关键词: 风险评估模型, 化学毒物风险评估, 应用

Abstract: Objective To explore the differences and applicability of different risk assessment models in the risk assessment of key occupational hazard factors. Methods The Unite States Environmental Protection Agency's non-carcinogenic risk assessment model（EPA model） and Singapore's semi-quantitative risk assessment model for occupational exposure to hazardous chemicals（Singapore model） were used to assess the occupational health risk of eight major occupational hazards in workplace in Zhuhai City. The characteristics of various risk assessment models were judged according to the results and consistency test. Results A total of 2 074 samples of eight key occupational hazard factors were detected,of which 15 samples exceeded the standard. The qualitative results of the two models were basically consistent in six major occupational hazard factors,while they were different in xylene and trichloroethylen. The samples judged as unacceptable risk by the EPA model reached 165（7.96%） compared to 5（0.24%） by the Singapore model. The Fisher's exact probability method showed result of P<0.05 for testing the consistency of qualitative conclusions between the two models,and the result of Kappa analysis was K=0.54（P<0.05）. Conclusions The risk assessment results of eight major occupational hazard factors were different between EPA model and Singapore model. The Singapore model is more conservative,while the EPA model is more likely to draw an unacceptable conclusion. In practical application,the occupational health risk assessment model should be selected scientifically according to the characteristics of occupational exposure.

Key words: Risk assessment model, Chemical toxicant risk assessment, Application