Contamination trend and exposure risk assessment of aflatoxins in different commercially available foods

Abstract

Abstract: Objective To understand the contamination status of aflatoxins in different food in Hebei Province,quantitatively determine the aflatoxins in 9 commercially available foods,evaluate their exposure levels and potential health risks,and provide data support for relevant departments' early warning. Methods From 2021 to 2023,a total of 404 samples of food sold in Hebei Province were collected. The samples were extracted with acetonitrile-water（84+16）,purified with an immunoaffinity column,detected by liquid chromatography-tandem triple quadrupole mass spectrometry,quantified with isotope internal standard method. Based on the aflatoxin B1 content data and nutritional monitoring consumption data,the exposure level of aflatoxin B1 was assessed. Results The detection rate of aflatoxin B1 in food was the highest,at 12.13%. Among various types of food,peanut butter had the highest detection rate of aflatoxin B1,with an average detection value of 93.3 μg/kg. The exposure risk of peanut butter was relatively high,with the margin of exposure（MOE） of 72.99. Conclusion The contamination of aflatoxin B1 in food sold in different markets in Hebei Province should be highly concerned,especially the exposure risk of peanuts and peanut butter to residents.

Key words: Aflatoxin, Food contamination, Exposure risk assessment

CLC Number:

R155.3

SHANG Lei, LYU Junqing, QI Zhicai, WANG Liying, REN Beibei, WANG Yucan. Contamination trend and exposure risk assessment of aflatoxins in different commercially available foods. [J]OCCUPATION AND HEALTH, 2024, 40(24): 3342-3346.

References

[1] RUSHINGB R,SELIM M.Aflatoxin B1:A review on metabolism,toxicity,occurrence in food,occupational exposure,and detoxification methods[J].Food Chem Toxicol,2019,124:81-100.
[2] ISCHRENK D,BIGNAMI M,BODIN L,et al.Risk assessment of aflatoxins in food[J].EFSA J,2020,18(3):137-142.
[3] KEW M C.Aflatoxins as a cause of hepatocellular carcinoma[J].J Gastrointest Liver Dis,2013,22:305-310.
[4] 中华人民共和国国家卫生和计划生育委员会,国家食品药品监督管理总局.中华人民共和国国家标准:GB 2761—2017[S].北京:中国标准出版社,2017:1-7.
[5] COMMISSlON REGULATION(EC).Setting maximum levels for certain contaminants in foodstuffs:NO 1881/2006[S].Brussels:European Commission,2006:20-22
[6] 中华人民共和国国家卫生和计划生育委员会,国家食品药品监督管理总局.中华人民共和国国家标准:GB 5009.22—2016[S].北京:中国标准出版社,2017:1-7.
[7] 环境保护部.中国人群暴露参数手册(成人卷)[M].北京:中国环境出版社,2013:217-232.
[8] 刘书贵,尹怡,单奇,等.广东省鳜鱼和杂交鳢中孔雀石绿和硝基呋喃残留调查及暴露评估[J].中国食品卫生杂志,2015,27(5):553-558.
[9] 胡文敏,董海燕,宁忻,等.云南省部分食品黄曲霉毒素B1膳食暴露风险评估[J].食品安全质量检测学报,2020,11(15):5215-5219.
[10] 眭世闺,曾肖寒,李凤标,等.2018—2022年广西壮族自治区贵港市食用植物油中黄曲霉毒素B1监测结果分析及暴露风险评估[J].中国油脂,2023,48(10):87-92.
[11] EFSA.Opinion of the scientific committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic[J].EFSA J,2005,282:1-31.
[12] European Food Safety Authority.Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to the potential increase of consumer health risk by a possible increase of the existing maximum levels for aflatoxins in almonds,hazelnuts and pistachios and derived products[J].EFSA J,2007,446:1-127.
[13] World Health Organization.Second workshop on reliable evaluation of low-level contamination of food[R].Rome:WHO,1995,1-18.
[14] 陈炳卿. 现代食品卫生学[M].北京:人民卫生出版社,2001,58-89.
[15] 徐炜桢. 郫县豆瓣黄曲霉毒素B1污染状况及季节变化分析[J].中国调味品,2018(9):36-40.
[16] 段淑芬,胡文广,戴良香.花生黄曲霉毒素国家标准与绿色贸易壁垒[J].中国农学通报,2006,22(6):95-98.
[17] 董文亚,陈晨,赵秀兰,等.山东省市售花生及其制品中黄曲霉毒素B1污染状况与膳食暴露风险评估[J].中国油脂,2023,48(7):67-72.
[18] 王春双,范云燕,龙兮,等.南宁市粮油食品中黄曲霉毒素B1的暴露风险评估[J].现代预防医学,2020,47(2):252-255.
[19] 韩德娟,李凤玲,李晋,等.2021年泰安市粮油食品中黄曲霉毒素B1污染状况及膳食暴露风险评估[J].中国油脂,2023,48(7):73-78.
[20] 杨雅茂,尹礼国,陈露,等.西南地区辣椒干制品中黄曲霉毒素污染状况及风险评估[J].中国酿造,2023,42(2):126-131.
[21] 陈露,尹礼国,张超,等.干制辣椒中黄曲霉毒素B1污染及暴露风险研究进展[J].云南化工,2022,1(49):6-9.
[22] 袁鹏,张利锋,杨瑞春,等.河南省市售食品中黄曲霉毒素污染状况分析[J].中国卫生检验杂志,2020,30(1):100-103.
[23] 王君,刘秀梅,张志强.中国人群膳食黄曲霉毒素致肝癌的暴露评估[J].中华预防医学杂志,2009,43(6):478-481.