关键词: 细颗粒物, 脑卒中, 早死寿命损失年, 每千人寿命损失年, 疾病负担, 大气污染

Abstract: Objective To analyze the burden of stroke in Suzhou City from 2012 to 2021 attributed to exposure to fine particulate matter（PM_2.5） in the atmosphere. Methods The 2019 Global Burden of Disease（GBD2019） data was used to analyze the number of deaths,mortality rate,years of life loss（YLL）,and years of life loss per thousand people（YLL rate） attributed to PM_2.5 in early stroke life loss in Suzhou City. Results The number of deaths,mortality rate,YLL,and YLL rates caused by stroke among the population aged 25 and above in Suzhou City showed an increasing trend from 2012 to 2021（all P<0.01）. The cumulative number of stroke deaths attributed to PM_2.5 was 26 513,with a YLL of 402 215 person years and a YLL rate of 7.45‰,both of which were significantly higher in males than females. With the increase of years,the number of stroke deaths attributed to PM_2.5,as well as the YLL and YLL rates,showed a decreasing trend（all P<0.01）. If Suzhou City maintained at the national first level standard level（15 μG/m³）,it could reduce stroke deaths by 13 541 people and YLL by 201 689 people per year in the past decade. Conclusions It is that stroke life loss attributed to PM_2.5 seriously endangers the health of residents in Suzhou,and the disease burden varies among different genders and age groups. As atmospheric PM_2.5 continues to decrease,the burden of stroke attributed to PM_2.5 continues to decrease. Further improving air quality is of great significance for improving the health of residents.

Key words: Fine particulate matter, Stroke, YLL, YLL rate, Burden of disease, Air pollution