我国慢性阻塞性肺疾病患者抑郁患病率meta分析

摘要/Abstract

摘要： 目的系统评价中国慢性阻塞性肺疾病（chronic obstructive pulmonary disease,COPD）患者抑郁的患病率。方法计算机检索CNKI、万方、维普等数据库,纳入国内COPD患者抑郁的研究。Meta分析采用Stata 15.0进行。结果共纳入总样本量为12 278例。我国COPD患者的抑郁患病率为25%（95%CI：24%~26%）。不同年龄、人群来源、病程、测量工具、疾病状态和地区之间的患病率比较,差异均有统计学意义（均P<0.01）,年龄≤65岁人群抑郁症患病率（34.0%,95%CI：32.6%~35.4%）高于年龄>65岁人群（22.3%,95%CI：21.5%~23.1%）、住院患者患病率（29.5%,95%CI：28.3%~30.6%）高于社区（22.4%,95%CI：21.5%~23.3%）、病程≤10年患病率（32.6%,95%CI：30.9%~34.4%）高于病程>10年（26.5%,95%CI：24.1%~28.9%）（均P<0.01）。流行病学研究中心抑郁量表、老年抑郁量表、医院抑郁量表、Zung 氏抑郁量表、汉密尔顿抑郁量表的患病率分别为17.0%（95%CI：14.5%~19.6%）、22.9%（95%CI：22.0%~23.8%）、25.0%（95%CI：23.1%~26.8%）,26.9%（95%CI：24.9%~29.0%）、66.0%（95%CI：62.8%~69.3%）（均P<0.01）。急性加重期患病率（26.1%,95%CI：24.4%~27.9%）高于稳定期（24.9%,95%CI：24.2%~25.7%）,东部、中部、西部地区的患病率分别为22.7%（95%CI：22.0%~23.5%）、54.3%（95%CI：49.5%~59.1%）、65.4%（95%CI：61.8%~68.9%）（均P<0.01）。结论我国COPD患者抑郁患病率较高,临床护理工作中应加强对患者抑郁状态的评估和干预,促进患者身心健康。

关键词: 患病率, 慢性阻塞性肺疾病, 抑郁

Abstract: Objective To systematically evaluate the prevalence of depression in patients with chronic obstructive pulmonary disease（COPD） in China. Methods CNKI,CBM,WanFang,VIP,PubMed,Embase and other databases were searched by computer. Studies on depression in COPD patients in China were included,and meta-analysis was performed using Stata 15.0 software. Results A total of 12 278 samples were included. The prevalence of depression in COPD patients in China was 25%（95%CI：24%-26%）. There were statistically significant differences in the prevalence among different groups in age,population origin,disease course,measurement tools,disease status and region（all P<0.01）. The prevalence of depression in people aged ≤65 years old（34.0%,95%CI：32.6%-35.4%） was higher than that in people aged >65 years old（22.3%,95%CI：21.5%-23.1%）,the prevalence of hospitalized patients（29.5%,95%CI：28.3%-30.6%） was higher than that of community patients（22.4%,95%CI：21.5%-23.3%）,and the prevalence of patients with disease course ≤10 years（32.6%,95%CI：30.9%-34.4%） was higher than that of patients with disease course >10 years（26.5%,95%CI：24.1%-28.9%）（all P<0.01）. The prevalence based on epidemiological research center depression scale,elderly depression scale,hospital depression scale,Zung' depression scale,and Hamilton depression scale was 17.0%（95%CI：14.5%-19.6%）,22.9%（95%CI：22.0%-23.8%）,25.0%（95%CI：23.1%-26.8%）,26.9%（95%CI：24.9%-29.0%） and 66.0%（95%CI：62.8%-69.3%）,respectively（all P<0.01）. The prevalence of patients in acute exacerbation period（26.1%,95%CI：24.4%-27.9%） was higher than that of patients in stable period（24.9%,95%CI：24.2%-25.7%）. The prevalence of eastern,central and western regions was 22.7%（95%CI：22.0%-23.5%）,54.3%（95%CI：49.5%-59.1%） and 65.4%（95%CI：61.8%-68.9%）,respectively（all P<0.01）. Conclusion There is a high prevalence of depression in COPD patients in China,and it is necessary to pay attention to the evaluation and intervention of patients' depression in clinical nursing work to promote their physical and mental health.

Key words: Prevalence, Chronic obstructive pulmonary disease, Depression

中图分类号:

R181.3

郝海琴, 张清清, 沈丽丽, 朱亚历, 贾金芳, 胡艺. 我国慢性阻塞性肺疾病患者抑郁患病率meta分析. [J]职业与健康, 2023, 39(5): 687-691.

HAO Hai-qin, ZHANG Qing-qing, SHEN Li-li, ZHU Ya-li, JIA Jin-fang, HU Yi. Prevalence of depression in patients with chronic obstructive pulmonary disease in China：A meta analysis. [J]OCCUPATION AND HEALTH, 2023, 39(5): 687-691.

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