OCCUPATION AND HEALTH

Analysis of thyroid nodule detection rate and influencing factors among employees in a large electrical appliance manufacturing company in Wuhu City

LI Lei, WU Yan, WANG Jiangbo, ZHAO Wanjun, ZHANG Xiancui, CHEN Jianping

2025, 41(6): 721-725.

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Objective To understand the current status of thyroid nodules among employees in a large electrical manufacturing company in Wuhu City,and analyze its risk factors,so as to provide a certain basis for the prevention of thyroid nodules. Methods A total of 4 159 employees aged 18 to 85 from a large electrical manufacturing company in Wuhu City who underwent occupational health examinations at the health management center of the First Affiliated Hospital of Wannan Medical College from January to July 2022 were selected as the research subjects. Determine whether employees had thyroid nodules through color Doppler ultrasonography,and divide them into non-thyroid nodules group（n=1 546） and thyroid nodules group（n=2 613）. The detection and characteristics of thyroid nodules in different age groups were analyzed. Multivariate logistic regression analysis was used to determine independent risk factors for thyroid nodules in different age groups. Results The total detection rate of 4 159 subjects was 62.83%,including 700 cases of male thyroid nodules with a detection rate of 49.16%,and 1 913 cases of female thyroid nodules,with a detection rate of 69.95%. There was a statistically significant difference in the detection rate of thyroid nodules among employees of different genders（P<0.01）. There was a statistically significant difference in the detection rate of thyroid nodules among different age groups,and the detection rate of thyroid nodules increased with age（χ²=171.102,P<0.01）. Multivariate logistic regression analysis showed that gender,age,surgical history,aspartate/alanine aminotransferase,thyrotropin,free tetraiodothyronine,and thyrotropin abnormalities were independent risk factors for thyroid nodules in electrical appliance manufacturing employees in southern Anhui region. Conclusion The occurrence of thyroid nodules in electrical appliance manufacturing industry in southern Anhui region is closely related to age,suggesting that employees and managers in the electrical appliance manufacturing industry in this area should pay attention to the screening of thyroid nodules in different ages groups.

Current status and correlation analysis of psychological resilience,self-efficacy and practice environment of gastroenterology nurses

ZHANG Hua, WANG Meixia

2025, 41(6): 726-730.

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Objective To investigate the psychological resilience,self-efficacy and practice environment of gastroenterology nurses and analyze their correlations. Methods From December 2022 to January 2024,197 nurses in the gastroenterology department from 5 grade-A tertiary general hospitals in Xi'an were selected as the research objects.General information questionnaire,psychological resilience, general self-efficacy scale（GSES） and practice environment scale（PES） were used to investigate,and the data were analyzed. Results The total score of psychological resilience,PES and GSES for gastroenterology nurses were （56.39±19.75）,（83.91±16.87） and （24.99±9.94）points,respectively.There were statistically significant differences in the self-ability of nurses of different ages,years of work experience,professional titles,employment methods,and monthly incomes（all P<0.05）.There was a positive correlation between the psychological resilience and self-efficacy scale of gastroenterology nurses and the practice environment scale（all P<0.05）. Psychological resilience and self-efficacy as mediating variables,both of which had an indirect impact on the practice environment. Conclusion There is a correlation between the psychological resilience,self-efficacy,and practice environment of gastroenterology nurses. Improving the practice environment of gastroenterology nurses in five grade-A tertiary comprehensive hospitals in Xi'an can enhance their self-efficacy and promote their psychological resilience.

Application research of different occupational health risk assessment methods in buried sewage treatment plants

FAN Xiaomeng, FENG Yuchao, ZHANG Hai, SU Yiwei, WANG Zhi, LIN Jingshu

2025, 41(6): 731-735.

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Objective Taking six buried sewage treatment plants as research objects,the International Council on Mining and Metals（ICMM）,composite index method,and Australian method were used to evaluate occupational health risks,and the evaluation results and applicability of the three methods were compared. Methods In 2022,six buried sewage treatment plants in Guangzhou were selected as evaluation sites,and the ICMM method,comprehensive index method,and Australian method were used to evaluate occupational health risks. The risk levels of the evaluation results were converted into risk ratios for comparison. Results The detection results of exposure to hydrogen sulfide,ammonia,chlorine gas,other dust,and silica dust in all positions of 6 buried sewage treatment plants met the national occupational exposure limit requirements. The evaluation results of the ICMM quantitative method showed that the occupational health risks of hydrogen sulfide,ammonia,and chlorine gas were tolerable risks,other dust were high risk,and silica dust was very high risk. The evaluation results of the ICMM matrix method showed that the occupational health risks of hydrogen sulfide,ammonia,chlorine gas,and other dust were very low,while silicon dust was low risk. The evaluation results of the comprehensive index method showed that the occupational health risks of hydrogen sulfide,ammonia,and chlorine gas were low risks,other dust was negligible risks,and silica dust was moderate risks. The evaluation results of Australian method showed that the occupational health risks of hydrogen sulfide,ammonia,chlorine gas,and silica dust were high,while other dust was significant. The consistency of the evaluation results obtained by the ICMM matrix method and the comprehensive index method was good（P>0.01）,while the consistency of the evaluation results obtained by other risk assessment methods was poor（P<0.01）. Conclusion There are significant differences in the risk assessment results of three evaluation methods applied to buried sewage treatment plants,and the comprehensive index method is more suitable for occupational health risk assessment in buried sewage treatment plants.

Impact of OUR-XGD gamma knife on environmental radiation levels and personal radiation dose assessment of staff in a hospital in Urumqi City

LI Wenzhe, XU Li, XIA Hongjuan, LIU Chenchen, HUANG Yiwei, YUAN Fang

2025, 41(6): 736-740.

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Objective To explore the radiation levels of the main environmental concerns around the head Gamma Knife device and evaluate the personal doses of medical personnel working in this environment. Methods The ionization chamber dosimeter was used to detect focal dose rate of gamma knife from November 2011 to April 2021. At the same time,the SW88 X-γ radiation dosimeter was used to monitor the radiation levels of different environmental focus points inside and outside the OUR-XGD head gamma knife treatment room. Based on dose equivalent rate of the standing position where the medical staff stood close to the treatment bed for assisted treatment and a certain number of patients,personal dose of the staff member can be obtained by approximate calculation. Results Focal dose rate of gamma knife decayed exponentially.The radiation level monitoring of the surrounding environment concerns of the gamma knife showed that during the staff-assisted positioning treatment the average dose equivalent rate in the standing position decreased from 5.10 μSv/h to 1.145 μSv/h. Furthermore,the dose equivalent rate at the edge of the Gamma Knife machine room had been reduced to near background radiation levels. Based on the average annual treatment of 200 people and mean retention time of 10 minutes for each patient,total personal dose was approximately calculated with the value of 0.094 mSv,which met the standards for ionizing radiation protection and radiation source safety. Conclusion Under normal treatment conditions,the personal dose level of operating staff from OUR-XGD gamma knife during the process of assisting patient positioning meets the safety requirements of national standards. Moreover,it has no obvious effect on the radiation level of indoor and outdoor environment under the condition of good shielding.

Investigation on the current situation of highly toxic and highly dusty hazardous enterprises in the Shanghai chemical industrial park

WU Yushan, LIU Pengwei, PENG Xiaoli

2025, 41(6): 741-745.

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Objective To understand the current situation of occupational hazards in high-toxicity and high-dust enterprises in Shanghai Chemical Industry Zone,further strengthen the prevention and control of occupational hazards caused by dust and toxins in the chemical industry zone,control and eliminate occupational hazards,and provide data support for occupational health management in the chemical industry zone. Methods From July 2022 to January 2023,a special investigation on occupational hazards of dust toxicity was organized in the Shanghai Chemical Industry Zone. The "Employer Dust,Toxic Occupational Disease Hazard Self-Inspection Form" was used to distribute and collect dust and toxic enterprises in the chemical industry zone. High toxicity and high dust enterprises in the chemical industry zone were selected for dust toxicity hazards status investigation,occupational hazard factor monitoring was carried out based on the production situation of the enterprises,and the data were summarized and statistically analyzed. Results In Shanghai Chemical Industry Zone,there were 29 enterprises with high toxicity and high dust,with medium-sized enterprises（41.38%） and chemical raw materials and chemical products manufacturing industry （79.31%） accounting for the highest proportion. Enterprises in the chemical industry zone were better in occupational disease hazard project declaration,regular occupational disease hazard factor detection and occupational health examinations. However,there were deficiencies in the training of the main person in charge and occupational health management personnel,the rationality of protective measures,and the effectiveness of facilities against dust and poison,mainly concentrated in small and medium-sized enterprises and the manufacturing industry of chemical raw materials and chemical products. The test results of occupational hazard factors showed that the qualification rate of the total point detection of occupational hazard factors was 96.35%,with formaldehyde and dust exceeding the standard.There were 5 enterprises（17.24%） that exceeded the standard,mainly small and medium-sized enterprises and chemical raw materials and chemical products manufacturing. Conclusion By carrying out the investigation on the management of occupational health and protection facilities in high-toxicity and high-dust enterprises,the current situation of occupational health management in high-toxicity and high-dust enterprises in the chemical industry zone has been basically grasped. It is suggested to strengthen the guidance on occupational health technology for small and medium-sized enterprises,attach importance to high toxicity job positions,formulate targeted governance plans,promote the transformation of protective facilities in enterprises,improve the effectiveness of dust and toxic prevention facilities,continuously improve the working environment of workers,and increase the training of occupational disease prevention and control knowledge for main responsible persons and occupational health management personnel,as well as the training of protective skills for on-site operators. Full process supervision should be carried out,and the main responsibility of enterprises should be strictly implemented to ensure the physical and mental health of workers.

Observation of the therapeutic effect of homeopathic and countercurrent administration of β-nicotinamide mononucleotide and taurine on experimental silicosis in rats

GAN Yongjin, CHEN Ruize, LING Jianan, LIANG Danyu

2025, 41(6): 746-749.

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Objective To explore the therapeutic effects of homeopathic and countercurrent administration of β-nicotinamide mononucleotide（NMN） and taurine on experimental silicosis rats. Methods Totally 72 SD specific pathogens free rats,half male and female,sorted by gender and body weight,were randomly divided into a negative control group（not contaminated with dust）,a positive control group,a countercurrent administration group,and a homeopathic administration group using computer randomization,with 18 rats in each group.A rat silicosis model was established by injecting 50 mg/rat of free silica dust into the lungs. On the fourth day after administered,rats in the countercurrent administration group were given NMN solution by gavage in the morning and taurine solution by gavage in the afternoon,the administration sequence of rats in the homeopathic administration group was opposite to that in the countercurrent administration group.And the negative control group and positive control group were given equal amounts of ultrapure water by gavage in the morning and evening. All four groups of rats were administered 5 days a week for a total of 6 weeks. Rats were euthanized 6 weeks after administration,and lung hydroxyproline content,whole lung free silica content,cell count and classification in lung lavage fluid,whole lung dry wet weight,organ coefficient,and pathological changes in lung tissue were detected. Results The lung hydroxyproline content,lung organ coefficient,whole lung wet weight,whole lung dry weight,total cell count,neutrophil rate,and whole lung free silica content in the homeopathic administration group and countertrend administration group were 0.311 mg,0.321 mg,0.622%,0.675%,1.963 g,2.101 g,0.383 g,0.411 g,17.208×10⁹ cells/L,19.375×10⁹ cells/L,57.333%,54.500%,5.650%,and 6.562%,respectively,which were significantly lower than those in the positive control group,and the differences were statistically significant（all P<0.05）.In the positive control group,round or oval nodules were formed in the lung tissue,which were phagocytic cellular nodules,and the alveolar structures in some areas still existed.The experimental group by homeopathic administration and countercurrent administration were similar to those of the positive group,but the degree was relatively mild. Conclusion NMN and taurine have a certain improvement effect and dust removal effect on experimental silicosis rats by homeopathic and countercurrent administration.

Determination of 8 fluorescent whitening agents in flour by ultra performance liquid chromatography-tandem mass spectrometry

XIE Jiangning, XU Haitang, QIN Kunfei, ZENG Yongfang

2025, 41(6): 750-755.

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Objective To establish an analytical method for simultaneous determination of eight fluorescent whitening agents （FWAs） in flour using ultra performance liquid chromatography-tandem mass spectrometry. Method The target compound in flour samples were extracted with acetonitrile by vortex ultrasound method. 2 mmol/L ammonium acetate（plus 0.1% formic acid） buffer and acetonitrile were used as mobile phase for gradient elution,and the target compounds were separated by Phenomenex Kinetex C₁₈（100 mm×2.1 mm,2.6 μm）.The multiple response monitoring（MRM） was selected in the positive electrospray ionization mode to quantitatively analyze eight FWAs,and the target compounds were quantified by matrix-matched external standard method. Results A good linear relationship among 8 FWAs in the range of 0.10-100 μg/L,with a correlation coefficient（r） ≥0.99. The detection limit and quantitation limit of FWA184 were 0.01 and 0.05 μg/kg.The detection limit and quantitation limit of FWA162,FWA185 and FWA367 were 0.03 and 0.10 μg/kg.The detection limit and quantitation limit of FWA140,FWA199,FWA378 and FWA393 were 0.05 and 0.20 μg/kg.The average recoveries of the method were in the range of 82.4%-113.7%,and the relative standard deviations ranged from 1.1% to 6.2% at three spiked levels. Conclusion The established method is simple,fast,accurate and covers a wide range of FWAs,making it suitable for the determination of 8 types of FWAs in flour.

Rapid screening of a poisoning incident caused by tripterygium wilfordii

KOU Jinchan, SUN Mingyue, ZHOU Ronggui, LIN Ji

2025, 41(6): 756-762.

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Objective To rapidly screen a food poisoning incident,using ultra-performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry（UPLC-Q-TOF-MS） technology,laying an experimental foundation for the subsequent identification of tripterygium wilfordii toxin. Methods The ultrasonic-assisted methanol extraction method was used to extract toxins from tripterygium wilfordii plants in a poisoning incident that occurred in a city in Yunnan Province in May 2023. In the experiment,an ACQUITY UPLC^® BEH C₁₈ chromatographic column（2.1 mm×50 mm,1.7 μm） was selected to achieve effective separation of each component,and the column temperature was set at 40 ℃. A gradient elution method was applied with 0.1% aqueous formic acid as the aqueous phase and methanol as the organic phase,maintaining a flow rate of 0.3 mL/min and an injection volume of 2.0 μL. Results The linear correlation coefficients（r） of the nine target compounds were all >0.999 within the concentration range of 5.0-500 ng/mL,indicating a good linear relationship among the substances. At the same time,the relative standard deviation（RSD） of the intra-day precision was ≤3.9%,the RSD of inter-day stability was ≤6.9%,and the spiked recoveries rate was 99%-111%,demonstrating high precision and stability. Collect one remaining branch and leaf in the patient's home and one fresh branch and one dead branch in the field identified by the patient. Morphological identification showed that it was tripterygium wilfordii,and rapid screening of botanical specimens using UPLC-Q-TOF-MS detected triptolide in all samples. Conclusion This poisoning incident stems from the unintentional consumption of tripterygium wilfordii foliage,resulting in a foodborne poisoning case. The detection method is easy to operate,highly sensitive,precision,and efficient.

Study on the different effects of quercetin on normal oral cell lines and cancer cell lines and their antioxidant mechanisms

ZHOU Xiao

2025, 41(6): 763-767.

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Objective To observe the effects of quercetin on the proliferation,migration,and damage of normal human oral epithelial cells and oral cancer cells ,and explore its mechanism. Methods DOK and HSC-4 cell lines were cultured in vitro,and two types of cells both were divided into a control group and a quercetin（50 μmol/L） treated group.HSC-4 cell line added quercetin（50 μmol/L） group and H₂O₂（10 μmol/L） group. The response of DOK and HSC-4 cell lines to quercetin intervention was observed,lactate dehydrogenase（LDH） content of each group's culture medium was detected by colorimetric method,colony formation rate of each group was detected by plate colony formation assay,cell migration ability of each group was detected by cell invasion assay,and cell mortality rate of each group was detected by Annexin-V-FITC-PI dual staining flow cytometry. To explore the possible mechanism of quercetin's anti oral cancer effect,intracellular reactive oxygen species（ROS） levels in DOK and HSC-4 groups was detected by colorimetric method. Results There were no statistically significant differences in various detection indicators between the quercetin treated group and the control group of normal oral epithelial cells DOK（all P>0.05）. There were statistically significant differences in the degree of damage,mortality rate,colony formation rate（%）,invasion ability,and intracellular ROS levels between the HSC-4 oral cancer cells of quercetin treated group,quercetin+H₂O₂ group,and control group（all P<0.05）. Conclusion Quercetin intervention has no significant effect on the proliferation,migration,and apoptosis of normal human oral epithelial cells DOK,but it has inhibitory effects on proliferation and migration,promotes damage,and increases mortality in human oral cancer cell line HSC-4. Its mechanism of action may be related to the reduction of ROS levels in HSC-4 cells by quercetin.

Study on the acute toxicity and genotoxicity of 1-ethynylcyclohexanol

WANG Weina, HONG Lihua, YANG Weichao, LI Ruiqian, ZHANG Jungang, LI Xingqin

2025, 41(6): 768-772.

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Objective To analyze the acute toxicity and genotoxicity of 1-ethynylcyclohexanol,and provide toxicological data for its safety use. Methods The up and down procedure（UDP） was used to determine the acute oral toxicity of 1-ethynylcyclohexanol. The toxicity of 1-ethynylcyclohexanol to cells in vitro was evaluated by observing the changes in cell morphology and cell survival rate after exposure. The genotoxicity of 1-ethynylcyclohexanol was detected using mouse bone marrow micronucleus assay,salmonella typhimurium reverse mutation assay（Ames test）,and in vitro chromosomal aberration assay based on double chamber slides. Results The median lethal dose（LD₅₀） of acute oral toxicity of 1-ethynylcyclohexanol in mice was 1 098 mg/kg·bw（95%CI 550-2 000 mg/kg·bw）.As the dose of 1-ethynylcyclohexanol increases,it was observed under the microscope that the adherent cell morphology gradually became round until most of the cells were autolysed,and the number of cells gradually decreases. The tetramethylazolyl blue（MTT） assay showed that the semi-inhibitory concentration（IC₅₀） of 1-ethynylcyclohexanol on Chinese hamster lung cells（CHL） were 1 970（+S9,6 h）、1 935（-S9,6 h）和1 835（-S9,24 h）μg/mL.Ames test results indicated that under ± S9 conditions,each dose group had no mutagenic effect on the four test strains（TA979a、TA98、TA100、TA102）. The average rates of micronucleus containing cells in male and female mice in the three dose groups had no statistically significant difference compared with the negative control group（all P>0.05）. The results of the in vitro chromosome aberration test showed that under the three treatment methods of ±S9（6 h） and -S9（24 h）,there were no statistical significance in chromosome aberration rates of each dose compared with negative control group（all P>0.05）. Conclusion Under the conditions of this experiment,the acute oral toxicity of 1-ethynylcyclohexanol is classified as low toxicity. It exhibits cytotoxicity at concentrations of 500-2 500 μg/mL and is positively correlated with dose,but no genotoxicity was observed.

Analysis of dietary quality and influencing factors among school age children in Suzhou City

DING Lei, WANG Bo, ZHENG Yanmin

2025, 41(6): 773-777.

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Objective To understand the dietary quality of school-aged children in Suzhou City and analyze the influencing factors,so as to provide reference for improving the dietary quality of school-aged children. Methods Based on the residents food consumption and health survey database in Suzhou from 2018 to 2020,school-age children aged 6 to 17 with complete dietary data were selected as the survey subjects.The dietary guideline index（2021） was used to evaluate dietary quality,and multiple linear regression model was used to analyze the influencing factors of dietary quality. Results A total of 506 school-age children were included,with a sex ratio of 1.32∶1,an age M（P₂₅,P₇₅） of 14.00（12.00,16.00）years,and a dietary guideline index（2021） score[M（P₂₅,P₇₅）] of 74.63（66.73,83.56）points,the diet index scores for vegetables,fruits,other grains and beans,snacks,livestock and poultry meat,nuts,and aquatic products were relatively low. Age（11-<14 years old,β=3.821,t=3.209）,father's education level（high school and college,β=4.184,t=2.923;bachelor's degree or above,β=5.609,t=3.092）,non-smoking parents,（β=3.235,t=3.060） and screen time（<2 h/d,β=3.115,t=2.978） were all the influential factors of dietary index score of school-age children aged 6-<18 in Suzhou City（P<0.01）. Conclusion The dietary guidelines index（2021） score for school-age children in Suzhou City[M（P₂₅,P₇₅）] is relatively high,but the dietary structure was not reasonable enough. The dietary quality of school-aged children in Suzhou may be affected by age,father's education level,parents' smoking and screen time.

Correlation analysis of workplace bullying,psychological resilience,and mental health among emergency department medical staff in tertiary hospitals

JIN Xingcao, WANG Ying

2025, 41(6): 778-784.

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Objective To investigate the current situation and correlation of workplace bullying,psychological resilience and mental health among medical staff in emergency department of tertiary hospitals,analyze the influence of workplace bullying and psychological resilience on mental health,and provide suggestions for improving the mental health status of medical staff. Methods From January to February 2024,a convenience sampling method was used to select medical staff in emergency departments of six tertiary hospitals in Mianyang City as the survey subjects. A cross-sectional survey was conducted on 268 emergency department medical staff using the workplace bullying scale,psychological resilience scale,and mental health scale,and the data were analyzed. Results The workplace bullying score of 268 emergency medical staff was （57.78±16.30）points,the score of psychological resilience was （76.25±13.65）points,and the score of mental health was （30.94±7.02）points. Univariate analysis showed that there were statistically significant differences in mental health scores of emergency medical staff with different genders,marital status,educational background,job category,length of service in the emergency department,average weekly overtime hours,night shifts,health status,work pressure,sleep quality,and those who received psychological decompression training（all P<0.05）. Correlation analysis showed that the mental health score of medical staff in emergency department was positively correlated with the psychological resilience score（r=0.497-0.772,all P<0.05）,and negatively correlated with workplace bullying（r=-0.492--0.658,all P<0.05）. Marital status,average weekly overtime,health status,work pressure,sleep quality,workplace bullying and resilience were the main influencing factors of mental health of medical staff in emergency department（all P<0.05）,which explained 56.1% of the total variables. Conclusion The mental health status of emergency medical staff in tertiary hospitals is poor,and workplace bullying and resilience are important influencing factors. Managers should pay attention to workplace bullying behavior among medical staff and improve their psychological resilience,so as to improve the mental health status of medical staff.

Study on the nurszs' regulatory focus,professional values and occupational delay of gratification in grade-A tertiary hospitals

MIAO Hui, WANG Peijuan, WANG Jiayu, YU Tianshuang, WANG Shanshan

2025, 41(6): 785-788.

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Objective To investigate the correlation among regulatory focus,professional values and occupational delay of gratification of clinical nurse in grade-A tertiary hospitals,and to provide scientific and effective basis for nursing management. Methods In November 2023,a convenience sampling survey was conducted on 321 nurses from 9 grade-A tertiary hospitals in Tianjin,Beijing,and Hebei Province using a questionnaire star format,including a general information questionnaire,a nurse professional values scale,a nurse regulatory focus scale,and a vocational delay of gratification scale,and the data were analyzed. Results The scores for occupational delay of gratification,regulatory focus,and professional values of 321 nurses were （24.39±3.15）,（49.41±4.43） and （107.66±10.22）points,respectively.The comparison of occupational delay of gratification scores among nurses of different genders and educational backgrounds showed statistically significant differences（both P<0.05）. Gender,education level,promoting regulatory focus,and professional values were all influencing factors of nurses' occupational delay of gratification（all P<0.05）. Conclusion The occupational delay of gratification of 321 nurses is at a moderate level. Enhancing nurses' facilitative regulatory focus and professional values has a significant positive impact on improving their job satisfaction. Nursing managers can enhance the professional satisfaction of nurses and further promote the overall development of the nursing team by strengthening their corresponding abilities.

Analysis of liver function abnormalities and risk factors among chemical and ethylene operation employees in a petrochemical enterprise in Lanzhou

DUAN Huichun, LIANG Gaofeng, WU Jiajia

2025, 41(6): 789-793.

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Objective To understand the liver function abnormalities and risk factors of chemical and ethylene operation employees in a petrochemical enterprise in Lanzhou,and provide theoretical basis for the prevention and treatment of liver function abnormalities. Methods Totally 1 244 chemical and ethylene operation employees from a petrochemical enterprise in Lanzhou were selected as the research subjects,and their health examination information from January to October 2023 at the health management center of Lanzhou Petrochemical General Hospital was collected. Create data on alanine aminotransferase（ALT）,total bilirubin（TBIL）,γ-glutamyl transpeptidase（GGT）,uric acid（UA）,and triglycerides（TG） in an Excel 2018 spreadsheet. Based on the patient's liver function,divide the patients into two groups：normal liver function group and abnormal liver function group. Analyze the data using a logistic regression model. Results Among 1 244 study subjects,249 cases were detected for abnormal liver function,with a detection rate of 20.02%. There were statistically significant differences in the abnormal rates of liver function among employees with different years of exposure,body mass index（BMI）,alcohol consumption,fatty liver,hyperlipidemia,hyperuricemia,job type,and age（all P<0.05）. The results of multivariate analysis showed that years of exposure to occupational hazards,BMI,alcohol consumption,fatty liver,hyperlipidemia,hyperuricemia,exposure to ethylene,olefins,and methyl ethyl ketone were independent risk factors for liver dysfunction among chemical and ethylene operation employees in a petrochemical enterprise（OR=1.609,2.807,3.044,1.717,1.258,2.964,1.190,all P<0.05）. Conclusion The abnormal liver function of chemical and ethylene operation employees in a certain petrochemical enterprise in Lanzhou is related to risk factors such as years of exposure to occupational hazards,BMI≥28 kg/m²,alcohol consumption,fatty liver,hyperlipidemia,hyperuricemia,exposure to ethylene,olefins,and methyl ethyl ketone,and occupational health protection measures should be taken for employees.

Chain mediating role of adversity quotient and sense of life meaning in the perceived social support and flourishing among nurses in traditional Chinese medicine hospitals

TANG Haixia, LIU Jingjing, WANG Yueyou, SHE Hui

2025, 41(6): 794-799.

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Objective To explore the chain mediating role of adversity quotient and sense of life meaning in the perceived social support and flourishing among nurses in traditional Chinese medicine hospitals,and to provide reference for improving the level of flourishing among nurses in traditional Chinese medicine hospitals. Methods From July to December 2023,656 nurses from 9 traditional Chinese medicine hospitals in Anhui Province were investigated by using self-made general information questionnaire,perceived social support scale,adversity response profile,China meaning in life questionnaire and the flourishing scale to construct and verify the mediation effect model. Results Nurses in traditional Chinese medicine hospitals scored （63.12±9.12）points in perceived social support,（130.58±18.07）points in adversity quotient,（47.23±6.48）points in sense of meaning in life,and （41.95±8.82）points in flourishing.The total score of flourishing among nurses in traditional Chinese medicine hospitals was positively correlated with perceived social support,adversity quotient and sense of life meaning（all P<0.05）.The indirect effect of perceived social support on flourishing was established,and the total indirect effect was 0.302.The specific mediating effect of adversity quotient accounted for 24.8% of the total indirect effect,and the specific mediating effect of the sense of meaning in life accounted for 61.6% of the total indirect effects. The chain mediating effect of adversity quotient and sense of meaning in life on the perceived social support and flourishing among nurses in traditional Chinese medicine hospitals accounted for 13.6% of the total indirect effect. Conclusion The chain mediating effect between adversity quotient and sense of meaning in life is established in perceived social support and flourishing. Nursing managers in traditional Chinese medicine hospitals should increase their support for nurses,formulate relevant measures to improve their adversity quotient and sense of life meaning,and thereby improve their level of flourishing.

Study on the quality of life and influencing factors among man who have sex with man living with HIV

ZHANG Jiayu, XU Hao, CHEN Weihua, WANG Xuting

2025, 41(6): 800-804.

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Objective To explore the quality of life（QOL） and influencing factors among man who have sex with man living with HIV（MSM-HIV） in Huangpu District of Shanghai. Methods From March to September 2023,MSM-HIV were recruited in Huangpu District of Shanghai for a questionnaire survey.The QOL was assessed by the World Health Organization Quality of Life Questionnaire for HIV brief version（WHOQOL-HIV-BREF）,and the influencing factors of their QOL were analyzed using multiple linear regression. Results Totally 55 MSM-HIV were included,with a total QOL score of（77.01±11.41）points,including physiological domain（11.95±2.21）points,psychological domain（11.65±2.57）points,independence domain（13.47±1.64）points,social relationship domain（12.78±2.63）points,environmental domain（13.32±2.61）points,and mental domain（13.84±3.33）points. Univariate analysis showed that there were statistically significant differences in the QOL of MSM-HIV in different places of residence,education level,marital status,treatment time,self-rated health,and HIV/AIDS related-stigma and discrimination（all P<0.05）. The results of multiple linear regression analysis indicated that self-rated good health was a positive factor affecting QOL,while feeling stigma and discrimination was a negative factor. Conclusion The QOL of MSM-HIV in Huangpu District of Shanghai is affected by many factors. Targeted work should be carried out to eliminate AIDS discrimination and improve the QOL of patients in an all-round way.

Empirical test of the competency model of special operations personnel in our army

ZHAO Houyu, YU Zeyuan, LIANG Kun, ZHANG Xinghui, FANG Yiqun

2025, 41(6): 805-810.

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Objective To empirically test the pre-constructed theoretical competency model of special operations personnel in our army using exploratory and validation factor analysis. Methods Based on the constructed competency model of special operations personnel in our army,a "self-assessment questionnaire of competency characteristics of special operations personnel in our army" was designed. A questionnaire survey was conducted on 680 special operations personnel in July and August 2023,and exploratory factor analysis and confirmatory factor analysis were used to empirically test the above model. Results The results of exploratory factor analysis were consistent with the theoretical competency model. Exploratory factor analysis showed that the structure of competency model of special operations personnel in our army included 38 items in four dimensions：ability,military-related qualities,personality,and attitude,with Cronbach's Alpha coefficients of each dimension ranging from 0.880 to 0.975（all P<0.05）.The results of confirmatory factor analysis showed that the fitness index of the model reached the standard after modification（χ²/df=1.955,RMSEA=0.029,IFI=0.954,TLI=0.934,CFI=0.953）,indicating that the measurement model had good external quality. There were positive correlations between the four latent variables,with correlation coefficients ranging from 0.530 to 0.840（all P<0.05）. Moreover,each potential variable had good reliability and convergent validity（CR=0.891-0.978,AVE=0.541-0.746）,indicating that the internal quality of the measurement model and the potential characteristics of potential variables were nice. Conclusion The competency model of special operations personnel in our army is reasonable and can provide a reference basis for the selection,evaluation and training of special operations personnel in our army.

Analysis of changes in water pH value and its relationship with other water quality parameters in Xinjiang's water supply system from 2020 to 2022

FU Ruonan, WANG Chang, ZHANG Jing, LIN Qin, ZHANG Ling, LI Jie

2025, 41(6): 811-815.

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Objective To understand the trend of pH value changes in water supply system in Xinjiang and its relationship with other water quality parameters. Methods The water quality monitoring data of 87 monitoring units for urban and rural water supply plants in Xinjiang Uygur Autonomous Region from 2020 to 2022 were collected,and the data were analyzed. Results From 2020 to 2022,a total of 18 656 water samples were monitored,with pH values[M（P₂₅,P₇₅）] of 7.78（7.40,8.00） and the total qualified rate of 99.69%. The pH qualification rate showed an increasing trend year by year from 2020 to 2022（χ²=16.045,P<0.01）. There was a statistically significant difference in pH values between urban drinking water and rural drinking water under different sampling types（χ²=14.213,P<0.05）. There was a statistically significant difference in pH values between surface water source drinking water and groundwater source drinking water under different water source types（χ²=116.034,P<0.05）. The total hardness,chroma,and chloride significantly negatively predicted the pH value of water（β=-0.101,-0.192,-0.069,all P<0.01）,while sulfate significantly positively predicted the pH value of water（β=0.106,P<0.01）.Turbidity and chromaticity values were correlated with the probability of predicting the pH value of drinking water to be qualified. Conclusion pH value is associated with some water quality parameters and can reflect water quality situation. In different water source types,the relationship between water pH value and other water quality parameters is different,and it is affected by other physical and chemical parameters.

Research on the correlation between moral sensitivity and empathy ability of intern nursing students

LI Nannan, WANG Jiachi, LI Mengjie, SU Xuan, CHENG Qiuhong

2025, 41(6): 816-820.

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Objective To understand the current situation of moral sensitivity and empathy ability of intern nursing students,and analyze the relationship between them and the influencing factors of intern nursing students' moral sensitivity. Methods A total of 216 intern nursing students were selected from a grade-A tertiary hospital in Henan Province from January to February 2024 by convenience sampling method. General data questionnaire,moral sensitivity scale and Jefferson empathy scale（nursing student version） were used for questionnaire investigation,and the data were analyzed. Results The total score of moral sensitivity of 216 intern nursing students was（49.37±6.40）points,which was at an above average level,and the total score of empathy ability was （106.10±15.37）points. Uni-variate analysis showed that age,gender,educational background,whether receiving medical ethics education or training,and monthly night shift during practice were the influencing factors of moral sensitivity of intern nursing students（all P< 0.05）. Pearson correlation analysis showed that there was a positive correlation between moral sensitivity and empathy ability of intern nursing students（r=0.454,P<0.01）. Multiple linear regression analysis showed that gender,education background,whether receiving medical ethics education or training and empathy ability were independent factors affecting the moral sensitivity of intern nursing students. Conclusion The moral sensitivity of intern nursing students is at a high level,and the higher their empathic ability,the better their moral sensitivity. Nursing educators should focus on cultivating the empathy ability of intern nursing students,so as to enhance their moral sensitivity and promote their career development.

Construction of post competency evaluation index system for nursing graduates in traditional Chinese medicine universities

LI Wei, WANG Xiang, HUANG Haichao, PANG Xiaoli, GAO Qingqing, PEI Li

2025, 41(6): 821-825.

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Objective To construct a post competency evaluation index system for undergraduate nursing students in traditional Chinese medicine universities. Methods Based on the iceberg theory,the evaluation index item pool was preliminarily developed through literature research and semi-structured interview.From April to July 2023,two rounds of Delphi expert consultation and Analytic Hierarchy Process were used to determine the items and weights of the post competency evaluation index system for undergraduate nursing students in traditional Chinese medicine universities. Results The effective response rate of experts in both rounds was 100.0%,the expert authority coefficient was 0.91,and the Kendall harmony coefficient ranged from 0.205 to 0.230（P<0.01）.The final determination consists of 6 primary indicators,14 secondary indicators,and 47 tertiary indicators. Conclusion The evaluation index system of post competence of nursing graduates in traditional Chinese medicine universities is scientific and comprehensive,and has certain practical value.This index system can provide a theoretical basis for the cultivation of professional ability of nursing talents in traditional Chinese medicine universities,and provide objective evaluation basis for selecting traditional Chinese medicine nursing talents and training new nurses in medical institutions,which is conducive to promoting the high-quality development of traditional Chinese medicine nursing industry in China.

Knowledge graph of mental health research on Chinese military at high altitude in the past 30 years-a visual analysis based on CiteSpace

YUAN Zuoqin, ZHANG Wenmo

2025, 41(6): 826-830.

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Objective To quantitatively analyze researchers,research institutions,research hotspots,and development trends in the field of mental health of Chinese military at high altitude using CiteSpace visualization software. Methods Taking the CNKI and Army Medical University Online Library as search source,with the help of CiteSpace,this paper analyzes the authors,institutions and keywords,etc. of 422 articlesin this field. Results The number of publications in this field had gone through three stages of development,the stable stage from 1994 to 2003,the circular growth stage from 2004 to 2015,and the gradual decline stage from 2016 to 2023. In the author cooperation network,there were 512 nodes with a total of 1 483 links,and the cooperation between authors was strong.In the institutional cooperation map and frequency ranking,there was less cooperation between institutions,and the Army Medical University was the strongest force in the field. In the map of research hotspots,the top ten hotspots were plateau,mental health,military,high altitude,sleep quality,soldiers,depression,anxiety,psychological stress,and soldiers at high altitude,with high centralit. In the clustering map and the time zone diagram,it was found that the research hotspots could be clustered into 11 categories,which were roughly divided into two aspects：research object and research content on mental health. The mental health research of Chinese military at high altitude in different periods focused on different aspects. Conclusion In the past 30 years,the total amount of research on the mental health of Chinese military at high altitude is relatively small. There are limited authors in this field for a long time,limited cooperation between institutions,less interdisciplinary exchanges,and insufficient innovation in this field. Future research needs to strengthen cooperation and keep pace with the times.

Research on occupational safety and health issues from the perspective of intercontinental differences based on CiteSpace

GUO Fuming, LI Shanshan, ZHENG Chunshan

2025, 41(6): 831-837.

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Objective To analyze the differentiation of research on occupational health in different geographical areas and to grasp the current status and development trends of global occupational safety and health research. Methods The development trend,content distribution,research hotspots,and future prospects of occupational safety and health field were analyzed in depth with the help of 92 074 related literatures retrieved from Web of Science by CiteSpace 6.2.R2 software. Results The current research on occupational safety and health could be categorized into three phases：germinationstage（annual publication volume <1 000 articles）,development stage（annual publication volume 1 000-<2 000 articles）,and explosion stage（annual publication volume >2 000 articles）,and currently,all continents were still in the explosion phase. All continents were jointly concerned about issues such as "prevalence" "mental health" "impact" "work" and "stress". There were differences in focus across continents,with Asia focusing more on the impact of career management（"management" occurs 425 times） and Europe focusing more on the impact of mental health（"mental health" occurs 1 454 times）. According to the keyword hotspot to derive the intercontinental research trend,in which the European research would tend to public health,Oceania tended to mental,emotional and other aspects of the research. Conclusion There are differences in occupational health research across continents,but they all focus on the impact on mental health. At present,global research on occupational safety and health is in a period of rapid expansion.

Investigation and prospects analysis of the implementation of continuing medical education programs via "cloud live broadcast" in Tianjin Hospital,Tianjin City

WEI Huiyun, YE Mei, YU Jingbo

2025, 41(6): 838-844.

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Objective To investigate the current situation of developing the "cloud live streaming" continuing medical education projects at Tianjin Hospital in Tianjin,and to provide empirical evidence for promoting the development of online continuing medical education. Methods By searching the information management platform for continuing education projects on the Tianjin Continuing Medical Education Network,as well as the online application and information feedback systems for national and Tianjin municipal continuing medical education projects,a retrospective analysis was conducted on the overall overview,disciplinary distribution,trainees,and professional titles of the national,Tianjin municipal,and hospital level continuing medical education live streaming and face-to-face teaching projects at Tianjin Hospital from January 2021 to December 2023,and the data were analyzed. Results From January 2021 to December 2023,the number of projects taught through live broadcast at Tianjin Hospital in Tianjin had been increasing year by year. The cumulative number of learnerson the live broadcast projects platform was 40 366,and the number of face-to-face projects was 7 330. The differences in the proportion of participants in live broadcast projects with different professional titles to the total number of participants in each year were statistically significant（χ²=18.284,44.079,36.139,all P<0.05）. The proportion of participants with intermediate professional title to the total number of participants in live broadcast projects was the highest,and the difference was statistically significant（2021：junior/intermediate χ²=6.490,senior/intermediate χ²=16.764,both P<0.05;2022：junior/intermediate χ²=41.692,senior/intermediate χ²=15.158,both P<0.05;2023：junior/intermediate χ²=31.148,senior/intermediate χ²=17.046,both P<0.05）. The number of subjects taught through live broadcast had been increasing year by year. Conclusion The enthusiasm of medical staff to participate in the "cloud live broadcast" continuing medical education projects has significantly increased,especially for medical staff with intermediate professional title. Online continuing medical education has obvious advantages. The promotion and application of the "cloud live streaming" continuing medical education projects,resolves the conflict between work and study among medical personnel effectively,satisfies the personalized needs of knowledge updates for various professional medical personnel,and greatly reduce the burden on grassroots personnel. Under the new situation of building a digital China,achieving digital empowerment of medical education to support the high-quality development of the healthcare industry.

Research progress on the sense of pay equity in clinical nurses

ZOU Yuting, LIANG Ruichen, ZHANG Hongxia, ZHAO Yue, CHENG Jie, ZHANG Daiying

2025, 41(6): 845-849.

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With the in-depth implementation of the reform of the medical system,the remuneration system and distribution mechanism have gradually become the focus of reform. As the subjective psychology of organizational members,the sense of pay equity is the subjective feeling of nurses about the fairness of what they receive in terms of self-pay,and runs through the salary distribution. Improving clinical nurses' sense of pay equity,can play an important significance in promoting the reform of the hospital remuneration system,stabilising the clinical nurses' workforce,and enhancing the enthusiasm of clinical nursing work. Therefore,this paper reviews the research status,commonly used research tools,and influencing factors of clinical nurses' sense of pay equity,aiming to provide reference for nursing managers to develop improvement plans for clinical nurses' sense of pay equity and promote remuneration system reform.

Research progress of eHealth literacy intervention for the elderly

AN Lu, JIA Zhumin, WANG Mengmeng, LIU Chang, LIU Fangfang

2025, 41(6): 850-853.

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Electronic health literacy refers to the ability to obtain,understand,evaluate health information from electronic resources,and apply it to solve health problems. With the development of the Internet,e-health literacy has become an important skill that the elderly need to master. However,the level of electronic health literacy among the elderly in China is generally not high,and constructing effective intervention plans to enhance their electronic health literacy has become an urgent problem to be solved. This paper reviews the concept connotation,the theoretical basis of intervention,and intervention measures of e-health literacy for the elderly,and puts forward relevant suggestions,in order to provide theoretical reference for future intervention research.

Research progress on rumination in HIV/AIDS patients

LYU Meihong, XIA You, YU Yizhi, ZHOU Zhiwei, ZHOU Yang

2025, 41(6): 854-859.

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Due to the dual characteristics of acquired immune deficiency syndrome（AIDS） with chronic disease and infectious disease,most patients will repeatedly and passively think about the disease in the early stage,also known as rumination. Rumination has been shown to help resolve cognitive problems in HIV infected individuals/AIDS patients and promote the recovery of negative emotions. This article mainly reviews the concept,development,research status,evaluation tools,influencing factors and intervention measures of rumination in HIV infected individuals/AIDS patients. In the absence of relevant research,drawing on knowledge from other fields to provide new ideas for domestic researchers on AIDS,with the aim of providing a reference for psychological care of HIV-infected individuals/AIDS patients.

Research progress of mental health literacy of college students

GU Sainan, ZHU Aiyong, SUN Shanshan, SHEN Lingling, ZHAO Fang

2025, 41(6): 860-864.

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Mental health literacy includes a variety of knowledge,perspectives and skills related to mental health,including knowledge of mental health and mental disorders,as well as attitudes and skills related to the prevention of mental health problems,self-help behavior,self-care and seeking help. In higher education institutions,the mental health awareness of college students is regarded as one of the key qualities they need,which plays a vital role in their personal growth and progress. By enhancing education and services on mental health,college students can improve their mental health level,so as to face various challenges and pressures in life more effectively. However,there are few reviews and analysis on college students' mental health literacy. This paper focuses on the relevant definition of mental health literacy,evaluation tools,research status of mental health literacy of college students,influencing factors,intervention strategies and other aspects,in order to provide ideas for Chinese educators to improve the mental health literacy of college students.

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