医务人员HIV职业暴露后预防性服药依从性调查问卷的构建

职业与健康 ›› 2024, Vol. 40 ›› Issue (1): 56-60.

医务人员HIV职业暴露后预防性服药依从性调查问卷的构建

李琦¹, 李辉², 李云霞³, 范璐^4a, 张丽辉^4a, 袁素娥^4ab

1.空军军医大学第一附属医院心理科,陕西西安 710032;
2.南华大学护理学院社区护理学教研室,湖南衡阳 421001;
3.中南大学湘雅护理学院,湖南长沙 410013;
4.中南大学湘雅医院 a临床护理学教研室, b国家老年疾病临床医学研究中心,湖南长沙 410008

收稿日期:2023-05-12 修回日期:2023-06-21 出版日期:2024-01-01 发布日期:2026-03-11
通信作者: 袁素娥,主任护师,E-mail：ldyse2018@csu.edu.cn
作者简介:李琦,女,护师,主要从事临床护理工作。
基金资助:
国家老年疾病临床医学研究中心老年疾病临床研究基金（2022LNJJ15）

Construction of the questionnaire on adherence to occupational HIV post-exposure prophylactic regimens among healthcare personnel

LI Qi¹, LI Hui², LI Yunxia³, FAN Lu^4a, ZHANG Lihui^4a, YUAN Sue^4ab

1. Department of Psychology, Air Force Military Medical University First Affiliated Hospital, Xi’an Shaanxi, 710032, China;;
2. Teaching and Research Section of Community Nursing, School of Nursing, University of South China, Hengyang Hunan, 421001, China;
3. Xiangya School of Nursing, Central South University, Changsha Hunan, 410013, China;
4. a Teaching and Research Section of Clinical Nursing, b National Clinical Medical Research Center for Geriatric Diseases, Xiangya Hospital of Central South University, Changsha Hunan, 410008, China

Received:2023-05-12 Revised:2023-06-21 Online:2024-01-01 Published:2026-03-11
Contact: YUAN Sue,Chief nurse,E-mail：ldyse2018@csu.edu.cn

摘要/Abstract

摘要： 目的构建《医务人员HIV职业暴露预防性用药的服药依从性问卷》,为下一步进行医务人员HIV职业暴露后预防提供参考依据。方法通过查阅文献、小组讨论初步拟定问卷条目池,于2020年8—10月实施2轮专家函询进行问卷条目的筛选与修改。结果 2轮专家函询的问卷有效回收率均为100%,专家权威系数分别为0.860和0.820,专家协调程度肯德尔系数分别为0.257和0.387。最终形成《医务人员HIV职业暴露后预防性服药依从性问卷》,包括暴露者一般信息、暴露后预防用药、用药依从性影响因素3部分,共50个条目。结论《医务人员HIV职业暴露后预防性服药依从性问卷》条目设置合理,易于理解,可作为评价我国HIV职业暴露后预防性用药依从性评价的工具。

关键词: 德尔菲法, 问卷编制, 职业暴露, 暴露后预防, 人类免疫缺陷病毒

Abstract: Objective To construct the questionnaire on adherence to occupational human immunodeficiency virus（HIV） post-exposure prophylactic regimens among healthcare personal,providing reference basis for the prevention of HIV occupational exposure among healthcare workers in the next step. Methods The questionnaire item pool was preliminarily formulated based on literature review and group discussion. Two rounds of expert inquiry were conducted from August to October 2020 to screen and modify questionnaire entries. Results The effective recovery rate of the two rounds of consultation was 100%. The authority coefficients were 0.860 and 0.820,and the coordination coefficients were 0.257 and 0.387. The questionnaire on adherence to occupational HIV post-exposure prophylactic regimens among healthcare personal was formulated after two rounds of consultation. There were 50 items in total,including the general information of exposed persons,the information of post-exposure prophylactic medication,and the influencing factors of medication adherence. Conclusion The questionnaire is reasonable,comprehensible,and can be used as a tool to evaluate the adherence to occupational HIV post-exposure prophylactic regimens.

Key words: Delphi method, Questionnaire development, Occupational exposure, Post-exposure prophylactic, Human immunodeficiency virus

中图分类号:

R181.2

李琦, 李辉, 李云霞, 范璐, 张丽辉, 袁素娥. 医务人员HIV职业暴露后预防性服药依从性调查问卷的构建. [J]职业与健康, 2024, 40(1): 56-60.

LI Qi, LI Hui, LI Yunxia, FAN Lu, ZHANG Lihui, YUAN Sue. Construction of the questionnaire on adherence to occupational HIV post-exposure prophylactic regimens among healthcare personnel. [J]OCCUPATION AND HEALTH, 2024, 40(1): 56-60.

参考文献

[1] 中华人民共和国国家卫生健康委员会.卫生部关于印发《医务人员艾滋病病毒职业暴露防护工作指导原则(试行)》的通知[EB/OL].(2004-04-06)[2020-09-21].http://www.nhc.gov.cn/wjw/gfxwj/201304/588fcab93194457cb2cdf3f150b3faac.shtml.
[2] 中国疾病预防控制中心性病艾滋病预防控制中心.《艾滋病病毒暴露后预防技术指南(试用)》[EB/OL].(2020-11-16)[2020-11-18].http://ncaids.chinacdc.cn/tzgggd/202011/t20201116_222780.html.
[3] 中国疾病预防控制中心.中华医学会感染病学分会艾滋病丙型肝炎学组.中国艾滋病诊疗指南(2018版)[J].新发传染病电子杂志,2019, 4(2):65-84.
[4] WHO.Global HIV,Hepatitis and STIs Programme[EB/OL].(2020-11)[2020-11-16].https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/data-use/hiv-data-and-statistics
[5] JOYCE M P,KUHAR D,BROOKS J T.Notes from the field:occupationally acquired HIV infection among health care workers-United States,1985-2013[J].MMWR Morb Mortal Wkly Rep,2015,63(53):1245-1246.
[6] 疾病预防控制局.解读《职业暴露感染艾滋病病毒处理程序规定》[EB/OL].(2015-07-23)[2020-09-21].http://www.nhc.gov.cn/jkj/s3586/201507/22321c7206ea4696aadb1695fd46d28c.shtml.
[7] MAATEN G,NYIRENDA M,BEADSWORTH M,et al.Post exposure prophylaxis of HIV transmission after occupational injuries in queen elizabeth central hospital,blantyre,malawi,2003-2008[J].Malawi Med J,2010,22(1):15-19.
[8] 傅亮. 艾滋病临床护理实践指南的构建研究[D].上海:复旦大学,2014.
[9] 李韩平,李宏,杨坤,等.河南部分艾滋病病人ART的临床效果以及基因型耐药性分析[J].中华微生物学和免疫学杂志,2005,25(3):194-198.
[10] CHEN J,ZHANG M,SHANG M,et al.Research on the treatment effects and drug resistances of long-term second-line antiretroviral therapy among HIV-infected patients from henan province in China[J].BMC Infect Dis,2018,18(1):571.
[11] TETTEH R A,NARTEY E T,LARTEY M,et al.Adverse events and adherence to HIV post-exposure prophylaxis:A cohort study at the Korle-Bu Teaching Hospital in Accra,Ghana[J].BMC Public Health,2015,15:573.
[12] 郭秀花. 医学现场调查技术与统计分析[M].北京:人民卫生出版社,2009:93-100.
[13] 徐海侠,李春兰.艾滋病病人抗病毒治疗服药依从性与生存质量的相关性[J].中国艾滋病性病,2018,24(3):238-240.
[14] 赵文宇. 艾滋病抗病毒治疗服药依从性及影响因素的研究[D].北京:中国疾病预防控制中心,2016.
[15] 肖敏,黄金,王红红,等.HIV阳性男男性行为者抗病毒治疗依从性现状及影响因素研究[J].中国艾滋病性病,2019,25(1):48-51.
[16] 曾琼,万彬,付莉,等.HIV阳性孕妇服药依从性的影响因素分析[J].护理研究,2018,32(2):259-261.
[17] 邵英,刘晓宁,何克静,等.感染HIV孕产妇的社会支持现状及其与服药依从性的相关性[J].中国艾滋病性病,2020,26(11):1190-1192.
[18] 张啟文,张金奖,谢学军,等.监狱服刑HIV感染者/AIDS患者抗病毒治疗服药依从性的影响因素[J].职业与健康,2019,35(19):2674-2677.
[19] 高岩,崔元斌,龚一谦,等.HIV感染者/AIDS病人抗病毒治疗服药依从性管理相关循证指南的质量评价[J].护理研究,2020,34(3):414-419.
[20] FORD N,MAYER K H.World health organization guidelines on post-exposure prophylaxis for hiv:Recommendations for a public health approach[J].Clin Infect Dis,2015,60(Suppl 3):S161-S164.
[21] New York State Department of Health AIDS Institute.Clinical guidelines program[EB/OL].(2020-06)[2021-01-20].https://www.hivguidelines.org/pep-for-hiv-prevention/pep/.
[22] Department of Health.HIV post-exposure prophylaxis:Guidance from the UK Chief Medical Officers’ Expert Advisory Group on AIDS[EB/OL].(2008-09-19)[2021-01-24].https://www.gov.uk/government/publications/eaga-guidance-on-hiv-post-exposure-prop-hylaxis.
[23] 周宇,刘梦雅,高莉莉,等.基于信息化的服药依从性促进工具研究进展[J].护理研究,2020,34(23):4186-4190.
[24] 胡美华,赵秀莉,赵艳春,等.医务人员感染性职业暴露后预防现状及改进探讨[J].中国护理管理,2020,20(2):250-253.
[25] AMINDE L N,TAKAH N F,DZUDIE A,et al.Occupational post-exposure prophylaxis(PEP) against human immunodeficiency virus(HIV) infection in a health district in Cameroon:assessment of the knowledge and practices of nurses[J].PLoS One,2015,10(4):124416.
[26] 田含章,易宜芳,李映兰.医护人员职业暴露后预防依从性及其影响因素研究进展[J].护理学杂志,2014,29(6):92-94.
[27] MITZEL L D,VANABLE P A.Necessity and concerns beliefs and HIV medication adherence:A systematic review[J].J Behav Med,2020, 43(1):1-15.
[28] KATZ I T,RYU A E,ONUEGBU A G,et al.Impact of HIV-related stigma on treatment adherence:Systematic review and meta-synthesis[J].J Int AIDS Soc,2013,16(3 Suppl 2):18640.
[29] 吴锋耀,董文逸,韦彩云,等.艾滋病高发地区传染病医院医护人员职业卫生防护体系建设[J].中国护理管理,2018,18(2):150-153.
[30] 解晨,孙珍,张静,等.综合医院医务人员职业接触防护体系建设与实践[J].中国护理管理,2015,15(9):1079-1082.