职业与健康 ›› 2026, Vol. 42 ›› Issue (19): 2713-2716.

• 综述 • 上一篇    下一篇

天津市河东区1起百日咳家庭聚集性疫情的调查

任慧萍1, 李元衡2   

  1. 1 天津市河东区向阳楼街社区卫生服务中心天津 300161
    2 天津市河东区疾病预防控制中心天津 300151
  • 收稿日期:2025-04-29 修回日期:2025-10-23 出版日期:2026-10-01 发布日期:2026-08-17
  • 作者简介:任慧萍,女,副主任医师,主要从事免疫规划工作。

Investigation on a family cluster outbreak of pertussis in Hedong District of Tianjin

REN Huiping1, LI Yuanheng2   

  1. 1 Tianjin Hedong District Xiangyanglou Street Community Health Service CenterTianjin 300161, China
    2 Tianjin Hedong District Center for Disease Control and PreventionTianjin 300151, China
  • Received:2025-04-29 Revised:2025-10-23 Online:2026-10-01 Published:2026-08-17

摘要:

目的 通过对天津市河东区1起百日咳家庭聚集性疫情的调查,查明传染源、分析传播模式,为百日咳防控提供依据。方法 采用描述研究方法,对此次疫情的流行病学调查资料、病例及密切接触者的鼻咽拭子和血清标本的实验室检测结果、免疫史进行分析。结果 该起百日咳家庭聚集性疫情自2023年10月15日—11月5日共持续36天,包含百日咳病例2例,均为实验室确诊病例,传染源为儿童,传播模式为儿童→成人。监测密切接触者3人,其中1人诊断为百日咳病例,家庭二代发病率为33.33%。结论 百日咳病例临床症状不典型可能影响医疗机构对百日咳的诊断,延误百日咳疫情防控。建议加强医务人员对非典型百日咳病例的诊断能力,提高监测报告敏感性。做好重点人群健康教育,探索更优的含百日咳成分疫苗免疫策略,防止百日咳暴发流行。

关键词: 百日咳, 家庭, 聚集, 调查

Abstract:

Objective To identify the source of infection and analyze the mode of transmission through the investigation and analysis of a family cluster epidemic of pertussis in Hedong District of Tianjin,so as to provide evidence for the prevention and control of pertussis. Methods Descriptive methods were used to analyze the epidemiological investigation data,nasopharyngeal swabs and serum samples of cases and close contacts,and immunization history of this epidemic. Results The family cluster outbreak lasted for 36 days from October 15 to November 5,2023,contained 2 cases of pertussis,all of which were laboratory-confirmed cases. The source of infection was children and the mode of transmission was from children to adults. Three close contacts were monitored,one of whom was diagnosed with pertussis,and the second-generation incidence rate was 33.33%. Conclusion Atypical clinical symptoms of pertussis cases may affect the diagnosis of pertussis in medical institutions and delay the prevention and control of pertussis epidemic. It is recommended to strengthen the diagnostic capacity of medical staff for atypical pertussis cases and improve the sensitivity of surveillance reports. Health education for key populations should be done well to explore better immunization strategies for vaccines containing pertussis components to prevent outbreaks of pertussis.

Key words: Pertussis, Family, Cluster, Investigation

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