职业与健康 ›› 2024, Vol. 40 ›› Issue (12): 1721-1728.

• 综述 • 上一篇    

基于核酸适配体的牛奶中污染物检测技术的研究进展

张文娇, 李鸣, 史莹   

  1. 四川大学华西公共卫生学院/华西第四医院,四川 成都 610041
  • 收稿日期:2023-08-13 修回日期:2023-11-18 出版日期:2024-06-15 发布日期:2026-03-13
  • 通信作者: 史莹,讲师,E-mail:jennysing2013@163.com
  • 作者简介:张文娇,女,在读硕士研究生,研究方向为营养与食品卫生。
  • 基金资助:
    成都市科技局重点研发支撑计划技术创新研发项目(2021-YF05-00406-SN); 四川省科技厅应用基础项目(2021YJ0285)

Research progress of pollutant detection technology in milk based on nucleic acid aptamer

ZHANG Wenjiao, LI Ming, SHI Ying   

  1. West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu Sichuan, 610041, China
  • Received:2023-08-13 Revised:2023-11-18 Online:2024-06-15 Published:2026-03-13
  • Contact: SHI Ying,Lecturer,E-mail:jennysing2013@163.com

摘要: 近年来食品安全问题层出迭见,民众对牛奶及其制品的安全问题关注度日益提高。为了保障食品安全,保护人体健康,需要方便快捷的食品检测技术,定量检测出食品中的污染物。本文综述了色谱法、光谱法、电化学法等传统检测方法在食品污染物残留检测中的应用。在此基础上着重综述了基于核酸适配体技术的新检测技术在牛奶中多重污染物检测中的应用,包括对抗生素、重金属、黄曲霉毒素以及三聚氰胺残留等的检测,为之后开发多样便捷的核酸适配体技术提供参考。

关键词: 核酸适配体, 牛奶, 污染物, 检测

Abstract: The food safety issues have emerged one after anotherin recent years and the public is increasingly concerned about the safety of milk and its products.In order to ensure food safety and protect human health,convenient and rapid food testing techniques are needed to quantitatively detect contaminants in food. This paper reviews the application of traditional detection methods such as chromatography,spectroscopy,and electrochemical methods in the detection of food contaminant residues. On this basis,the paper focuses on the new detection method based on nucleic acid aptamer technology for multiple contaminants in milk,including antibiotics,heavy metals,aflatoxins,and melamine residues,to provide a reference for the development of diverse and convenient nucleic acid aptamer technology in the future.

Key words: Nucleic acid aptamer, Milk, Pollutant, Detection

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