工作场所积尘中6种水溶性无机阴离子的离子色谱测定法

职业与健康 ›› 2025, Vol. 41 ›› Issue (13): 1744-1749.

工作场所积尘中6种水溶性无机阴离子的离子色谱测定法

马晓曼¹, 李韵冰¹, 林森¹, 李婉依², 王玉江¹, 谢俊卿¹

1.北京市丰台区疾病预防控制中心理化检验科,北京 100070;
2.北京农学院国际学院,北京 102206

收稿日期:2025-04-12 修回日期:2025-04-28 发布日期:2025-12-11
通信作者: 王玉江,主任技师,E-mail：yujiangwang@126.com;谢俊卿,主任医师,E-mail：78706311@qq.com
作者简介:马晓曼,女,主管技师,主要从事理化检验工作。
基金资助:
国家自然科学基金（82373626）

Determination of six water-soluble inorganic anions in workplace dust by ion chromatography

MA Xiaoman¹, LI Yunbing¹, LIN Sen¹, LI Wanyi², WANG Yujiang¹, XIE Junqing¹

1. Department of Physical and Chemical Testing, Beijing Fengtai Center for Diseases Control and Prevention, Beijing 100070, China;
2. College of International Education, Beijing University of Agriculture, Beijing 102206, China

Received:2025-04-12 Revised:2025-04-28 Published:2025-12-11
Contact: WANG Yujiang,Chief technician,E-mail：yujiangwang@126.com;XIE Junqing,Chief physician,E-mail：78706311@qq.com

摘要/Abstract

摘要： 目的为提高工作场所环境监测效率,探索同时测定积尘中氟化物、氯化物、氯酸盐、硝酸盐、硫酸盐和高氯酸盐6种水溶性无机阴离子的离子色谱检测方法。方法样品依次涡旋、超声、离心后,通过0.2 μm微孔滤膜和Ba/Ag/H柱过滤后上机,利用氢氧化钾梯度淋洗程序,在IonPac AS19色谱柱得到有效分离,经抑制器降低背景值后用电导检测器检测。结果 6种待测物在0.100~10.000 mg/L（0.100~10.000、0.010~0.500、0.500~50.000和0.005~0.150 mg/L）浓度范围内线性关系良好,相关系数（r）均>0.999;方法检出限为0.001~0.139 mg/L,定量限为0.003~0.463 mg/L;在低、中、高3个浓度添加水平的回收率在83.8%~118.3%之间,相对标准偏差（RSD）为0.064%~3.917%。结论本方法准确性好,线性范围宽,操作简便快速,可同时测定工作场所积尘中6种水溶性无机阴离子。

关键词: 离子色谱, 工作场所, 积尘, 水溶性无机阴离子, 同时测定

Abstract: Objective To improve the efficiency of workplace environmental monitoring,explore an ion chromatography detection methods for simultaneously measuring six water-soluble inorganic anions in dust accumulation,including fluoride,chloride,chlorate,nitrate,sulfate,and perchlorate. Methods The samples were sequentially vortexed,sonicated,and centrifuged,and then filtered through a 0.2 μm microporous membrane and a Ba/Ag/H column before being loaded onto a computer. Effective separation was achieved using a potassium hydroxide gradient elution program on an IonPac AS19 chromatographic column. The background value was reduced by a suppressor and detected using a conductivity detector. Results The linear relationship between the six test substances was good within the concentration range of 0.100-10.000 mg/L（0.100-10.000,0.010-0.500,0.500-50.000, 0.005-0.150 mg/L）,and the correlation coefficients（r） were all greater than 0.999. The limits of detection of the method were 0.001-0.139 mg/L,and the limits of quantitation were 0.003-0.463 mg/L. The recovery rates at low,medium,and high concentration levels ranged from 83.8% to 118.3%,with relative standard deviations（RSD） of 0.064% to 3.917%. Conclusion This method has good accuracy, wide linear range,simple and fast operation,and can simultaneously determine six water-soluble inorganic anions in workplace dust accumulation.

Key words: Ion chromatography, Workplace, Dust accumulation, Water soluble inorganic anions, Simultaneous determination

中图分类号:

R155.5

马晓曼, 李韵冰, 林森, 李婉依, 王玉江, 谢俊卿. 工作场所积尘中6种水溶性无机阴离子的离子色谱测定法. [J]职业与健康, 2025, 41(13): 1744-1749.

MA Xiaoman, LI Yunbing, LIN Sen, LI Wanyi, WANG Yujiang, XIE Junqing. Determination of six water-soluble inorganic anions in workplace dust by ion chromatography. [J]OCCUPATION AND HEALTH, 2025, 41(13): 1744-1749.

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