陈佳玲,张锋英,杭晶卿.慢性阻塞性肺疾病合并抑郁状况及影响因素分析[J].医学信息,2016,29(10):329.
[16] 陈静波,钟晓春,赖彩琴.不同通气障碍类型慢性阻塞性肺疾病患者伴发抑郁情绪的临床研究[J].热带医学杂志,2013,13(7):870-872.
[17] 黄娟,李光熙,金在艳,等.慢性阻塞性肺疾病急性加重对患者生活质量的影响[J].现代生物医学进展,2015,15(15):2863-2867.
[18] 江莲,陈建波,王兰,等.120 例慢性阻塞性肺疾病患者抑郁状态调查分析[J].浙江临床医学,2013,15(10):1486-1487.
[19] 李文雯,李晓聪,罗益锋,等.不同通气障碍和不同级别慢性阻塞性肺疾病患者抑郁情绪分析[J].中国老年学杂志,2014,34(16):4505-4507.
[20] 林南生,周尧生,何深文,等.慢性阻塞性肺疾病患者抑郁和焦虑发生的危险因素分析[J].岭南急诊医学杂志,2015(4):290-293.
[21] 罗红辉,陈炎城,李佳,等.对慢性阻塞性肺疾病稳定期患者焦虑抑郁的临床流行病学调查研究[J].黑龙江医学,2018,42(3):260-261.
[22] 汪斌超,周伯荣,田贤媚,等.稳定期COPD 患者认知和心理状况及其相关因素分析[J].安徽医科大学学报,2004,39(3):212-214.
[23] 王锐英,许建英,刘虎.慢性阻塞性肺疾病稳定期患者情绪障碍的相关因素分析[J].中国药物与临床,2016,16(4):463-466.
[24] 温晓雯,袁麟标,叶泽辉.东莞市中重度慢性阻塞性肺疾病患者合并抑郁症流行病学调查[J].中国医学创新,2014,11(18):90-92.
[25] 吴尚洁,唐丽,陈燕,等.慢性阻塞性肺疾病患者抑郁,焦虑情绪调查[J].中国临床心理学杂志,2006,14(4):405-406.
[26] 张海琴,李燕芹,刘斌,等.慢性阻塞性肺疾病稳定期患者的生活质量和精神状态调查[J].中国慢性病预防与控制,2010,18(1):15-17.
[27] 张馨,霍建民.焦虑,抑郁对慢性阻塞性肺疾病评分的影响[J].中华肺部疾病杂志,2014,7(4):25-28.
[28] 张莹,王静.328 例北京市房山区 COPD 患者焦虑抑郁相关因素[J].国际呼吸杂志,2017,37(23):1795-1798.
[29] 晁耀烁,许志强,李保顺.慢性阻塞性肺疾病患者抑郁症患病率及影响因素调查[J].中国临床康复,2005,9(4):209.
[30] AN L,LIN Y X,YANG T,et al.Predictive validity of BODE index for anxious and depressive symptoms in patients with chronic obstructive pulmonary disease[J].Chin Med J,2010,123(14):1845-1851.
[31] DENG D,ZHOU A,CHEN P,et al.CODEXS:a new multidimensional index to better predict frequent COPD exacerbators with inclusion of depression score[J].Int J Chron Obstruct Pulmon Dis,2020,15(1):249-259.
[32] DENG X,SONG J.Correlation analysis between depression and family fitness in chronic obstructive pulmonary disease inpatients:A cross-sectional study[J].Medicine (Baltimore),2018,97(52):e13946.
[33] LOERBROKS A,JIANG C Q,THOMAS G N,et al.COPD and depressive symptoms:Findings from the Guangzhou Biobank Cohort Study[J].Ann Behav Med,2012,44(3):408-415.
[34] LONG J,OUYANG Y,DUAN H,et al.Multiple factor analysis of depression and/or anxiety in patients with acute exacerbation chronic obstructive pulmonary disease[J].Int J Chron Obstruct Pulmon Dis,2020,15(1):1449-1464.
[35] TSE H N,TSENG C Z S,WONG K Y,et al.Frequent exacerbator:The phenotype at risk of depressive symptoms in geriatric COPD patients[J].Lung,2016,194(4):665-673.
[36] TSUI M S N,LUN F C T,CHENG L S L,et al.Risk factors for hospital readmission for COPD after implementation of the GOLD guidelines[J].Int J Tuberc Lung Dis,2016,20(3):396-401.
[37] WANG P,JIAO T,ZHU M L.The prevalence of anxiety and depression in patients with an acute exacerbation of COPD[J].Am J Respir Crit Care Med,2013:A2515-A2515.
[38] XIAO T,QIU H,CHEN Y,et al.Prevalence of anxiety and depression symptoms and their associated factors in mild COPD patients from community settings,Shanghai,China:A cross-sectional study[J].BMC Psychiatry,2018,18(1):1-7.
[39] XU W,COLLET J P,SHAPIRO S,et al.Independent effect of depression and anxiety on chronic obstructive pulmonary disease exacerbations and hospitalizations[J].Am J Respir Crit Care Med,2008,178(9):913-920.
[40] SIREY J A,RAUE P J,Alexopoulos G S.An intervention to improve depression care in older adults with COPD[J].Int J Geriatr Psychiatry,2007,22(2):154-159.
[41] BRAJER-LUFTMANN B,MARDAS M,STELMACH-MARDAS M,et al.Association between Anxiety,Depressive Symptoms,and Quality of Life in Patients Undergoing Diagnostic Flexible Video Bronchoscopy[J].Int J Environ Res Public Health,2021,18(19):10374.
[42] HANANIA N A,MÜLLEROVA H,LOCANTORE N W,et al.Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort[J].Am J Respir Crit Care Med,2011,183(5):604-611.
[43] JÁCOME C,FIGUEIREDO D,GABRIEL R,et al.Predicting anxiety and depression among family carers of people with chronic obstructive pulmonary disease[J].Int Psychogeriatr,2014,26(7):1191-1199.
[44] TSAI T Y,LIVNEH H,LU M C,et al.Increased risk and related factors of depression among patients with COPD:A population-based cohort study[J].BMC Public Health,2013,13(1):1-7.
[45] CHIESI F,PRIMI C,PIGLIAUTILE M,et al.Is the 15-item Geriatric Depression Scale a fair screening tool? A differential item functioning analysis across gender and age[J].Psychol Rep,2018,121(6):1167-1182.
[46] KATO T.Measurement invariance in the Center for Epidemiologic Studies-Depression(CES-D) scale among English-speaking Whites and Asians[J].Int J Environ Res Public Health,2021,18(10):5298.
[47] MITCHELL A J,VAZE A,RAO S.Clinical diagnosis of depression in primary care:a meta-analysis[J].Lancet,2009,374(9690):609-619.
[48] LARSEN C H,BENDSTRUP E,NEERGAARD M A.Screening tools for depression and anxiety in patients with chronic obstructive pulmonary Disease-A systematic review[J].COPD,2021:1-7.
[49] SOLER J,GUILLAUMOT A,SCHWITZER T,et al.Specific effect of exercise training on depression in COPD patients[J].Rev Mal Respir,2021,38(6):598-606.
[50] ATLANTIS E,FAHEY P,COCHRANE B,et al.Bidirectional associations between clinically relevant depression or anxiety and COPD:A systematic review and meta-analysis[J].Chest,2013,144(3):766-777.
[51] LIU L J,GUO Q.Life satisfaction in a sample of empty-nest elderly:A survey in the rural area of a mountainous county in China[J].Qual Life Res,2008,17(6):823-830.
[52] ZHONG N,WANG C,YAO W,et al.Prevalence of chronic obstructive pulmonary disease in China:A large,population-based survey[J].Am J Respir Crit Care Med,2007,176(8):753-760.