深圳市2型糖尿病及合并症患者健康相关生命质量研究

职业与健康 ›› 2023, Vol. 39 ›› Issue (2): 221-226.

深圳市2型糖尿病及合并症患者健康相关生命质量研究

赵明烨^1a,b, 任溢男^1a,b, 唐平^2a, 曹伟灵^2b, 黄永平^2c, 宫芳芳^2d

1.中国药科大学 a 国际医药商学院，b 药物经济学评价研究中心，江苏南京 211198;
2.深圳市罗湖医院集团a全科医学科，b药学中心，c笋岗社康中心，d党政办公室，广东深圳 518001

收稿日期:2022-06-28 修回日期:2022-12-06 发布日期:2026-03-02
通信作者: 宫芳芳，中级经济师，E-mail：fang670872977 @163.com
作者简介:赵明烨，男，在读硕士研究生，研究方向为卫生政策与药物经济学。
基金资助:
国家自然科学基金青年项目（71603278）

Study on health-related quality of life of patients with type 2 diabetes and its complications in Shenzhen City

ZHAO Ming-ye^1a,b, REN Yi-nan^1a,b, TANG Ping^2a, CAO Wei-ling^2b, HUANG Yong-ping^2c, GONG Fang-fang^2d

1. a International Pharmaceutical Business School，b Pharmacoeconomic Evaluation Research Center，China Pharmaceutical University，Nanjing Jiangsu 211198，China;
2. a General Medicine Department，b Pharmacy Center，c Sungang Community Health Center，d Party and Government Office，Shenzhen Luohu Hospital Group，Shenzhen Guangdong 518001，China

Received:2022-06-28 Revised:2022-12-06 Published:2026-03-02
Contact: GONG Fang-fang，Intermediate economist，E-mail：fang 670872977@163.com

摘要/Abstract

摘要： 目的分析深圳市糖尿病人群健康相关生命质量及其影响因素。方法于2021年9—12月对深圳市罗湖区各大医院及社区卫生中心展开调研，最终确定634名18~92岁的2型糖尿病患者为研究对象。采用欧洲质量-5维度-5水平健康量表（European quality-5 dimension-5 levels questionnaire，EQ-5D-5L）、视觉检查评分（visual analogue scale，VAS）测算患者健康效用值。利用t检验及方差分析进行单因素检验，Tobit回归探究影响因素。结果本研究人群平均EQ-5D-5L效用值为0.888±0.205，VAS得分为（76.471±17.682）分。此外，研究测算了糖尿病合并其他疾病患者的效用值，高血压为0.873±0.014，高血脂为0.886±0.012，心力衰竭为0.792±0.083，心肌梗死为0.887±0.083，中风为0.569±0.070，冠心病心绞痛为0.765±0.067，慢性胃肠道疾病为0.840±0.036，生殖器疾病为0.847±0.043，视网膜病变为0.809±0.041，肾衰竭为0.699±0.110，外周血管疾病为0.821±0.055，皮肤溃疡为0.771±0.064，癌症为0.538±0.139。单因素分析结果表明，年龄、是否住院、空腹血糖值、学历、是否饮酒、是否吸烟、是否锻炼、有无合并症、有无脑卒中、有无冠心病心绞痛、有无肾衰竭、有无皮肤溃疡、有无癌症之间健康效用值的差异均有统计学意义（均P<0.05）。回归模型结果表明，年龄大、学历低、锻炼少、住院、合并症、中风、癌症是糖尿病患者健康效用值低的影响因素（均P<0.05）。结论深圳市2型糖尿病患者的健康相关生命质量低于正常人群，合并疾病对糖尿病患者生命质量影响大，应重视提高患者的自我管理与疾病防护意识。

关键词: 2型糖尿病, 糖尿病合并症, EQ-5D-5L, 生命质量

Abstract: Objective To analyze the health-related quality of life and its influencing factors of diabetic population in Shenzhen City. Methods A survey was conducted on major hospitals and community health centers in Luohu District of Shenzhen City from September to December 2021，and 634 type 2 diabetes patients aged 18-92 years old were finally selected as the search objects.The European quality-5 dimension-5 levels questionnaire（EQ-5D-5L） scale，and visual analogue score（VAS） were used to measure the patient's health utility.The univariate tests were performed using t-test and analysis of variance，and Tobit regression was used to explore influencing factors. Results The mean EQ-5D-5L utility of the study population was 0.888±0.205，and the VAS score was 76.471±17.682 points.In addition，the study calculated the utility of patients with diabetes and other diseases，specifically：hypertension was 0.873±0.014，hyperlipidemia was 0.886±0.012，heart failure was 0.792±0.083，myocardial infarction was 0.887±0.083，stroke was 0.569±0.070，coronary heart disease angina was 0.765±0.067，chronic gastrointestinal disease was 0.840±0.036，genital disease was 0.847±0.043，retinopathy was 0.809±0.041，renal failure was 0.699±0.110，peripheral vascular disease was 0.821±0.055，skin ulcers was 0.771±0.064，cancer was 0.538±0.139.The results of univariate analysis showed that there were statistically significant differences in health utility among different groups in age，whether hospitalization，fasting blood glucose，education，drinking，smoking，exercise，comorbidities，stroke，coronary heart disease angina，renal failure，skin ulcer and cancer（all P<0.05）. The regression model results showed that older age，lower education，less exercise，hospitalization，comorbidities，stroke，and cancer were the influencing factors of low health utility in diabetic patients（all P<0.05）. Conclusion The health-related quality of life of patients with type 2 diabetes in Shenzhen City is lower than that of the normal population，and the comorbid diseaseshave a great impact on the quality of life of patients with diabetes，so it is necessary to pay attention to improving patients' self-management and disease prevention awareness.

Key words: Type 2 diabetes, Diabetes comorbidities, EQ-5D-5L, Quality of life

中图分类号:

R181.3⁺7

赵明烨, 任溢男, 唐平, 曹伟灵, 黄永平, 宫芳芳. 深圳市2型糖尿病及合并症患者健康相关生命质量研究. [J]职业与健康, 2023, 39(2): 221-226.

ZHAO Ming-ye, REN Yi-nan, TANG Ping, CAO Wei-ling, HUANG Yong-ping, GONG Fang-fang. Study on health-related quality of life of patients with type 2 diabetes and its complications in Shenzhen City. [J]OCCUPATION AND HEALTH, 2023, 39(2): 221-226.

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