男男性行为HIV感染者生存质量及影响因素研究

职业与健康 ›› 2025, Vol. 41 ›› Issue (6): 800-804.

男男性行为HIV感染者生存质量及影响因素研究

张佳玉, 徐昊, 陈玮华, 王旭婷

上海市黄浦区疾病预防控制中心结核病与艾滋病防制科,上海 200001

收稿日期:2024-06-27 修回日期:2024-07-22 出版日期:2025-03-15 发布日期:2025-12-16
通信作者: 王旭婷,主管医师,E-mail：ayu451@foxmail.com
作者简介:张佳玉,女,主管医师,主要从事感染性疾病防控工作。
基金资助:
上海市黄浦区科委课题（HLQ202014）; 上海市黄浦区青年医师培养资助计划（2021QN25）; 中国疾病预防控制中心公共卫生领域卫生健康标准化前期研究项目（BZ2023-Q040）

Study on the quality of life and influencing factors among man who have sex with man living with HIV

ZHANG Jiayu, XU Hao, CHEN Weihua, WANG Xuting

Tuberculosis,AIDS and STD Prevention and Control Department,Shanghai Huangpu District Center for Disease Control and Prevention,Shanghai 200001,China

Received:2024-06-27 Revised:2024-07-22 Online:2025-03-15 Published:2025-12-16
Contact: WANG Xuting,Physician in charge,E-mail：ayu451@foxmail.com

摘要/Abstract

摘要： 目的了解上海市黄浦区人类免疫缺陷病毒（human immunodeficiency virus,HIV）抗体阳性男男性行为者（men who have sex with men,MSM）的生存质量及其影响因素。方法 2023年3—9月在上海市黄浦区招募HIV阳性MSM进行问卷调查,采用世界卫生组织艾滋病生命质量测量简表评估其生活质量,采用多重线性回归分析其生存质量的影响因素。结果纳入HIV阳性MSM 55例,生存质量总评分为（77.01±11.41）分,其中生理领域为（11.95±2.21）分,心理领域为（11.65±2.57）分,独立性领域为（13.47±1.64）分,社会关系领域为（12.78±2.63）分,环境领域为（13.32±2.61）分,精神世界领域为（13.84±3.33）分。单因素分析显示,不同居住地、教育程度、婚姻状态、治疗时间、健康自评和艾滋病相关耻辱的HIV阳性MSM的生存质量差异均有统计学意义（均P<0.05）。多重线性回归分析结果表明,健康自评较好是影响生活质量的正向因素,而感受耻辱为负向因素。结论上海市黄浦区HIV阳性MSM的生存质量受多方面因素影响,应开展针对性工作,不断消除艾滋病歧视,全方位提高患者生存质量。

关键词: 人类免疫缺陷病毒感染者, 男男性行为者, 生活质量, 艾滋病相关羞辱和歧视

Abstract: Objective To explore the quality of life（QOL） and influencing factors among man who have sex with man living with HIV（MSM-HIV） in Huangpu District of Shanghai. Methods From March to September 2023,MSM-HIV were recruited in Huangpu District of Shanghai for a questionnaire survey.The QOL was assessed by the World Health Organization Quality of Life Questionnaire for HIV brief version（WHOQOL-HIV-BREF）,and the influencing factors of their QOL were analyzed using multiple linear regression. Results Totally 55 MSM-HIV were included,with a total QOL score of（77.01±11.41）points,including physiological domain（11.95±2.21）points,psychological domain（11.65±2.57）points,independence domain（13.47±1.64）points,social relationship domain（12.78±2.63）points,environmental domain（13.32±2.61）points,and mental domain（13.84±3.33）points. Univariate analysis showed that there were statistically significant differences in the QOL of MSM-HIV in different places of residence,education level,marital status,treatment time,self-rated health,and HIV/AIDS related-stigma and discrimination（all P<0.05）. The results of multiple linear regression analysis indicated that self-rated good health was a positive factor affecting QOL,while feeling stigma and discrimination was a negative factor. Conclusion The QOL of MSM-HIV in Huangpu District of Shanghai is affected by many factors. Targeted work should be carried out to eliminate AIDS discrimination and improve the QOL of patients in an all-round way.

Key words: Human immunodeficiency virus infected person, Man who have sex with man, Quality of life, AIDS related stigma and discrimination

中图分类号:

R183.9

张佳玉, 徐昊, 陈玮华, 王旭婷. 男男性行为HIV感染者生存质量及影响因素研究. [J]职业与健康, 2025, 41(6): 800-804.

ZHANG Jiayu, XU Hao, CHEN Weihua, WANG Xuting. Study on the quality of life and influencing factors among man who have sex with man living with HIV. [J]OCCUPATION AND HEALTH, 2025, 41(6): 800-804.

参考文献

[1] 上海市卫生健康委员会.我市艾滋病持续控制在低流行水平[EB/OL].(2023-12-01)[2024-04-01].https://wsjkw.sh.gov.cn/xwfb/20231201/0d1ce0b9af8a4f798c637696dcff2b8f.html.
[2] 北京市卫生健康委员会.北京市艾滋病疫情呈现3个特点[EB/OL].(2023-11-27)[2024-04-01].https://wjw.beijig.gov.cn/xwzx_20031/xwfb/202311/t20231127_3309850.html.
[3] 江苏省政府艾滋病防治工作委员会办公室. 2023年全省艾滋病防治工作进展[EB/OL].(2023-11-30)[2024-04-01].http://wjw.jiangsu.gov.cn/art/2023/11/30/art_7312_11084979.html.
[4] 王茂美. 自我与他者之间:艾滋病患者的“双重”歧视问题——基于云南L艾滋病防治中心的实证调查[J].医学与哲(A),2016,37(7):37-39.
[5] BULGARELLI A T P R.AIDS and discrimination,the disease in the contextual labour environment[J].Ciência Cuidado e Saúde,2013,12(4):797-803.
[6] 李现红,何国平,王红红,等.HIV/AIDS相关羞辱和歧视量表的编制及评价[J].中华护理杂志,2010,45(6):496-499.
[7] 刘为民,何丽云,王建,等.世界卫生组织艾滋病生存质量量表中文版介绍及其使用说明[J].中国中医药信息杂志,2009,16(10):1-2.
[8] 方积乾,郝元涛,李彩霞.世界卫生组织生活质量量表中文版的信度与效度[J].中国心理卫生杂志,1999,13(4):203-205.
[9] ANDERSSON G Z,REINIUS M,ERIKSSON L E,et al.Stigma reduction interventions in people living with HIV to improve health-related quality of life[J].Lancet HIV,2020,7(2):e129-e140.
[10] LAZARUS J V,SAFREED-HARMON K,BARTON S E,et al.Beyond viral suppression of HIV-the new quality of life frontier[J].BMC Med,2016,14(1):94.
[11] The World Health Organization Quality of Life Assessment(WHOQOL).Position paper from the World Health Organization[J].Soc Sci Med,1995,41(10):1403-1409.
[12] 李现红,刘立珍,何国平,等.男男性行为HIV感染者艾滋病相关羞辱和歧视的调查分析[J].中华护理杂志,2013,48(2):142-146.
[13] 徐迪,端琼丽,潘玲,等.WHOQOL-BREF用于评价HIV感染者生活质量的信、效度研究[J].中华疾病控制杂志,2022,26(5):576-582.
[14] 杨建珍,何华仙,张杨,等.HIV/AIDS患者生活质量及相关因素的研究[J].实用预防医学,2007,14(6):1740-1741.
[15] 李晓春,高丽,王丽艳,等.云南省澜沧县艾滋病病毒感染者及患者生存质量现状及相关因素研究[J].中华疾病控制杂志,2011,15(7):571-574.
[16] 张王君,魏秀青,周珍红,等.湖南省HIV-1低病毒血症患者的生存质量及影响因素调查[J].中国感染控制杂志,2023,22(6):660-666.
[17] 闫丽,刘小翠,苏金星,等.北京市HIV/AIDS患者生存质量现状及影响因素分析[J].中国性科学,2022,31(2):157-160.
[18] 谢年华,江洪波,许骏,等.武汉市HIV/AIDS未治疗患者生存质量及影响因素研究[J].中华疾病控制杂志,2015,19(12):1204-1207.
[19] 杨翌,张孔来,王克荣,等.HIV感染者/AIDS患者生活质量及其影响因素研究[J].中国艾滋病性病,2005,11(4):244-246.
[20] 陈敏,张瑞丹,杨翌.HIV感染者/AIDS患者生存质量及其影响因素分析[J].中国艾滋病性病,2009,15(5):517-518.
[21] 张少晨,张勇,樊爱青,等.上海市男男性行为人群中HIV感染者生存质量及其影响因素分析[J].中国性科学,2021,30(2):135-138.
[22] 向青青,蒋建明.个旧地区HIV/AIDS患者生命质量及其影响因素分析[J].中国艾滋病性病,2017,23(10):924-927.
[23] 邹雅琴,朱强,胡秋凌,等.楚雄州HIV感染者生命质量与社会支持状况相关分析[J].皮肤病与性病,2023,45(5):319-323.
[24] 李坚. 自评健康与客观健康的关系[J].暨南大学学报(自然科学与医学版),2001(1):140-142.
[25] FUSTER-RUIZDEAPODACA M J,MOLERO F,HOLGADO F P,et al.Enacted and internalized stigma and quality of life among people with HIV:The role of group identity[J].Qual Life Res,2014,23(7):1967-1975.
[26] WIGINTON J M,MURRAY S,KALL M,et al.HIV-related Stigma and Discrimination in Health Care and Health-related Quality of Life among People Living with HIV in England and Wales:A Latent Class Analysis[J].Stigma Health,2023,8(4):487-496.
[27] SLATER L Z,MONEYHAM L,VANCE D E,et al.The multiple stigma experience and quality of life in older gay men with HIV[J].J Assoc Nurses AIDS Care,2015,26(1):24-35.
[28] NOBRE N,PEREIRA M,ROINE R P,et al.Factors associated with the quality of life of people living with HIV in Finland[J].AIDS Care,2017,29(8):1074-1078.
[29] MALAMA K,LOGIE C H,SOKOLOVIC N,et al.Pathways From HIV-related stigma,racial discrimination,and Gender discrimination to HIV treatment outcomes among women living with HIV in Canada:Longitudinal cohort findings[J].J Acquir Immune Defic Syndr,2023, 94(2):116-123.
[30] 胡晓松,吕华坤,王慎玉,等.文山州HIV/AIDS抗病毒治疗病例艾滋病羞辱和歧视的影响因素分析[J].预防医学,2021,33(3):226-230.
[31] RUEDA S,MITRA S,CHEN S,et al.Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS:A series of meta-analyses[J].BMJ Open,2016,6(7):e11453.
[32] ALSAYED N S,SEREIKA S M,ALBRECHT S A,et al.Testing a model of health-related quality of life in women living with HIV infection[J].Qual Life Res,2017,26(3):655-663.