2017年滇中滇西居民砷硒内暴露水平分析

职业与健康 ›› 2023, Vol. 39 ›› Issue (14): 1925-1928.

2017年滇中滇西居民砷硒内暴露水平分析

栗旸¹, 杨建斌¹, 李建云¹, 狄娟¹, 张旭辉¹, 张瑞仙²

1.云南省疾病预防控制中心环境卫生所,云南昆明 650022;
2.云南省第一人民医院/昆明理工大学附属医院疾病预防控制科,云南昆明 650034

收稿日期:2022-09-29 修回日期:2022-11-07 出版日期:2023-07-15 发布日期:2026-03-24
通信作者: 张瑞仙,副主任医师,E-mail：41250668@qq.com
作者简介:栗旸,女,主任技师,主要从事理化检验与质控工作。
基金资助:
国家自然科学基金（82060305）

Analysis on internal exposure to arsenic and selenium in residents of central and western Yunnan in 2017

LI Yang¹, YANG Jianbin¹, LI Jianyun¹, DI Juan¹, ZHANG Xuhui¹, ZHANG Ruixian²

1. Institute of Environmental Health,Yunan Center for Disease Control and Prevention,Kunming Yunnan,650022,China;
2. Department of Disease Control and Prevention,First People's Hospital of Yunnan Province/Affiliated Hospital of Kunming University of Science and Technology,Kunming Yunnan,650034,China

Received:2022-09-29 Revised:2022-11-07 Online:2023-07-15 Published:2026-03-24
Contact: ZHANG Ruixian,Associate chief physician,E-mail：41250668@qq.com

摘要/Abstract

摘要： 目的掌握滇中、滇西常住居民砷、硒内暴露水平及其地区和人群分布特征。方法采用多阶段复杂抽样、成比例概率抽样以及分层随机抽样,在云南省选取监测点、调查单元和调查对象。按照知情同意原则,采集调查对象外周静脉血和尿样,并分装、转运、实验室检测。利用Excel、SPSS 25.0和GraphPad Prism 8进行数据整理与分析。结果 2017年共调查云南省滇中、滇西常住居民720人,有效血样、尿样分别为709、719人份。血砷、尿砷中位数分别为2.40、19.38 μg/L,血硒、尿硒分别为82.40、14.56 μg/L。不同地区间、城乡间常住居民血砷、尿砷、血硒、尿硒浓度比较,差异均有统计学意义（均P<0.05）;不同年龄段、不同性别常住居民血砷、尿砷浓度比较,差异均有统计学意义（均P<0.05）;男性尿硒浓度低于女性（P<0.01）。结论砷、硒内暴露水平在滇中、滇西常住居民中具有地区和人群分布差异,滇中常住居民血砷、血硒较滇西高。

关键词: 人体生物监测, 内暴露, 砷, 硒

Abstract: Objective To grasp the internal exposure to arsenic（As） and selenium（Se） in the permanent residents in central and western Yunnan,as well as regional and population distribution characteristics. Methods The multi-stage complex sampling,proportional probability sampling,and stratified random sampling were adopted to determine the monitoring points,survey units and respondents in Yunnan Province.In accordance with the principle of informed consent,the peripheral venous blood and urine samples of the subjects were collected,packed,transported,and tested of As and Se in the laboratory.Microsoft Excel,SPSS 25.0 and GraphPad Prism 8 were using for data sorting and analysis. Results A total of 720 permanent residents incentral and western Yunnan Province were surveyed in 2017,then the number of valid blood samples and urine samples were 709 and 719,respectively.The median of As in blood and urine was 2.40 and 19.38 μg/L respectively,while that of Se was 82.40 and 14.56 μg/L respectively.There were statistically significant differences in the concentrations of blood As,urine As,blood Se and urine Se among residents in different regions,and between urban and rural residents（all P<0.05）. There were statistically significant differences in the concentrations of blood As and urine Se among residents in different age and gender（all P<0.05）. The urine Se concentration of males was lower than that of females（P<0.01）. Conclusion The regional and population distribution differences of internal exposure to As and Se are found among the permanent residents in central and western Yunnan,and the blood As and Se of the residents in central Yunnan are higher than those in western Yunnan.

Key words: Human biomonitoring, Internal exposure, Arsenic, Selenium

中图分类号:

R181.3⁺4

栗旸, 杨建斌, 李建云, 狄娟, 张旭辉, 张瑞仙. 2017年滇中滇西居民砷硒内暴露水平分析. [J]职业与健康, 2023, 39(14): 1925-1928.

LI Yang, YANG Jianbin, LI Jianyun, DI Juan, ZHANG Xuhui, ZHANG Ruixian. Analysis on internal exposure to arsenic and selenium in residents of central and western Yunnan in 2017. [J]OCCUPATION AND HEALTH, 2023, 39(14): 1925-1928.

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