芜湖市某大型电器制造公司员工甲状腺结节检出率及影响因素分析

职业与健康 ›› 2025, Vol. 41 ›› Issue (6): 721-725.

• 论著 • 下一篇

芜湖市某大型电器制造公司员工甲状腺结节检出率及影响因素分析

李磊¹, 武艳¹, 王江波^2a, 赵晚君^2a, 张先翠^2b, 陈剑平^2a

1.皖南医学院研究生学院,安徽芜湖 241002;
2.皖南医学院第一附属医院 a甲乳外科,b健康管理中心,安徽芜湖 241001

收稿日期:2024-07-29 修回日期:2024-12-10 出版日期:2025-03-15 发布日期:2025-12-16
通信作者: 陈剑平,主任医师,E-mail：chenjianping003@163.com
作者简介:李磊,男,在读硕士研究生,研究方向为甲乳外科。
基金资助:
国家自然科学基金青年科学基金项目（823015751003724）

Analysis of thyroid nodule detection rate and influencing factors among employees in a large electrical appliance manufacturing company in Wuhu City

LI Lei¹, WU Yan¹, WANG Jiangbo^2a, ZHAO Wanjun^2a, ZHANG Xiancui^2b, CHEN Jianping^2a

1. Graduate School,Wannan Medical College,Wuhu,Anhui 241002,China;
2. a Department of Thyroid and Breast Surgery,b Health Management Center,The First Affiliated Hospital of Wannan Medical College,Wuhu,Anhui 241001,China

Received:2024-07-29 Revised:2024-12-10 Online:2025-03-15 Published:2025-12-16
Contact: CHEN Jianping,Chief physician,E-mail：chenjianping003@163.com

摘要/Abstract

摘要： 目的了解芜湖市某大型电器制造公司员工甲状腺结节现状,并分析其危险因素,为预防甲状腺结节提供一定依据。方法选取芜湖市某大型电器制造公司2022年1—7月于皖南医学院第一附属医院健康管理中心进行职业健康检查的4 159例职业健康检查者为研究对象,年龄18~85岁;通过彩色多普勒超声检查确定是否患有甲状腺结节,分为非甲状腺结节组（n=1 546）和甲状腺结节组（n=2 613）,对不同年龄段甲状腺结节检出情况及特点进行分析;探讨不同年龄段甲状腺结节影响因素时采用多因素logistic回归分析确定独立危险因素。结果 4 159名研究对象甲状腺结节,总检出率为62.83%,其中男性甲状腺结节700例,检出率为49.16%;女性甲状腺结节1 913例,检出率为69.95%,差异有统计学意义（P<0.01）;对不同年龄段甲状腺结节人群检出率比较,差异有统计学意义,且结节检出率随年龄增高而上升（χ²=171.102,P<0.01）。多因素logistic回归分析结果显示,性别、年龄、手术史、谷草/谷丙转氨酶、促甲状腺激素、游离四碘甲状腺原氨酸、促甲状腺激素异常是皖南片区电器制造业员工是否有甲状腺结节的独立危险因素。结论皖南片区电器制造业员工甲状腺结节发生与年龄密切相关,提示该地区电器制造业员工及管理者应关注对不同年龄段甲状腺结节的筛查。

关键词: 电器制造业, 甲状腺结节, 年龄, 危险因素

Abstract: Objective To understand the current status of thyroid nodules among employees in a large electrical manufacturing company in Wuhu City,and analyze its risk factors,so as to provide a certain basis for the prevention of thyroid nodules. Methods A total of 4 159 employees aged 18 to 85 from a large electrical manufacturing company in Wuhu City who underwent occupational health examinations at the health management center of the First Affiliated Hospital of Wannan Medical College from January to July 2022 were selected as the research subjects. Determine whether employees had thyroid nodules through color Doppler ultrasonography,and divide them into non-thyroid nodules group（n=1 546） and thyroid nodules group（n=2 613）. The detection and characteristics of thyroid nodules in different age groups were analyzed. Multivariate logistic regression analysis was used to determine independent risk factors for thyroid nodules in different age groups. Results The total detection rate of 4 159 subjects was 62.83%,including 700 cases of male thyroid nodules with a detection rate of 49.16%,and 1 913 cases of female thyroid nodules,with a detection rate of 69.95%. There was a statistically significant difference in the detection rate of thyroid nodules among employees of different genders（P<0.01）. There was a statistically significant difference in the detection rate of thyroid nodules among different age groups,and the detection rate of thyroid nodules increased with age（χ²=171.102,P<0.01）. Multivariate logistic regression analysis showed that gender,age,surgical history,aspartate/alanine aminotransferase,thyrotropin,free tetraiodothyronine,and thyrotropin abnormalities were independent risk factors for thyroid nodules in electrical appliance manufacturing employees in southern Anhui region. Conclusion The occurrence of thyroid nodules in electrical appliance manufacturing industry in southern Anhui region is closely related to age,suggesting that employees and managers in the electrical appliance manufacturing industry in this area should pay attention to the screening of thyroid nodules in different ages groups.

Key words: Electrical appliance manufacturing, Thyroid nodules, Age, Risk factor

中图分类号:

R181.3⁺7

李磊, 武艳, 王江波, 赵晚君, 张先翠, 陈剑平. 芜湖市某大型电器制造公司员工甲状腺结节检出率及影响因素分析. [J]职业与健康, 2025, 41(6): 721-725.

LI Lei, WU Yan, WANG Jiangbo, ZHAO Wanjun, ZHANG Xiancui, CHEN Jianping. Analysis of thyroid nodule detection rate and influencing factors among employees in a large electrical appliance manufacturing company in Wuhu City. [J]OCCUPATION AND HEALTH, 2025, 41(6): 721-725.

参考文献

[1] 中国内分泌代谢病专科联盟.甲状腺结节诊治行业标准[J].中华内分泌代谢杂志,2022,38(7):552-554.
[2] KUO J H,MCMANUS C,LEE J A.Analyzing the adoption of radiofrequency ablation of thyroid nodules using the diffusion of innovations theory:understanding where we are in the United States?[J].Ultrasonography,2022,41(1):25-33.
[3] LI Y,JIN C,LI J,et al.Prevalence of thyroid nodules in China:A health examination cohort-based study[J].Front Endocrinol,2021,12:676144.
[4] 李彦娟,王磊,王钰,等.甲状腺结节发病率调查及影响因素分析[J].中国综合临床,2020,36(5):455-459.
[5] SU Y,ZHANG Y,ZHAO M,et al.Association between thyroid nodules and volume and metabolic syndrome in an iodine-adequate area:A large community-based population study[J].Metab Syndr Relat Disord,2019,17(4):217-222.
[6] 齐力. 中国成为全球消费电子和家用电器重要制造基地[J].中国对外贸易,2024(2):72-73.
[7] GALAVIZ K I,WEBER M B,STRAUS A,et al.Global diabetes prevention interventions:A systematic review and network meta-analysis of the real-world impact on incidence,weight,and glucose[J].Diabetes Care,2018,41(7):1526-1534.
[8] 中国老年2型糖尿病防治临床指南编写组,中国老年医学学会老年内分泌代谢分会,中国老年保健医学研究会老年内分泌与代谢分会,等.中国老年2型糖尿病防治临床指南(2022年版)[J].中华内科杂志,2022,61:39.
[9] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2020年版)[J].中华糖尿病杂志,2021,13(4):315-409.
[10] 中华医学会,中华医学杂志社,中华医学会全科医学分会,等.高血压基层诊疗指南(2019年)[J].中华全科医师杂志,2019,18(4):301-313.
[11] 中国血脂管理指南修订联合专家委员会.中国血脂管理指南(2023年)[J].中国循环杂志,2023,38(3):237-271.
[12] 陈晓韵,徐明彤,林刁珠,等.40岁以上人群甲状腺结节与代谢指标之间的关联性[J].中山大学学报(医学版),2018,39(3):369-376.
[13] 刘雅思,张先翠,谢郁芳,等.不同BMI职业健康检查人群甲状腺结节检出情况和影响因素分析[J].齐齐哈尔医学院学报,2023,44(10):972-978.
[14] 赖晓英,欧阳平,朱宏,等.甲状腺结节检出情况及影响因素:10年309 576例职业健康检查人群分析[J].南方医科大学学报,2020,40(2):268-273.
[15] DUBLIN J C,PAPAZIAN M,ZAN E,et al.Predictive value of a genomic classifier in indeterminate thyroid nodules based on nodule size[J].JAMA Otolaryngol Head Neck Surg,2022,148(1):53-60.
[16] 留碧丽,夏文霞,李敏,等.超声检查及引导穿刺活检在甲状腺微小结节良恶性中的鉴别诊断价值[J].医学影像学杂志,2021,31(11):1864-1867.
[17] MOON J H,HYUN MK,LEE J Y,et al.Prevalence of thyroid nodules and their associated clinical parameters:A large-scale,multicenter-based health checkup study[J].Korean J Intern Med,2018,33(4):753-762.
[18] CHEN Y,ZHU C,CHEN Y,et al.The association of thyroid nodules with metabolic status:A cross-sectional SPECT-China study[J].Int J Endocrinol,2018,2018:6853617.
[19] LIANG Q,YU S,CHEN S,et al.Association of changes in metabolic syndrome status with the incidence of thyroid nodules:A prospective study in Chinese adults[J].Front Endocrinol(Lausanne),2020,11:582.
[20] XU L,ZENG F,WANG Y,et al.Prevalence and associated metabolic factors for thyroid nodules:A cross-sectional study in southwest of China with more than 120 thousand populations[J].BMC Endocr Disord,2021,21(1):175.
[21] OSPINA N S,PAPALEONTIOU M.Thyroid nodule evaluation and management in older adults:A review of practical considerations for clinical endocrinologists[J].Endocr Pract,2021,27(3):261-268.
[22] ZHANG C,GAO X,HAN Y,et al.Correlation between thyroid nodulesand metabolic syndrome:a systematic review and Meta-analysis[J].Front Endocrinol(Lausanne),2021,12:730279.
[23] 阮小风,张建军,夏红梅,等.非酒精性脂肪性肝病与甲状腺结节异病同治理论探析[J].中西医结合肝病杂志,2021,31(1):81-82,89.
[24] PIANTANIDA E,IPPOLITO S,GALLO D,et al.The interplay between thyroid and liver:Implications for clinical practice[J].Endocrinol Invest,2020,43(7):885-899.
[25] 姚宏,胡艳,饶开晴,等.雌激素-雌激素受体通路影响母鸡脂肪肝发生的可能机制[J].动物营养学报,2021,33(1):85-94.
[26] SADEGHI H,JAHANBAZI F,SADEGHI H,et al.Metformin attenuates oxidative stress and liver damage after bile duct ligation in rats[J].Res Pharm Sci,2019,14(2):122-129.

芜湖市某大型电器制造公司员工甲状腺结节检出率及影响因素分析

Analysis of thyroid nodule detection rate and influencing factors among employees in a large electrical appliance manufacturing company in Wuhu City

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