关键词: 盘膜固相萃取, 气相色谱串联质谱法, 半挥发性有机物, 生活饮用水, 水源水

Abstract:

Objective To establish an analytical method based on disk membrane solid-phase extraction（DMSPE） and gas chromatography-tandem mass spectrometry（GC-MS/MS） for the simultaneous determination of 208 semi-volatile organic compounds（SVOCs） in drinking water and source water. Methods A 1 000 mL water sample was dechlorinated，mixed with 5 mL methanol，and subjected to enrichment and clean-up using DMSPE. The analytes were eluted sequentially with 3 mL of ethyl acetate and 3 mL of dichloromethane，concentrated to near dryness under a nitrogen stream at 40 ℃，and reconstituted in 1 mL of ethyl acetate-dichloromethane（8∶2，V/V）. Separation was performed on an HP-5MS Ultra Inert column（30 m×250 μm×0.25 μm） with electron ionization（EI）. Detection was carried out in dynamic multiple reaction monitoring（dMRM） mode，and quantification was achieved using a working curve method. Results All 208 target compounds were well separated，showing good linearity（r>0.995） within their respective concentration ranges. The method detection limits ranged from 0.012 to 2.200 ng/L，and the quantification limits ranged from 0.047 to 7.400 ng/L. In spiked water samples，the average recoveries of the target compounds were 70.0%-130.0%，with relative standard deviations（RSD） of 0.45%-18.30%. Conclusion The developed method is simple，rapid，and demonstrates high throughput，high sensitivity，good precision，and accuracy. It is suitable for routine monitoring and emergency detection of multiple SVOCs in drinking water and source water.

Key words: Disk membrane solid-phase extraction, Gas chromatography-tandem mass spectrometry, Semi-volatile organic compounds, Drinking water, Source water