1990—2019年江苏省胆囊和胆道恶性肿瘤疾病负担及变化趋势分析

职业与健康 ›› 2023, Vol. 39 ›› Issue (16): 2230-2234.

1990—2019年江苏省胆囊和胆道恶性肿瘤疾病负担及变化趋势分析

梁季¹, 周金意², 刘付东¹, 韩仁强², 吴玲玲¹, 俞浩²

1.盐城市疾病预防控制中心慢性非传染性疾病预防控制科,江苏盐城 224001;
2.江苏省疾病预防控制中心慢性非传染性疾病防治所,江苏南京 210009

收稿日期:2022-11-09 修回日期:2023-01-03 发布日期:2026-03-24
通信作者: 俞浩,副主任医师,E-mail：49413268@qq.com
作者简介:梁季,女,副主任医师,主要从事慢性非传染性疾病预防控制工作。
基金资助:
江苏省卫生计生委医学科研课题（H2017018）

Analysis on disease burden and changing trend of malignant tumors of gallbladder and biliary tract in Jiangsu Province from 1990-2019

LIANG Ji¹, ZHOU Jinyi², LIU Fudong¹, HAN Renqiang², WU Lingling¹, YU Hao²

1. Department of Chronic Non-communicable Disease Prevention and Control,Yancheng Center for Disease Control and Prevention,Yancheng Jiangsu 224001,China;
2. Institute for Chronic Non-communicable Disease,Jiangsu Center for Disease Control and Prevention,Nanjing Jiangsu 210009,China

Received:2022-11-09 Revised:2023-01-03 Published:2026-03-24
Contact: YU Hao,Associate chief physician,E-mail：49413268@qq.com

摘要/Abstract

摘要： 目的分析1990—2019年江苏省胆囊和胆道恶性肿瘤（以下简称胆道肿瘤）疾病负担及变化趋势,以了解其现状和流行趋势,为制定防控措施提供参考依据。方法利用2019年全球疾病负担（global burden of disease,GBD）研究结果,选取发病率、死亡率、伤残调整寿命年（disability adjusted of life years,DALY）、早死损失寿命年（years of life lost,YLL）和伤残损失寿命年（years lost due to disability,YLD）等疾病负担指标,应用GBD 2019全球标准人口对相关指标进行标化,采用Joinpoint 模型计算年度变化百分比（annual percentage change,APC）分析胆道肿瘤疾病负担的变化趋势。结果 2019年江苏省胆道肿瘤发病共4 055例,死亡共3 105例。1990—2019年,发病率从1.34/10万上升至4.92/10万,死亡率从1.24/10万上升至3.76/10万,上升趋势均有统计学意义（APC=5.55%、4.81%,均P<0.05）,标化发病率、标化死亡率、标化DALY率、标化YLL率和标化YLD率均呈上升趋势（APC=2.63%、1.71%、1.71%、1.71%和2.74%,均P<0.05）。结论 1990—2019年江苏省胆道肿瘤发病率、死亡率呈上升趋势,疾病负担沉重,应加强胆道肿瘤的筛查和防治工作。

关键词: 胆囊和胆道恶性肿瘤, 疾病负担, 变化趋势

Abstract: Objective To analyze the disease burden and trends of malignant tumors of the gallbladder and biliary tract（here in after referred to as biliary tract tumors） in Jiangsu Province from 1990 to 2019,in order to understand the current situation and epidemic trend,and provide scientific basis for the formulation of prevention and control measures. Methods Using the results of the 2019 global burden of disease（GBD） study,disease burden indicators such as morbidity,mortality,disability adjusted of life years（DALY）,years of life lost（YLL） and years lost due to disability（YLD） were selected.The GBD 2019 global standard population was used to standardize the relevant indicators,and the Joinpoint model was used to calculate the annual percentage change（APC） to analyze the changing trend of the disease burden of biliary tract tumors. Results In 2019,there were 4 055 cases of biliary tract tumors in Jiangsu Province and 3 105 deaths.From 1990 to 2019,the incidence rate increased from 1.34/100 000 to 4.92/100 000,and the mortality rate increased from 1.24/100 000 to 3.76/100 000,both the upward trends were statistically significant（APC=5.55%,4.81%,both P<0.05）,the standardized incidence rate,standardized mortality rate,standardized DALY rate,standardized YLL rate and standardized YLD rate all showed an upward trend（APC=2.63%,1.71%,1.71%,1.71%,2.74%,all P<0.05）. Conclusion From 1990 to 2019,the incidence and mortality of biliary tract tumors in Jiangsu Province show a significant upward trend,and the disease burden is heavy,so the screening and prevention of biliary tract tumors should be strengthened.

Key words: Malignant tumors of gallbladder and biliary tract, Disease burden, Trend of change

中图分类号:

R181.3⁺9

梁季, 周金意, 刘付东, 韩仁强, 吴玲玲, 俞浩. 1990—2019年江苏省胆囊和胆道恶性肿瘤疾病负担及变化趋势分析. [J]职业与健康, 2023, 39(16): 2230-2234.

LIANG Ji, ZHOU Jinyi, LIU Fudong, HAN Renqiang, WU Lingling, YU Hao. Analysis on disease burden and changing trend of malignant tumors of gallbladder and biliary tract in Jiangsu Province from 1990-2019. [J]OCCUPATION AND HEALTH, 2023, 39(16): 2230-2234.

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