Objective To explore the relationship between mental health literacy and job burnout among internet employees,as well as the mediating role of a health-promoting lifestyle and the moderating role of the work environment. Methods In October and November 2024,a questionnaire survey was conducted on 636 internet employees from 27 provinces in China. The survey used the mental health literacy scale(MHLS),Maslach burnout inventory-general survey(MBI-GS),health promoting lifestyle profile 2nd edition revised(HPLP-Ⅱ R),and perceived work environment scale,followed by data analysis. Results Internet employees scored a mean of (3.17±0.30)points on mental health literacy,(3.71±0.45)points on health-promoting lifestyle,(2.80±0.94)points on job burnout,and (4.07±0.42)points on work environment. Mental health literacy had a significant direct predictive effect on job burnout(β=-0.360,P<0.01). After including the health-promoting lifestyle,the direct predictive effect of mental health literacy on job burnout remained significant(β=-0.239,P<0.01),and the health-promoting lifestyle had a statistically significant mediating effect on job burnout(β=-0.383,P<0.01),with the mediating effect accounting for 33.70% of the total effect value. The work environment had a positive moderating effect on the first half of the mediating model path(β=0.129,P<0.01). Conclusion The mental health literacy among internet workers is significantly and negatively correlated with job burnout,and mental health literacy indirectly affects job burnout through a health-promoting lifestyle. The work environment has a moderating effect on the first half of the model path,meaning that a good work environment enhances the relationship between mental health literacy and a health-promoting lifestyle. This finding emphasizes that improving mental health literacy,promoting a healthy lifestyle,and optimizing the work environment are important strategies for effectively alleviating job burnout.