关键词: 卤代烃, 静态顶空, 气相色谱三重四级杆串联质谱

Abstract: Objective To establish a method for determination of 13 halohydrocarbon compounds by gas chromatography-triple quadrupole tandem mass spectrometry after static-headspace. Methods 4.00 g sodium sulfate was put into a headspace bottle,and 10 mL water sample was added. After sealing immediately and shaking vigorously,the headspace bottle was placed in the incubator and balanced at 80 ℃ for 25 minutes. Some gas of the bottle was extracted into analyzer,and the target compounds were separated on VF-624MS column（30 m×0.25 mm,1.4 μm）. 13 halohydrocarbon compounds were determined with positive ion electrospray multiple reaction monitoring mode（MRM） and external standard method was used for quantification. Results It was shown that the linear relationship was good：1,2-dichloroethane and tribromomethane in the range of 1.5-300 μg/L,chlorodibromomethane in the range of 0.92-184 μg/L,chlorobromomethane in the range of 0.678-135.6 μg/L,and other halohydrocarbon compounds in the range of 0.5-100 μg/L. The correlation coefficients were all >0.998,and the limits of detection were 0.011-0.066 μg/L. The recoveries were 68.7%-119.5%,and the precisions were 1.1%-9.2%. Conclusion This method is rapid,simple,precise and sensitive,and it is suitable for the determination of 13 halohydrocarbon compounds in water.

Key words: Halohydrocarbon compounds, Static-headspace, Gas chromatography-triple quadrupole tandem mass spectrometry