Abstract: Objective To analyze the correlation between psychological resilience and general well-being of nurses in grade-A,tertiary hospitals in Wuhan City,and to provide reference for strengthening humanistic care and general well-being of nurses. Methods In this study,the convenience sampling method was adopted,and the self-made general information questionnaire,the Connor-Davidson resilience scale（CD-RISC） and the general well-being schedule（GWBS） were used. From August to September,2022,a questionnaire survey was conducted among 1 099 nurses in 5 grade III,class A hospitals in Wuhan,and the data were analyzed. Results The average score of psychological resilience of nursing staff was（68.06±17.77）points for women and（69.45±22.10）points for men. The average score of general well-being was （68.80±10.31）points for women and （71.80±10.82）points for men. There were statistically significant differences in the general well-being of nursing staff at different ages,working years,professional titles and educational levels（all P<0.05）. In addition to the low negative correlation between the scores of GWBS and the scores of concerns about health of CD-RISC（P<0.01）,the scores of other factors were positively correlated with the scores of CD-RISC（all P<0.05）. The scores of self-reliance,optimism,tenacity in CD-RISC and educational level can positively predicte the total score of GWBS（all P<0.01）. Conclusions The general well-being of nursing staff in Wuhan needs to be improved. Age,working years,professional titles and education levels all affect the general well-being of nursing staff. Strong psychological resilience is a protective factor for the general well-being. It is necessary to strengthen humanistic care for nursing staff and enhance their internal work motivation.

Key words: Nursing staff, Psychological resilience, General well-being