中国男男性行为者暴露前预防使用意愿影响因素的meta分析

职业与健康 ›› 2024, Vol. 40 ›› Issue (20): 2864-2871.

中国男男性行为者暴露前预防使用意愿影响因素的meta分析

郑瑜¹, 王鑫^1,2, 邓媛^1,2, 王佳^1,3

1.电子科技大学医学院,四川成都 611731;
2.电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院护理部,四川成都610073;;
3.电子科技大学附属医院·四川省医学科学院·四川省人民医院儿科,四川成都 610072;

收稿日期:2024-02-15 修回日期:2024-03-05 出版日期:2024-10-15 发布日期:2026-03-17
通信作者: 王鑫,主任护师,E-mail：xinwang8403@163.com
作者简介:郑瑜,女,在读硕士研究生,研究方向为护理管理。
基金资助:
四川省护理科研课题（H22035）; 成都市医学科研课题（2023112）

Meta-analysis on the influencing factors of the willingness in using the pre-exposure prophylaxis among men who have sex with men in China

ZHENG Yu¹, WANG Xin^1,2, DENG Yuan^1,2, WANG Jia^1,3

1. School of Medicine,University of Electronic Science and Technology of China,Chengdu,Sichuan 611731,China;
2. Nursing Department,Chengdu Women's and Children's Central Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu,Sichuan 610073,China;
3. Sichuan Provincial People's Hospital,School of Medicine,University of Electronic Science and Technology of China,Chengdu,Sichuan 610072,China

Received:2024-02-15 Revised:2024-03-05 Online:2024-10-15 Published:2026-03-17
Contact: WANG Xin,Chief nurse,E-mail：xinwang8403@163.com

摘要/Abstract

摘要： 目的应用meta分析方法,探讨中国男男性行为者（men who have sex with men,MSM）暴露前预防（pre-exposure prophylaxis,PrEP）使用意愿的影响因素。方法系统检索中国知网、万方、中国生物医学文献数据库、维普、The Cochrane Library、Web of Science、PubMed和Embase建库至2023年6月6日发表的有关中国MSM PrEP使用意愿影响因素的文献。采用美国卫生保健质量和研究机构（agency for healthcare research and quality,AHRQ）推荐的横断面评价标准对文献进行质量评估,采用Stata 15.0软件进行meta分析。结果共纳入26篇文献,涉及样本量22 711例,对3篇及以上影响因素相同的文献进行meta分析。结果显示,再婚或与女性同居（OR=2.145,95%CI：3.270~1.521）、户籍为外省户口（OR=1.706,95%CI：1.393~2.089）、职业为学生（OR=1.407,95%CI：1.061~1.864）、知晓PrEP（OR=2.790,95%CI：1.973~3.944）、个人人类免疫缺陷病毒（human immunodeficiency virus,HIV）风险感知水平较高（OR=3.245,95%CI：1.535~6.869）、近1年接受过HIV检测（OR=1.909,95%CI：1.542~2.365）、有固定性伴侣（OR=1.825,95%CI：1.405~2.370）、近6个月坚持使用安全套（OR=0.409,95%CI：0.199~0.839）是我国MSM PrEP使用意愿的影响因素。结论再婚或与女性同居、户籍为非调查城市户口、职业为学生、知晓PrEP、个人HIV风险感知水平较高、有固定性伴侣、近1年接受过HIV检测的MSM暴露前预防用药的可能性更大,而近6个月坚持使用安全套的MSM暴露前预防用药的可能性较小。应针对目标人群实施相应的干预策略以提高PrEP的实际使用。

关键词: 男男性行为者, 暴露前预防, 使用意愿, 影响因素, 中国, Meta分析

Abstract: Objective To explore the influencing factors of the willingness to use pre-exposure prophylaxis（PrEP） for men who have sex with men（MSM） in China by means of meta-analysis. Methods A systematic search was conducted on the literature related to the factors influencing the willingness to use PrEP among Chinese MSM,published in databases such as China National Knowledge Infrastructure（CNKI）,Wanfang,China Biomedical Literature Database,VIP,the Cochrane Library,Web of Science,PubMed,and Embaseup to June 6,2023. The cross-sectional evaluation criteria recommended by the agency for healthcare research and quality（AHRQ） in the United States were used to evaluate the quality of the literature,and the Stata 15.0 software was used for meta-analysis. Results A total of 26 articles were included,involving a sample size of 22 711 cases. Meta analysis was conducted on 3 or more articles with the same influencing factors. The results showed that remarriage or cohabitation with women（OR=2.145,95%CI：3.270-1.521）,registered residence registration in other provinces（OR=1.706,95%CI：1.393-2.089）,occupation as a student（OR=1.407,95%CI：1.061-1.864）,awareness of PrEP（OR=2.790,95%CI：1.973-3.944）,high level of personal risk perception of human immunodeficiency virus（HIV）（OR=3.245,95%CI：1.535-6.869）,aving received diagnosis of HIV/AIDS in the past year（OR=1.909,95%CI：1.54-2.365）,having a fixed sexual partner（OR=1.825,95%CI：1.405-2.370）,and persisting in using condoms in the past six months（OR=0.409,95%CI：0.199-0.839） were the influencing factors of the willingness to use PrEP among Chinese MSM. Conclusion The MSM who remarried or cohabited with a female,had a registered residence in a non survey city,had a student occupation,knew PrEP,had a high level of personal HIV risk perception,had a fixed sexual partner,and had been tested for HIV in the past one year were more likely to take preventive drugs before exposure,while the MSM who insisted on using condoms in the past six months were less likely to take preventive drugs before exposure. Corresponding intervention strategies should be implemented for the target population to improve the practical use of PrEP.

Key words: Men who have sex with men, Pre-exposure prophylaxis, Willingness to use, Influencing factors, China, Meta-analysis

中图分类号:

R181.2

郑瑜, 王鑫, 邓媛, 王佳. 中国男男性行为者暴露前预防使用意愿影响因素的meta分析. [J]职业与健康, 2024, 40(20): 2864-2871.

ZHENG Yu, WANG Xin, DENG Yuan, WANG Jia. Meta-analysis on the influencing factors of the willingness in using the pre-exposure prophylaxis among men who have sex with men in China. [J]OCCUPATION AND HEALTH, 2024, 40(20): 2864-2871.

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