Abstract:

Objective To analyze the disease burden and premature mortality probability of breast cancer and common malignant cancers of the reproductive system among females in Chaoyang District of Beijing City，and to provide decision-making basis for formulating relevant prevention and control strategies. Methods The death registration data of female registered residents in Chaoyang District of Beijing City from 2003 to 2022 in the Beijing Death Registration and Reporting Information System were collected，and statistical indicators such as population mortality，standardized mortality，years of life lost（YLL），premature mortality probability and their average annual percent change（AAPC） for breast cancer and common malignant cancers of the reproductive system were analyzed. Excel 2016，SPSS 17.0 and Joinpoint 4.6.0.0 software were used for statistical analysis. Results From 2003 to 2022，the numbers of deaths from breast，cervical，uterine and ovarian cancers in women in Chaoyang District of Beijing City were 2 701，481，578 and 1 255 cases，respectively，and the crude mortality rate showed an upward trend（AAPC=2.490%，4.904%， 4.775%，5.544%，all P<0.01）. Age-specific mortality rates for breast，cervical，uterine and ovarian cancers showed an upward trend（AAPC=69.100%，43.286%，50.854%，44.424%，all P<0.01）. The probability of premature mortality for cervical，uterine and ovarian cancers showed an upward trend（AAPC=4.343%，3.062%，3.945%，all P<0.05）.The YLL rates of cervical，uterine and ovarian cancers showed an upward trend（AAPC= 4.093%，4.291%，4.408%，all P<0.05）. The crude mortality and YLL rates of breast cancer in the age group of ≥80 years showed an upward trend（AAPC=3.888%，3.538%，both P<0.01），the crude mortality and YLL rates of cervical cancer in the age group of 50-<60 years showed an upward trend（AAPC=8.643%， 8.545%，both P<0.05），the crude mortality rates of ovarian cancer in the age groups of 50-<60 and 60-<70 years showed an upward trend（AAPC=3.993%，5.450%，both P<0.05），and the YLL rate in the age groups of 60-<70 years showed an upward trend（AAPC=5.457%，P<0.05）. Conclusion From 2003 to 2022，the burden of breast cancer and common malignant cancers of the reproductive system in women in Chaoyang District of Beijing City are increasing，and the government should strengthen the prevention and control of breast cancer and common malignant cancers of the reproductive system. The mortality rate and YLL rate of ovarian cancer are higher than those of cervical and uterine cancers，so more attention should be paid to the prevention and control of ovarian cancer.

Key words: Breast cancer, Malignant cancers of the reproductive system, Mortality, Years of life lost, Average annual percent change