Table of Content

01 June 2025, Volume 41 Issue 11

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Treatise

Application of three risk assessment methods in occupational health risk assessment of dust operation posts in cement manufacturing enterprises in Dalian City

SHAO Xiaocui, WANG Yanyan, LIU Shuang

2025, 41(11):  1441-1445. 

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Objective To evaluate the occupational health risks of dust operation posts in cement manufacturing enterprises in Dalian using three risk assessment methods,and to explore the applicability of different risk assessment methods for occupational health risk assessment of dust operation posts in the cement industry. Methods Seven cement manufacturing enterprises in Dalian with similar production processes were selected from 2019 to 2023. The semi-quantitative contact ratio method,semi-quantitative comprehensive index method,and International Council on Mining and Metals（ICMM） occupational health risk assessment quantitative method were employed to evaluate the occupational health risks of dust operation posts. Wilcoxon signed-rank test was used to test for differences among three evaluation methods,and Spearman rank correlation analysis was used for correlation analysis. Results A total of 35 dust operation posts and 194 dust samples were collected from the seven cement manufacturing enterprises. The test results indicated that the presence of limestone dust,silica dust,coal dust,and cement dust in the dust operation posts. The total dust concentration was 0.70-21.13 mg/m³,and respirable dust concentration was 0.37-11.60 mg/m³. No statistical differences were found in the occupational health risk levels of total dust and respirable dust among different positions between the semi-quantitative contact ratio method and the semi-quantitative comprehensive index method（P>0.01）. There were statistically significant differences among the results of the three risk assessment methods（P<0.01）. The evaluation results of the three risk assessment methods were positively correlated（P<0.01）,with the highest correlation between the semi-quantitative contact ratio method and the semi-quantitative comprehensive index method. Conclusion The semi-quantitative contact ratio method and the semi-quantitative comprehensive index method shows good consistency in assessing the occupational health risks of total dust and respirable dust in various positions. Among the three risk assessment methods,the semi-quantitative composite index method has the highest evaluation results,while the ICMM quantitative method has the lowest results. For dust operation posts with low dust concentrations and shorter exposure time,the semi-quantitative comprehensive index method is more applicable. For dust operation posts with higher dust concentrations but shorter exposure time,the ICMM quantitative method is more suitable.

Impact of instant messaging overload and job reshaping behavior on occupational burnout among obstetric and gynecological nurses

YE Jianhua, WU Zhenzhen, FANG Min, CHEN Haiyan, XIE Maohua, WANG Jing

2025, 41(11):  1446-1450. 

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Objective To understand the status of instant messaging overload,job reshaping behavior,and occupational burnout among obstetric and gynecological nurses,and to explore the impact of instant messaging overload and job reshaping behavior on occupational burnout. Methods From January to February 2024,a simple random sampling method was used to survey the obstetrics and gynecology nurses in 8 comprehensive hospitals in Wuhan using the instant messaging overload scale,job reshaping load scale,and occupational burnout load scale. Results The instant messaging overload score of obstetrics and gynecology nurses was （18.42±3.84）points,job reshaping score was （82.40±10.34）points,and occupational burnout score was （60.18±9.37）points. Obstetrics and gynecology nurses' instant messaging overload,job reshaping,and occupational burnout were related to age,working years,professional title,monthly income,and number of night shifts per month（all P<0.05）. There was a positive correlation between instant messaging overload and occupational burnout among obstetric and gynecological nurses（r=0.622,P<0.01）,a negative correlation between job reshaping and occupational burnout（r=-0.596,P<0.01）,and a negative correlation between instant messaging overload and job reshaping（r=-0.572,P<0.01）. Job reshaping of obstetric and gynecological nurses partially mediated the relationship between instant messaging overload and occupational burnout,with a mediation effect of 0.276,accounting for 48.25% of the total effect. Conclusion Instant communication overload and job reshaping among obstetrics and gynecology nurses are closely related to occupational burnout. Job reshaping plays a partial mediating role between instant communication overload and occupational burnout. Reducing instant communication overload and improving job reshaping levels are beneficial for reducing occupational burnout levels.

Mediating role of ego depletion in the relationship between negative gossip in the workplace and job burnout among respiratory nurses

HU Yanling, WU Jing, CHEN Xiaoxue, YU Donglin, YANG Shenfan, TAN Fen

2025, 41(11):  1451-1455. 

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Objective To explore the mediating role of ego depletion in the relationship between negative gossip in the workplace and job burnout among respiratory nurses. Methods The random number table method was used to randomly select 185 nurses from the respiratory departments of 6 tertiary general hospitals in Wuhan from January to March 2024 as the survey subjects. The general situation scale,negative gossip scale,ego depletion scale,and job burnout scale were used for the survey. Univariate analysis was used to compare the differences in negative gossip,ego depletion,and job burnout among different demographic characteristics,spearman rank correlation was used to analyze the correlation between negative gossip,ego depletion,and job burnout. Results The scores of negative gossip in the workplace,ego depletion and job burnout of respiratory nurses were （9.14±2.46）,（12.46±2.75） and （61.52±12.42）points,respectively. The negative gossip score of respiratory nurses in the workplace was positively correlated with the job burnout score（r=0.615,P<0.01）,the ego depletion score was positively correlated with the job burnout score（r=0.559,P<0.01）,and the negative gossip score in the workplace was positively correlated with the ego depletion score（r=0.582,P<0.01）. Ego depletion played a positive mediating effect between negative gossip and job burnout of respiratory nurses,with an effect value of 0.321,accounting for 39.48% of the total effect. Conclusion Negative gossip in the workplace is positively correlated with job burnout among respiratory nurses. Ego depletion plays a partial mediating role in the relationship between negative gossip in the workplace and job burnout. Reducing the spread of negative gossip in the workplace and reducing ego depletion of psychological resources are conducive to reducing the level of job burnout.

Analysis on impact of verbal violence on occupational burnout in outpatient nurses and the multiple mediating effects of caring ability and emotional intelligence

SONG Ping, ZHAN Hui, CHEN Xian, WANG Xiuping, ZHANG Zhongying

2025, 41(11):  1456-1461. 

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Objective To investigate the multiple mediating effects of caring ability and emotional intelligence on the relationship between verbal violence encountered by outpatient nurses and their professional burnout. Methods A convenience sampling method was used to select 394 outpatient nurses from 12 public hospitals of different levels in Jiangsu Province from June to August 2023 as research subjects. Data collection was conducted using a general information questionnaire,an outpatient workplace verbal violence questionnaire,caring ability inventory scale,Wong and Law emotional intelligence scale,and occupational burnout scale. Structural equation modeling was applied to analyze the mediating role of care capability and emotional intelligence between verbal violence encountered by outpatient nurses and occupational burnout. Results 110 outpatient nurses（27.92%） reported experiencing verbal violence at work in the past month. The total score of care ability,emotional intelligence and occupational burnout for outpatient nurses in 12 different levels of public hospitals in Jiangsu Province were （181.51±24.06）,（68.31±16.97）,and（135.57±24.22）points,respectively. There was a significant positive correlation between verbal violence suffered by outpatient nurses and occupational burnout（r=0.370,P<0.05）. Care capability and emotional intelligence played a partial mediating role in the relationship between verbal violence and nursing burnout,with mediating effects of 9.77% and 32.65%,respectively. Conclusion Care capability and emotional intelligence play an important mediating role in alleviating the relationship between verbal violence and occupational burnout,with the mediating effect of emotional intelligence being more significant. Enhancing the care capability and emotional intelligence capabilities of outpatient nurses can help reduce the occupational burnout caused by verbal violence,effectively improve doctor-patient relationships,enhance nursing service quality,and increase nurses' job satisfaction.

Effects and mechanisms of occupational mercury exposure on fibrosis in human hepatic stellate cell line（LX-2）

SUN Pengpeng, ZHOU Tao

2025, 41(11):  1462-1468. 

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Objective To explore the effect of occupational mercury exposure on fibrosis in human hepatic stellate cell line（LX-2） based on the microRNA-143-3p（miR-143-3p）-angiopoietin-like protein 8（ANGPTL8） pathway. Methods Human hepatic stellate cells LX-2 were digested with trypsin and plated in a 96-well plate at 4×10³ cells/well. After incubation for 24 hours,different concentrations of HgCl₂（0,100,200,400 μmol/L） were added. The cells were incubated for 72 hours,the cell proliferation level,the number of monoclonal formation,the apoptosis level,and the G2/M phase of the cell cycle were measured. The cell fibrosis indicators α-smooth muscle actin（α-SMA） and type collagen A1（Col1a1） were determined by immunofluorescence assay,the levels of inflammatory indicators tumor necrosis factor alpha（TNF-α）,interleukin-6（IL-6）,and interleukin-18（IL-18） were measured by enzyme-linked immunosorbent assay,and the levels of cellular miR-143-3p and ANGPTL8 were measured by RT-PCR and Westen-blot methods. Results Compared with the control group（0.00 μmol/L HgCl₂）,the survival rate,number of monoclonal formations,and levels of fibrosis indicators α-SMA and Col1a1 in the exposure dose groups of 2.50,5.00,and 10.00 μmol/L HgCl₂ were significantly increased（all P<0.01）,while apoptosis rate and cell cycle G2/M phase levels were significantly reduced（all P<0.01）. With the increase of HgCl₂ exposure dose,the survival rate,the number of monoclonal formation,and the levels of fibrosis indicators α-SMA and Col1a1 in each dose group of HgCl₂ gradually increased（all P<0.01）,and the apoptosis rate and cell cycle G2/M phase levels gradually decreased（all P<0.01）. Compared with the control group（0.00 μmol/L HgCl₂）,the expression levels of miR-143-3p in the exposure dose groups of 2.50,5.00 and 10.00 μmol/L HgCl₂（4.83±0.87 vs 2.92±0.62,1.91±0.34,0.85±0.10）were significantly reduced（all P<0.01）,while the expression levels of ANGPTL8 mRNA protein（0.95±0.11 vs 1.59±0.16,2.84±0.29,3.69±0.38;0.23±0.06 vs 0.46±0.12,0.83±0.17,1.49±0.21）,TNF-α,IL-6,and IL-18 increased significantly（all P<0.01）. With the increase in HgCl2 exposure dose,the expression levels of miR-143-3p in each dose group of HgCl₂ gradually decreased（2.92±0.62 vs 1.91±0.34 vs 0.85±0.10）,while the expression levels of ANGPTL8 mRNA protein（1.59±0.16 vs 2.84±0.29 vs 3.69±0.38,0.46±0.12 vs 0.83±0.17 vs 1.49±0.21）,TNF-α,IL-6 and IL-18 gradually increased（all P<0.01）. Conclusion Mercury exposure can promote abnormal proliferation of human hepatic stellate cell line（LX-2）,induce fibrosis progression,inhibit cell apoptosis,and induce cell cycle arrest. The mechanism is related to the inhibition of miR-143-3p expression in human hepatic stellate cell line（LX-2） by mercury exposure,which in turn promotes high expression of ANGPTL8.

Exploring the protective effect of resveratrol on aluminum induced cranial nerve injury in rats based on the NLRP3-NF-κB-MMP-9 pathway

ZHANG Bo, SHI Yong

2025, 41(11):  1469-1476. 

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Objective To explore the protective effect of resveratrol on aluminum induced cranial nerve injury in rats based on the nod-like receptor family pyrin domain containing 3（NLRP3）- nuclear factor kappa-beta（NF-κB）- metalloproteinase 9（MMP-9） pathway. Methods Totally 40 adult rats were divided into a normal control group,an aluminum exposure group,and resveratrol low-dose and high-dose groups（100 and 200 mg/kg）. Rats in the aluminum exposure group and the low-dose and high-dose resveratrol group were exposed to aluminum trichloride to establish a model of cranial nerve function injury. During the exposure period,the rats in the low-dose and high-dose resveratrol groups were given daily resveratrol gavage intervention,while the normal control group and the aluminum exposure group were given an equal volume of normal saline. After the experiment,neurological function indicators,blood-brain barrier leakage level,neuronal apoptosis levels in brain tissue,brain tissue NLRP3,NF-κB,MMP-9 mRNA protein expression levels,tumor necrosis factor-α（TNF-α）,interleukin-1 beta（IL-1β）,nitric oxide synthase（iNOS） levels. Results Compared with the normal control group,the aluminum exposure group showed an increase in neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,NLRP3,NF-κB,and MMP-9 mRNA protein levels in cranial tissue（0.86 ±0.09 vs 3.58±0.29,0.75± 0.08 vs 4.20±0.22,0.97± 0.06 vs 4.12±0.18, 0.29± 0.05 vs 1.74± 0.19,0.38±0.07 vs 1.86± 0.18,0.34±0.08 vs 1.79±0.20）, as well as an increase in levels of inflammatory factors TNF-α, IL-1β, and iNOS in cranial tissue,and a decrease in the number of crossing the original platform position,and the differences were statistically significant（all P<0.05）. Compared with the aluminum exposure group,resveratrol low-dose and high-dose groups neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,cranial tissue NLRP3,NF-κB,MMP-9 mRNA protein levels（3.58±0.29 vs 2.68±0.19,1.62±0.13,4.20±0.22 vs 2.55±0.17,1.72±0.17,4.12±0.18 vs 3.14±0.13,2.01±0.10;1.74±0.19 vs 1.04±0.13,0.73±0.10,1.86±0.18 vs 1.53±0.16,1.02±0.10,1.79±0.20 vs 1.27±0.18,0.74±0.11）,cranial tissue inflammatory factor TNF-α,IL-1β,and iNOS levels decreased,and the number of crossing the original platform position increased,the differences were statistically significant（allP <0.05）. Compared with the resveratrol low-dose group, the resveratrol high-dose group showed a decrease in neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,cranial tissue NLRP3,NF-κB,MMP-9 mRNA protein levels and cranial tissue inflammatory factors TNF-α,IL-1β,iNOS levels,an increase in the number of crossing the original platform position,and the differences were statistically significant（all P<0.05）. Conclusion Resveratrol has a significant therapeutic effect on aluminum exposure induced cranial nerve injury in rats,and its mechanism is related to the inhibition of NLRP3,NF-κB,and MMP-9 mRNA protein expression induced by aluminum exposure,thereby inhibiting the activation of the NLRP3-NF-κB-MMP-9 pathway.

UPLC-Q-TOF rapid qualitative and quantitative screening for an aconitum poisoning event

KOU Jinchan, SUN Mingyue, ZHOU Rongui, LIN Ji

2025, 41(11):  1477-1482. 

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Objective To conduct an epidemiological investigation on a suspected case of aconitine poisoning in Shilin County of Yunnan Province,and to perform rapid qualitative and quantitative detection of aconitine compounds in the collected samples. Methods On December 27,2023,a mass food poisoning incident occurred in Shilin County of Yunnan Province,and on January 2,2024,the Yunnan Center for Disease Control and Prevention received the samples and extracted the aconitine compounds in the samples by ultrasonic extraction,and used ultra-performance liquid chromatography tandem mass spectrometry to select C₁₈（2.1 mm×100 mm,1.8 μm） chromatography column in positive mode for substance separation. Methyl cyanide（B） and 5 mmol/L ammonium acetate-0.1% methane acid water（A） were selected as gradient elution mobile phases,with a column temperature of 40 ℃ and a flow rate of 0.3 mL/min. The precise molecular weight and secondary mass spectrometry of each substance were used for rapid screening of leftover food,blood,and urine. Results In the concentration range of 5.0-500 ng/mL,the linear correlation coefficients of 13 standards were all greater than 0.993,and the relative standard deviation（RSD） of stability was ≤2.44%. The recovery rates of the three samples under spiked conditions were between 75.4%-111.9%,and the RSD of precision was ≤2.88%. Benzoyl hypoaconitine,benzoyl neoaconitine,benzoyl aconitine,Yunnan aconitine and oxaconitin were detected in the leftover meals,with concentrations of 0.21,0.33,0.60,0.20,and 5.31 mg/kg,respectively. Conclusion The poisoning incident was caused by excessive consumption of aconitine stew soup. This detection method has high sensitivity and good stability,and is suitable for the detection of toxins in aconitum plants.

Effects of occupational exposure to styrene on proliferation,invasion,apoptosis and cell cycle of leukemia cell line HL-60

YANG Jin

2025, 41(11):  1483-1488. 

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Objective To explore the effect of occupational exposure to styrene on the proliferation,invasion,apoptosis and cell cycle of leukemia cell line HL-60 based on the miR-126-CSE1L pathway. Methods The leukemia cell line HL-60 in the logarithmic growth phase was exposed to styrene solutions of 0,10,20,and 40 nmoL/mL for 72 h. After culture,the cell viability and cell colony levels were measured using CCK-8 kit and crystal violet staining. Flow cytometry was used to measure cell cycle and apoptosis levels,Transwell assay was used to measure cell invasion levels,and RT-PCR and western blot methods were used to measure cellular miR-126 and CSE1L levels. Results After the leukemia cell line HL-60 was treated with styrene at doses of 10,20,and 40 nmoL/mL,the survival rate,cell colony,invasion,and CSE1L mRNA protein expression levels（0.68±0.18 vs 1.18±0.17,1.51±0.15,2.75±0.11;0.26±0.12 vs 0.50±0.11,0.79±0.14,1.24±0.18） were significantly higher than those in the control group,G2/M phase,apoptosis rate,and miR-126 expression level（2.97±0.20 vs 2.24±0.19,1.65±0.14,0.85±0.13） were significantly lower than those in the control group,and the differences were statistically significant（all P<0.05）. The survival rate,cell colony,invasion,and CSE1L mRNA protein expression levels（1.18±0.17,1.51±0.15,2.75±0.11,0.50±0.11,0.79±0.14,1.24±0.18） gradually increased in the styrene exposure dose groups of 10,20,and 40 nmoL/mL,while the G2/M phase,apoptosis rate,and miR-126 expression levels（2.24±0.19,1.65±0.14,0.85±0.13） gradually decreased. Styrene increased the survival rate,cell colonies,G2/M phase,invasion,and CSE1L mRNA protein expression levels in each group in a dose-dependent manner,while reduced G2/M phase,apoptosis rate,and miR-126 expression levels in each group,and the differences were statistically significant（all P<0.05）. Conclusion Styrene can promote the proliferation and invasion of leukemia cell line HL-60,inhibit apoptosis,and induce cell cycle arrest. The mechanism may be related to the inhibition of miR-126 levels in leukemia cell line HL-60 by styrene,which in turn targets the up-regulation of CSE1L expression.

Study on current situation and influencing factors of occupational compromise among 398 cardiothoracic surgery nurses in Sichuan Province

LIU Huan, LIU Ying

2025, 41(11):  1489-1494. 

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Objective To investigate the current situation of career compromise of cardiothoracic surgery nurses in Sichuan Province,and analyze its influencing factors,in order to provide theoretical basis for formulating targeted intervention strategies. Methods From March to April 2024,purposive sampling was used to select nurses from the cardiothoracic surgery departments of 14 tertiary comprehensive hospitals in Sichuan Province as the research subjects. General information questionnaire,career compromise scale,career outlook scale,and inclusive leadership scale were used for the survey,and the data were analyzed. Results The professional compromise score of 398 cardiothoracic surgery nurses in Sichuan general hospital was （45.72±6.61）points, the inclusive leadership score was （30.21±6.58）points,and the professional development score was （121.00±18.08）points. The results of univariate analysis showed that there were statistically significant differences in career compromise scores among cardiothoracic nurses of different genders,ages,educational backgrounds,professional titles,monthly income,whether they had clear career plans,and whether they were willing to engage in cardiothoracic nursing work（all P<0.05）. The correlation analysis results showed that inclusive leadership of nurses in cardiothoracic surgery was positively correlated with occupational development concept,and negatively correlated with occupational compromise, the career development concept was negatively correlated with career compromise（all P<0.05）. The results of the multivariate analysis showed that whether there was a clear career plan,age,gender,willingness to engage in cardiothoracic nursing working,occupational development outlook and inclusive leadership entered the regression equation,which could explain 78.0% of the total variation（all P<0.05）. Conclusion The occupational compromise of cardiothoracic surgery in Sichuan Province is above the medium level. Nurses who lack clear career planning,are older,more male,less willing to engage in cardiothoracic nursing work,have lower scores in career development concepts,and have lower scores in inclusive leadership tend to have more severe professional compromise. Managers should adopt targeted intervention strategies to enhance nurses' occupational development concept and inclusive leadership perception,thereby reducing their level of professional compromise and enabling them to better engage in their work.

Construction of an evaluation index system for job competency of Dai medical talents

JIANG Xiaoli, ZHANG Chao, YANG Liping, LUO Shihua, DUAN Xiaohua

2025, 41(11):  1495-1501. 

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Objective To construct an evaluation index system of job competency for Dai medical talents,and to provide a reference for the cultivation,appointment,and evaluation of Dai medical talents. Methods For January 2023 to April 2024,the literature analysis method was used to collect the indicators related to Dai medicine and job competence through semi-structured interviews with selected Dai medical specialists. The results of the semi-structured interviews were discussed and analyzed with the results of the literature analysis to construct the preliminary item pool of the evaluation index system of Dai medicine talents' job competence,and formulated the experts' correspondence form. Through the Delphi expert consultation,the index screening,entry addition,deletion,and modification were carried out on the recovered correspondence form,and the entry weights were analyzed and calculated by the hierarchical analysis method to determine and improve the construction of the evaluation index system of Dai medical talents' job competency,and finally,the credibility test was carried out on the evaluation system. Results Literature analysis method and semi-structured interviews initially formulated 4 first-level indicators and 44 second-level indicators of competency for Dai medicine positions. After two rounds of expert correspondence were conducted with 15 experts,the recovery rates of the two rounds of expert correspondence questionnaires were 100.00% and 80.00%,and the authority coefficients were 0.8 and 0.828,respectively. The Kendall's coefficients of the first level and second level entries were 0.279（χ²=15.345,P>0.09） and 0.225（χ²=145.050,P<0.01） in the first round,and 0.333（χ²=15.000,P<0.05） and 0.277（χ²=146.353,P<0.01） in the second round,and finally formed 6 first-level indicators and 49 second-level dimensions of Dai medicine job competency,and weight analysis was conducted. Conclusion This study constructs the evaluation index system for job competency of Dai medical talents,which provides a reference for the cultivation of Dai medical talents and the construction of the Dai medical team.

Research on subjective life expectancy and influencing factors of the elderly in China based on CHARLS data

TIAN Liudan, WU Hongyan, YANG Xing, YU Jiangxi, LI Xingchen, RONG Yi

2025, 41(11):  1502-1507. 

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Objective To understand the subjective estimates of life expectancy of the elderly over 60 years old in China and its influencing factors,so as to provide reference for individuals,society,and decision-making departments to effectively improve life expectancy. Methods Individuals aged 60 and above of the China health and retirement longitudinal study（CHARLS） in 2013, 2 015,and 2018 were selected to analyze the subjective life expectancy（SLE） and its influencing factors of the elderly in China by a fixed-effects ordered logit model,and analyzed the heterogeneity between elderly people of different genders. Results A total of 2987 elderly people were included in the study. Overall,from 2013 to 2018,the proportion of "virtually certain" and "very likely" of SLE declined,with "virtually certain" declining even more,from 22.60% to 10.91%. The proportion of "almost impossible" and "unlikely" of SLE showed an upward trend,with "almost impossible" showing a larger increase from 13.83% to 23.97%. Although the proportion of "likely" had decreased,the overall trend was still on the rise. The SLE was lower for older persons with chronic diseases,hospitalization due to illness in the past year,depression,and poor self-assessed health,and higher for those who were covered by basic health insurance,smoked,had one living parent,and participated in social activities. Conclusion It is suggested that the care for the elderly should be strengthened at the social,family and individual levels. By meeting the physical and mental health needs of the elderly,the goal of improving their life expectancy can be achieved.

Analysis of mortality trend and probability of premature mortality of cancers in Chongming District of Shanghai from 2005 to 2022

SHI Aiyu, GU Tianyi, XU Yan, HUANG Yuhua, SUN Xiaolei

2025, 41(11):  1508-1514. 

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Objective To understand the mortality trend and the probability of premature mortality of cancers in Chongming District of Shanghai,and to provide basis for reducing the probability of premature mortality and achieving the goal of controlling the probability of premature mortality. Methods Collect cancer death data of registered residents in Chongming District of Shanghai from 2005 to 2022,calculate crude mortality rate,standardized mortality rate,the probability of premature mortality and other indicators of cancer,and use annual percentage of change（APC） and average annual percentage of change（AAPC） to reflect the change trend of crude mortality rate,standardized mortality rate and probability of premature mortality. Results From 2005 to 2022,the crude mortality rate of cancer among registered residents in Chongming District of Shanghai was 274.38/10⁵,the standardized mortality rate was 97.93/10⁵. The male crude mortality rate was 353.88/10⁵,the male standardized mortality rate was 133.88/10⁵. The female crude mortality rate was 197.25/10⁵,the female standardized mortality rate was 66.79/10⁵. The rude mortality rate of mortality,male and female showed an upward trend（APC_totle=2.22%,APC_male=2.20%,APC_female=2.15%,all P<0.01）,while the standardized mortality rates showed a downward trend（APC_totle=-1.51%,APC_male=-1.74%,APC_female=-1.39%,all P<0.01）. The standardized mortality rate of male colorectal cancer showed an upward trend among various cancers（AAPC=3.57%,P<0.01）,the standardized mortality rate of female cervical cancer showed an upward trend（APC=5.32%,P<0.05）. The probability of premature mortality of cancer was 6.39%,the male was 8.36%,the female was 4.46%. The probability of premature mortality of overall population,male and female showed a downward trend（APC_totle=-2.40%,APC_male=-2.42%,APC_female=-2.27%,all P<0.01）. Lung cancer, liver cancer,and gastric cancer were the top three probabilities of premature mortality in men and women. The probability of premature mortality of top ten cancers for males with lung cancer,liver cancer,gastric cancer,esophageal cancer showed a decreasing trend（all P<0.05）,while for females with gastric cancer,liver cancer,brain and central nervous system,and leukemia showed a decreasing trend（all P<0.05）. Conclusion The crude mortality rate of cancer showed an upward trend,and the standardized mortality rate and the probability of premature mortality showed a decreasing trend. The standardized mortality rate of male colorectal cancer and female cervical cancer is on the increase. The probability of premature mortality of colorectal cancer and pancreatic cancer in male and female,lung cancer,breast cancer,cervical cancer,and ovarian cancer in female are not on the decline. Targeted prevention and control measures should be taken to reduce the mortality and the probability of premature mortality.

Analysis on trend of changes in rural drinking water quality in Huai'an City from 2008 to 2022

YANG Juan, CHEN Xiaomin, CHEN Guocai, LUO Shancai, ZHANG Wen

2025, 41(11):  1515-1519. 

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Objective To analyze the trend of changes in rural drinking water quality in Huai'an City from 2008 to 2022,and provide reference for further improving the safety level of rural drinking water in Huai'an area. Methods Collect monitoring data of rural drinking water in Huai'an City from 2008 to 2022,analyze the qualified rate and the change trend of water quality. Results From 2008 to 2022,a total of 23 501 rural drinking water samples were monitored in Huai'an City,with an overall qualified rate of 88.9%. The qualified rate of rural drinking water ranged from 84.3% to 100.0% from 2008 to 2022,which showed an overall upward trend（P<0.05）. The main unqualified items included the total coliform bacteria,total colony,heat-resistant coliforms, turbidity,visible substances,manganese,iron,etc.,and the qualified rate of the items showed an upward trend（P<0.05）,the overall content of the items showed a downward trend（P<0.05）. However,the oxygen consumption value had been continuously increasing since 2017（P<0.05）,while indicators such as chloride,sulfate,soluble total solid,and total hardness had shown an upward trend since 2022. Conclusion From 2008 to 2022,the overall qualification rate of rural drinking water in Huai'an City showed an upward trend,and the water quality was significantly improved,which is related to the effective implementation of regional centralized water supply strategies. However,after the overall decrease in some indicators,they have shown an upward trend in recent years,which is worth paying attention to.

Network analysis of internet gaming disorder and emotional issues among 2022 cohort students of Tianjin Public Security Profession College

LI Boxiang, SHANG Xin, LIU Ning, JIA Fei

2025, 41(11):  1520-1525. 

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Objective To understand the relationship between internet gaming disorder（IGD） and emotional problems among 2022 freshmen at Tianjin Public Security Profession College,and to expand the application of the Chinese version of the ten-item internet gaming disorder test（IGDT-10） in China. Methods In October 2022,a cluster sampling method was used to select the 2022 freshmen of Tianjin Public Security Profession College as the study subjects. The Chinese version of IGDT-10 and the Chinese version of depression anxiety stress scale（DASS-21） were administered to 987 students. Network analysis was employed to construct and analyze the network relationship model among factors. Results The prevalence of IGD was 15.00%. In the high-risk group,the weight between "giving up activities" and "negative consequences 1",as well as between "persistent use" and "negative consequences 2",was the highest（both 0.52）. In the low-risk group,the weight between "preoccupation" and "escape" was higher（0.32）. "Loss of control" had the highest centrality indicator in the high-risk group. Depression（r=0.57）,anxiety（r=0.51）,and stress（r=0.48） were all significantly positively correlated with IGD（all P<0.01）. Conclusion The cutoff criteria for IGD supported by the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition（DSM-5）,are more conservative compared to the latent profile analysis method. It is suggested that interventions for college students with IGD should focus more on self-control and the restoration of interpersonal relationships.

Mediating effect of clinical belongingness on aversion and professional identity among nursing students

CUI Qiuyue, GUI Yuxin, ZHONG Ying, MA Shuai, GE Yuan

2025, 41(11):  1526-1530. 

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Objective To understand the current status of nursing students' aversion,clinical belongingness,and professional identity,and explore the mediating effect of clinical belonging between aversion and professional identity of nursing students. Methods Convenience sampling method was used to select 282 nursing students from three institutions of higher learning in Guangxi Zhuang Autonomous Region from December 2023 to February 2024 as the study subjects. The general information questionnaire,Chinese version of aversion scale,clinical sense of belonging scale,and nurses' professional identity scale were used to conduct the survey,and the data were analyzed. Results Totally 282 nursing students' aversion,clinical belongingness,and professional identity scores was （46.02±10.82）,（90.00±16.40） and （86.06±15.06）points,respectively. The nursing students' aversion was negatively correlated with clinical belongingness and professional identity（r=-0.455,-0.441,both P<0.01）,while clinical belongingness was positively correlated with professional identity（r=0.531,P<0.01）. Clinical sense of belonging partially mediated the relationship between aversion and professional identity,with a mediation effect accounting for 43.07% of the total effect and a 95%CI of -0.328 to -0.160. Conclusion Nursing educators and administrators should intervene in the aversion of nursing students to strengthen the cultivation of clinical belongingness,which in turn enhances their professional identity and promotes the development of the nursing industry.

Study on the infection status and influencing factors of Mycobacterium tuberculosis among close contacts of schools in Pudong New Area of Shanghai from 2019 to 2022

CUI Yanwen, CHEN Lili, XU Min, JIANG Yue, XIAO Shaotan, LI Shihong

2025, 41(11):  1531-1535. 

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Objective To investigate the situation and influencing factors of Mycobacterium tuberculosis infection in student close contacts with pulmonary TB patients among schools in Pudong New Area of Shanghai from 2019 to 2022,so as to provide reference for subsequent tuberculosis screening and prevention and control strategies in schools with low tuberculosis epidemic areas. Methods The purified protein derivative test（PPD）,interferon-γ release assay（IGRA） and/or X-ray chest radiography and questionnaire were carried out among the student close contacts of school TB patients in Pudong New Area of Shanghai from 2019 to 2022. The influencing factors of Mycobacterium tuberculosis infection among close contacts in schools were analyzed by univariate analysis and logistic regression model. Results After screening 6 422 close contacts of the school,31 confirmed cases of pulmonary tuberculosis were found,accounting for 0.48%,and 485 cases of Mycobacterium tuberculosis infection were found,accounting for 7.55%. Logistic regression showed that the risk factors of tuberculosis infection in student close contacts included central source of students[OR（95%CI）=1.530（1.163-2.013）],western source of students[OR（95%CI）=2.029（1.569-2.623）],universities and technical secondary schools[OR（95%CI）=4.719（1.132-19.670）] and previous exposure to tuberculosis[OR（95%CI）=2.220（1.349-3.652]. The index cases identified by health examination[OR（95%CI）=0.560（0.380-0.824）] was a protective factor for close contacts of tuberculosis in schools. Conclusion It is necessary to strengthen the medical observation of college close contacts. At the same time,the school should focus on the health of students from the high epidemic area,strengthen the school entrance and routine physical examination,in order to early detect the TB cases on campus,and reduce the campus transmission.

Visualization analysis of research hotspots in the field of military training load

WANG Jingyi, MA Qiang, WANG Jing, LI Chao, LI Zhe

2025, 41(11):  1536-1544. 

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Objective To present the research topics and hotspots in the field of military training load,analyze research progress and trends,and provide reference for scientific training and improving training quality and efficiency. Methods The core database of Web of Science core collection were used as data sources,bibliometric tools such as VOSviewer,CiteSpace were used for visualization analysis,and the retrieval time was from the establishment of the database to December 31,2023. Results A total of 1 670 core papers were included,with a general upward trend in the number of publications. The country with the strongest comprehensive research strength was the United States,the US Army Research Institute of Environmental Medicine was the institution with the highest number of publications（47 articles）,and Finnish scholar KYROLAINEN was the most prolific author（23 articles）. High frequency keywords include "performance""strength""risk factors" and "fitness",etc. Conclusion The popularity of military training load research continues to increase,with research hotspots includes training load monitoring and quantitative evaluation,training program optimization and effectiveness evaluation,training injury investigation and prevention measures. In the future,we should focus on interdisciplinary integration and cross team communication,strengthen research on training load evaluation systems,stress generation mechanisms,and diagnostic criteria for injuries.

Comparison between sputum induction and self-expectoration samples in the positive detection rates of Mycobacterium tuberculosis based on mete-analyses

ZHANG Xiaoyi, HAN Feng, ZHANG Zhe

2025, 41(11):  1545-1551. 

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Objective To explore whether the use of induced sputum technique has an advantage over self-expectoration on the positive detection rate of Mycobacterium tuberculosis through sputum smears,molecular biology techniques and sputum culture methods in tuberculosis（TB） patients through meta-analysis. Methods Retrieve relevant literature published since the establishment of the database until January 2024 from China National Knowledge Infrastructure（CNKI） Database,Wanfang Database,China Science and Technology Journal Database,Pubmed,Cochrane Library,and Embase Database. Two researchers selected appropriate studies according to the established inclusion and exclusion criteria. Meta-analysis was performed with R 4.3 and Stata 14.0 software, and fixed-effects model was used to estimate the overall odds ratio（OR） and its 95%CI. The Newcastle-Ottawa Scale（NOS） was used to assess the quality of the included literature,and meta-analysis results were presented in forest plots,drapery plot,sensitivity analysis,and subgroup analysis. Publication bias was corrected by Egger's linear regression,Begg's rank correlation test,and contour-enhanced funnel plots. Results A total of 528 articles were retrieved,among which 11 literatures met the inclusion criteria. All of the studies were conducted in high TB burden countries. The number of eligible samples obtained was 3 575 for sputum induction and 3 407 for self-expectoration,and the success rate of sputum induction ranged from 78.90% to 100.00%. Meta-analysis results showed that the positive detection rate of Mycobacterium tuberculosis in pulmonary tuberculosis patients detected by sputum induction technique was 1.87 times higher than that of self-expectoration technique（95%CI：1.66-2.09,P<0.01）,and there was no heterogeneity among included studies（I²=0,P>0.05）. Subgroup analysis by clinical diagnostic classification,sample testing method,pretreatment of sputum,saline concentration,and induction duration showed consistent results with the overall results. Egger's linear regression（t=2.767,P<0.05） and Begg's rank correlation test（Z=2.352,P<0.05） showed publication bias,and the original results were considered reliable after correcting for publication bias through trim and fill method. Conclusion Compared with self-expectoration,the induced sputum technique can improve the positive detection rate of sputum samples from TB patients,and is a safe,convenient and cost-effective method of operation.

Health Management and Research

Prediction and analysis of total health expenses in Inner Mongolia based on ARIMA-GM（1,1） combination model

QUAN Zhiwei, WANG Jiamei, SUN Jing

2025, 41(11):  1552-1557. 

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Objective To predict the total health expenses and their proportion to gross domestic product（GDP） in Inner Mongolia Autonomous Region from 2022 to 2030,and provide scientific and systematic basis for relevant health departments to adjust health policies. Methods Using the total health expenses and related data of Inner Mongolia Autonomous Region,a combination model was established based on ARIMA and GM（1,1） models to analyze and predict the total health expenses and their proportion to GDP in Inner Mongolia Autonomous Region from 2022 to 2030. Results The data fitting effect of the combination model was good,and it was the optimal model. It is expected that by 2030,the total health expenditure will increase to 216.349 billion yuan,and the proportion of total health expenditure to GDP will reach 8.83%. Conclusion The total health expenses and the proportion of total health expenses to GDP in Inner Mongolia will show a stable growth trend in the coming years. During this period,Inner Mongolia needs to control its reasonable growth,ensure that the investment in health expenses is coordinated with the economic development level of the autonomous region,improve the efficiency of health services,provide better and more efficient health services to the people of the autonomous region,and promote the sustainable development of health policies.

Survey on satisfaction with the effectiveness of professional competency training for resident physicians in Tianjin

ZHANG Xiaoling, SONG Jiahui, LIU Hongliang

2025, 41(11):  1558-1562. 

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Objective To understand the satisfaction level of professional competence training for standardized training of resident physicians in Tianjin,and to provide reference for improving residential training work in the future. Methods A self-designed questionnaire was used to conduct a satisfaction survey among 329 resident physicians enrolled in Tianjin's 2022 training program using stratified random sampling by grade from February 20 to 28,2023. Principal component analysis was used to calculate the weights of each dimension indicator. Results In the comprehensive evaluation of resident physicians' satisfaction with professional competency,the weights of influencing factors from highest to lowest were training effectiveness（21.26%）,assessment and management （20.80%）,training base conditions（20.50%）,teaching quality（20.41%） and salary benefits（17.03%）. There were statistically significant differences in the satisfaction of resident physicians with different educational backgrounds,training grades,marital and pregnancy status,and types of trainee（all P<0.05）. Conclusion The overall satisfaction with the standardized training for resident physicians in Tianjin is good. The four dimensions of training effectiveness,assessment and management,training base conditions,and teaching quality have a significant impact on the satisfaction of resident physician training.

Overview

Research progress on genotoxicity and mechanism of carbon black particles

CHENG Xuan, YAO Yan, WANG Kun, ZHANG Siyu, ZHANG Zhidong, MENG Tao

2025, 41(11):  1563-1568. 

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Carbon black（CB） is a stable nano-scale industrial material,which has been widely used in rubber,tires,plastics,batteries,printing and other industries. Due to the small size of CB particles,they can enter the cell and cause damage to genetic material through direct or indirect effects. At present,the International Agency for Research on Cancer classifies CB as a suspected human carcinogen. Most in vitro and in vivo studies have confirmed the genotoxicity of CB. In animal studies,only rats have been tested positive for the carcinogenicity of CB,while the population epidemiological carcinogenic evidence and the studies of genetic damage mechanism of CB are relatively limited. Based on the toxicological data of CB,this paper systematically reviews the characteristics,toxicokinetics,occupational exposure,genotoxicity assessment,genotoxic mechanism and carcinogenic effects of CB,so as to provide scientific basis for the health risk assessment and the formulation of prevention and control measures of CB particles.

Research progress on management and disposal of radioactive waste in nuclear technology application

ZHANG Xinrui, MA Xiufeng, DU Juan

2025, 41(11):  1569-1573. 

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With the rapid development of nuclear technology application in China,the amount of radioactive waste generated is also increasing. If not managed properly,it will bring harm to society. Based on the research progress of radioactive waste management and disposal internationally,combined with the research progress and current situation of management and disposal of radioactive waste in China's nuclear technology application,this paper proposes the focus points of improving management and disposal of radioactive waste in China's nuclear technology application,which can provide scientific basis to assist government in decision-making and promote sustainable development of nuclear technology application.

Research progress of just-in-time adaptive interventions in community chronic disease health management

WANG Xiaotong, HU Pei, WANG Yuncui, ZHOU Shi, LI Yucan

2025, 41(11):  1574-1579. 

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With the continuous development of artificial intelligence technology,exploring new strategies for chronic disease health management has become a general trend. Previous research perspective of intelligent healthcare in chronic disease health management was mostly static assessment and intervention,lacking research on dynamic adaptability. Moreover,China's current research on dynamic intervention programmes is still in the construction stage. In view of this,this paper will start from the definition and characteristics of just-in-time adaptive interventions,comprehensively summarize the research progress of just-in-time adaptive interventions in chronic disease health management,and then analyze the development dilemma and countermeasures of just-in-time adaptive interventions,so as to provide reference for its clinical application in chronic disease patients in China.

Research progress on psychological support for polar operators

WANG Lichao, OUYANG Yifan, LIANG Chenhua, YU Hao, ZHENG Wenwen, FENG Yifei

2025, 41(11):  1580-1584. 

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The exploration and development of polar regions is an important part of our country's strategy for building a maritime power. As the main implementers,personnel engaged in polar operations play a crucial role. However,the unique natural and social environments of polar regions can significantly impact the psychological state of these workers,which in turn affects their work efficiency. Therefore,it is essential to pay attention to the mental health of operational personnel. This article reviews the psychological characteristics of operators in polar environments and the mechanisms affecting their psychological performance,and subsequently proposes coping strategies to provide a theoretical foundation for the in-depth implementation of psychological support in polar regions,in order to play a positive role in improving the quality and efficiency of scientific research missions.