关键词: 三嗪类除草剂, 固相萃取, Supelclean ENVI-Chrom P SPE小柱, 超高液相色谱-串联质谱, 内标法, 生活饮用水

Abstract:

Objective To establish a ultra-high performance liquid chromatography-tandem mass spectrometry（SPE-UPLC-MS/MS） method for the determination of 12 triazine herbicides in drinking water. Methods Water samples were spiked with internal standards and extracted using Supelclean ENVI-Chrom P SPE cartridges，followed by detection via UPLC-MS/MS. Quantification was performed using the internal standard method. Results The 12 triazine herbicides exhibited good linearity in the range of 0.1 to 50.0 ng/mL（r≥0.999）. With a sample volume of 200 mL，the method detection limits（MDLs） for the 12 triazine herbicides ranged from 0.05 to 0.14 ng/L，and the method quantification limits（MQLs） ranged from 0.15 to 0.42 ng/L. For the three concentration levels（5，50，and 200 ng/L），the spike recovery rates ranged from 83.6% to 101.1% in pure water and from 85.6% to 100.4% in tap water. The relative standard deviations（RSDs） were 1.1%-4.3% and 1.0%-6.0%，respectively. Conclusion The established method is sensitive，reliable，and suitable for the detection of 12 triazine herbicides in drinking water.

Key words: Triazine herbicides, Solid-phase extraction, Supelclean ENVI-Chrom P SPE cartridges, Ultra-high performance liquid chromatography-tandem mass spectrometry, Internal standard method, Drinking water