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    Analysis of job burnout and influencing factors among nurses in grade-A tertiary hospitals in Hunan Province
    Huilin HU, Guanpeng MU, Duohua CAO, Junjie HU, Linlin WU, Lan XIONG
    OCCUPATION AND HEALTH    2025, 41 (23): 3179-3183.  
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    Objective To investigate the current situation and influencing factors of job burnout among nursing staff in grade-A tertiary hospitals in Hunan Province,and to propose targeted and practical solutions,providing reference for assisting medical institutions to formulate intervention measures and management mechanisms. Methods From September to December 2023,1 752 nursing staff from 20 grade-A tertiary hospitals in Hunan Province were randomly selected as the survey subjects. A general information questionnaire and Maslach burnout inventory(MBI) were used for the questionnaire survey,and the data were analyzed. Results The detection rate of job burnout among 1 752 nurses was 67.58%,and the prevalence rates for mild,moderate,and severe job burnout were 12.44%,20.78%,and 34.36%,respectively. Age,educational level,marital status,quantity of children,monthly income,department,weekly working time,self-rated health,occupational environment were the important factors affecting whether or not nurses had emotional exhaustion(all P<0.05). Form of employment,self-rated health,fringe benefits were the key influencing factors of low sense of personal accomplishment(all P<0.05). Monthly income,self-rated health,fringe benefits,salary return were the essential influencing factors of depersonalization(all P<0.05). Conclusion The detection rate of job burnout among nurses in grade-A tertiary hospitals in Hunan Province is high,especially in the aspect of emotional exhaustion,and self-rated health is the most important influencing factor.

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    Exploring the protective effect of resveratrol on aluminum induced cranial nerve injury in rats based on the NLRP3-NF-κB-MMP-9 pathway
    ZHANG Bo, SHI Yong
    OCCUPATION AND HEALTH    2025, 41 (11): 1469-1476.  
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    Objective To explore the protective effect of resveratrol on aluminum induced cranial nerve injury in rats based on the nod-like receptor family pyrin domain containing 3(NLRP3)- nuclear factor kappa-beta(NF-κB)- metalloproteinase 9(MMP-9) pathway. Methods Totally 40 adult rats were divided into a normal control group,an aluminum exposure group,and resveratrol low-dose and high-dose groups(100 and 200 mg/kg). Rats in the aluminum exposure group and the low-dose and high-dose resveratrol group were exposed to aluminum trichloride to establish a model of cranial nerve function injury. During the exposure period,the rats in the low-dose and high-dose resveratrol groups were given daily resveratrol gavage intervention,while the normal control group and the aluminum exposure group were given an equal volume of normal saline. After the experiment,neurological function indicators,blood-brain barrier leakage level,neuronal apoptosis levels in brain tissue,brain tissue NLRP3,NF-κB,MMP-9 mRNA protein expression levels,tumor necrosis factor-α(TNF-α),interleukin-1 beta(IL-1β),nitric oxide synthase(iNOS) levels. Results Compared with the normal control group,the aluminum exposure group showed an increase in neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,NLRP3,NF-κB,and MMP-9 mRNA protein levels in cranial tissue(0.86 ±0.09 vs 3.58±0.29,0.75± 0.08 vs 4.20±0.22,0.97± 0.06 vs 4.12±0.18, 0.29± 0.05 vs 1.74± 0.19,0.38±0.07 vs 1.86± 0.18,0.34±0.08 vs 1.79±0.20), as well as an increase in levels of inflammatory factors TNF-α, IL-1β, and iNOS in cranial tissue,and a decrease in the number of crossing the original platform position,and the differences were statistically significant(all P<0.05). Compared with the aluminum exposure group,resveratrol low-dose and high-dose groups neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,cranial tissue NLRP3,NF-κB,MMP-9 mRNA protein levels(3.58±0.29 vs 2.68±0.19,1.62±0.13,4.20±0.22 vs 2.55±0.17,1.72±0.17,4.12±0.18 vs 3.14±0.13,2.01±0.10;1.74±0.19 vs 1.04±0.13,0.73±0.10,1.86±0.18 vs 1.53±0.16,1.02±0.10,1.79±0.20 vs 1.27±0.18,0.74±0.11),cranial tissue inflammatory factor TNF-α,IL-1β,and iNOS levels decreased,and the number of crossing the original platform position increased,the differences were statistically significant(all P <0.05). Compared with the resveratrol low-dose group, the resveratrol high-dose group showed a decrease in neurobehavioral scores,swimming distance,escape latency,blood-brain barrier leakage rate,apoptosis index of cranial nerve cells,cranial tissue NLRP3,NF-κB,MMP-9 mRNA protein levels and cranial tissue inflammatory factors TNF-α,IL-1β,iNOS levels,an increase in the number of crossing the original platform position,and the differences were statistically significant(all P<0.05). Conclusion Resveratrol has a significant therapeutic effect on aluminum exposure induced cranial nerve injury in rats,and its mechanism is related to the inhibition of NLRP3,NF-κB,and MMP-9 mRNA protein expression induced by aluminum exposure,thereby inhibiting the activation of the NLRP3-NF-κB-MMP-9 pathway.
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    Analysis of job satisfaction,occupational burnout and turnover intention of rural doctors in Huizhou City
    Weiai ZHANG, Xiuying ZHUO, Qisheng ZHU, Feng LUO, Damei HUANG, Xindan DENG
    OCCUPATION AND HEALTH    2025, 41 (23): 3169-3173.  
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    Objective To investigate the current status of job satisfaction,occupational burnout and turnover intention among rural doctors,analyze differences based on demographic variables and explore the relationship between the three,and propose practical measures and strategies to improve job satisfaction,reduce occupational burnout,and alleviate turnover intention among rural doctors. Methods From February to May 2024,a stratified cluster sampling method was used to select 251 rural doctors from three counties and four districts in Huizhou City as survey subjects. The t-tests and ANOVA were performed for inter-group comparisons,and correlation and multiple linear regression analysis were used for multifactor analysis. Results The overall job satisfaction score of the surveyed rural doctors was(63.77±8.54)points,indicating a moderate level of satisfaction. The overall job burnout score was (43.17±18.69)points,indicating a low level of job burnout. The turnover intention score was (8.10±4.16)points,indicating a moderate level of turnover intention. The comparison of job satisfaction scores and occupational burnout scores among rural doctors with different health conditions showed statistically significant differences(both P<0.05). There was a statistically significant difference in the turnover intention scores of rural doctors with different income levels(P<0.05). The five dimensions of job satisfaction were negatively correlated with the three dimensions of occupational burnout,and negatively correlated with turnover intention(all P<0.05). The three dimensions of job burnout were positively correlated with turnover intention(all P<0.05). Multiple linear regression analysis showed that overall satisfaction,welfare satisfaction,and career development satisfaction predicted occupational burnout(all P<0.05),welfare satisfaction had predictive effects on turnover intention(P<0.05),and depersonalization and low sense of accomplishment within occupational burnout had predictive effects on turnover intention(both P<0.05). Conclusion The rural doctors in Huizhou City have a moderate level of job satisfaction,low occupational burnout,and a moderate level of turnover intention. The job satisfaction is negatively correlated with occupational burnout and turnover intention,while occupational burnout is positively correlated with turnover intention. Overall satisfaction,welfare satisfaction,and career development satisfaction are the main dimensions affecting occupational burnout. Welfare satisfaction,depersonalization,and low sense of accomplishment are important dimensions affecting turnover intention.

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    Analysis on monitoring results of occupational hazards in the workplaces of key industries in Hainan Province from 2019 to 2023
    Lingyun QUE, Bin LI, Lei JIN, Yushen CHEN
    OCCUPATION AND HEALTH    2025, 41 (23): 3174-3178.  
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    Objective To monitor the current status of occupational disease hazards in the workplaces of key industries in Hainan Province from 2019 to 2023,and provides a scientific basis for the formulation of prevention and control policies for occupational disease in Hainan Province. Methods The monitoring data on workplace occupational hazards in key industries in Hainan Province from 2019 to 2023 were collected,the trend chi-square test was used to analyze the trend of their occupational disease hazards monitoring,enterprise occupational hygiene training status,workers' occupational health examinations,personal protective equipment and enterprise occupational disease hazards testing. Results A total of 1 088 enterprises were monitored from 2019 to 2023,of which the scale of enterprises was mainly small and micro,accounting for 53.95% and 41.18%,respectively. The over-standard rate of occupational hazards monitoring in enterprises was 54.32%,and the exposure rate of occupational hazards was 36.99%. The over-standard rate in different years showed an increasing trend year by year,while the exposure rate showed a decreasing trend year by year(both P<0.05). The training rates of enterprise leaders,occupational health managers and workers receiving occupational health-related training were 74.45%,73.07% and 77.87%,respectively,and the training rates showed an increasing trend year by year(all P<0.05). The abnormal rates of noise,dust and chemical factors in occupational health examinations were 2.52%,2.42% and 0.40%,respectively. The abnormal rates of various health examinations showed an increasing trend(all P<0.05). The distribution rates of dust masks,noise-proof earplugs or earmuffs and gas masks or masks in enterprises were 84.72%,76.38% and 47.34%,respectively,and the distribution rates showed an increasing trend year by year(all P<0.05). The setting rates of dust-proof facilities,gas-proof facilities and noise-proof facilities in enterprises were 89.68%,51.60% and 71.51%,respectively,and the setting rates showed an increasing trend year by year(all P<0.05). The dust monitoring over-standard rate in key industries workplaces and posts/types of work and the noise monitoring over-standard rate in posts/types of work had been decreasing year by year(all P<0.05). Conclusion The exposure rate of dust and noise in key industries workplaces and the abnormal rate of occupational health examinations in Hainan Province are relatively high,and the hazards of chemical factors in the workplace cannot be ignored. Strengthening occupational health training and regular monitoring of occupational disease hazards in enterprises throughout the province can reduce the risk of occupational diseases.

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    Meta-analysis of the current situation and influencing factors of psychological detachment among nurses in China
    Yizhan CHE, Murong YE, Zhongci ZHONG, Xiaomei GUO, Chao ZHAI, Lijuan DONG
    OCCUPATION AND HEALTH    2025, 41 (23): 3283-3289.  
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    Objective To conduct a meta-analysis on the current status of psychological detachment and its influencing factors among nurses in China. Methods Relevant studies on the influencing factors of psychological detachment among nurses in China were searched in China National Knowledge Infrastructure,VIP Database,Wanfang Database,China Biomedical Literature Service System,PubMed,Embase,Cochrane Library,Web of Science,and other databases. The search period was from the inception of the databases to September 15,2024. Two analysts independently screened the literature,extracted data,and conducted quality assessments. Meta-analysis was performed using Stata 17.0 and RevMan 5.4 software. Results A total of 30 articles were included,involving 11 436 nurses,and 17 influencing factors of psychological detachment were ultimately extracted. The meta-analysis results showed that the psychological detachment score of Chinese nurses was 10.13(95%CI:9.30-10.97)points,and marital status,age,education level,weekly overtime hours,work shift system,years of work experience,professional burnout,work engagement,recovery experience,professional grief,job flourishing,sleep disorders,work-family conflict,relaxation experience,control experience,mastery experience,and workload were the main influencing factors of psychological detachment among nurses(all P<0.05). Conclusion The level of psychological detachment among nurses in China is relatively low,and hospital managers can develop targeted intervention measures based on different influencing factors.

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    Analysis of health related quality of life for occupational population aged 30-<60 in Nanjing City in 2023
    Bin YANG, Qing YE, Tianrui DENG, Yunting XU, Huiqing XU, Fei XU
    OCCUPATION AND HEALTH    2025, 41 (23): 3256-3260.  
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    Objective To investigate the current health related quality of life(HRQoL) status of the occupational population in Nanjing City,and provide some reference for improving the HRQoL of the occupational population. Methods A multi-stage random sampling method was used to randomly select permanent residents aged 30-<60 years in five administrative districts of Nanjing City in 2023 for investigation. The social demographic information,lifestyle and behavior,major chronic disease history,and family history of the survey subjects were collected. The SF-12 scale was used to measure the HRQoL for each participant,and multi factor analysis of variance was introduced to compare the differences in HRQoL between different occupations. Results The average scores of SF-physical component summary(PCS) and SF-mental component summary(MCS) for 22 340 study subjects were (55.94±4.90) and (40.44±4.79)points,respectively. There were statistically significant differences in SF-PCS scores between different age,gender,place of residence,education level,marital status,and body mass status(all P<0.05),while no statistically significant differences in SF-MCS scores between these variables(all P>0.05). The SF-PCS scores for unemployed or domestic workers,industrial workers,business or service industry practitioners,government officials,and technical personnel were (54.02±6.30),(56.36±4.48),(56.33±4.51),(56.03±4.65) and (56.16±4.71)points,respectively,and multivariate analysis of variance showed that there was a statistically significant difference in SF-PCS scores among different occupational categories(F=50.176,P<0.01). Meanwhile,the SF-MCS scores for unemployed or domestic workers,industrial workers,business or service industry practitioners,government officials,and technical personnel were (40.65±5.12),(40.65±4.85),(40.42±4.89),(40.20±4.65) and (40.48±4.56)points,respectively,with statistically significant differences(F=6.738,P<0.01). Conclusion In 2023,the overall HRQoL of the occupational population in Nanjing City is in a moderate to low state,and different occupational groups have different scores.

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    Analysis of noise monitoring results of key industry enterprises in a certain district of Shenzhen from 2022 to 2024
    Yuanjun LIAO, Hao CHEN, Zhiming LI, Jin WANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3190-3194.  
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    Objective To understand the current situation of occupational noise hazards in key industry enterprises in a certain district of Shenzhen,laying a scientific foundation for formulating targeted preventive and control countermeasures. Methods From 2022 to 2024,370 key industry enterprises with noise hazards were selected as the research objects. By collecting basic enterprise information,implementing hygienic surveys,noise operation post detections and evaluations on the production site in accordance with various industry standards,and comprehensively evaluating the use of personal protective equipment according to relevant guidelines. Results From 2022 to 2024,the rate of enterprises with excessive noise was 45.68%,and the rate of excessive noise points was 29.82%. The differences in the rate of excessive noise points among enterprises in different years were statistically significant(χ2=20.101,P<0.01). Large/medium-sized enterprises had the most serious excessive noise situation,and the differences in the rate of enterprises with excessive noise and the rate of excessive noise points among enterprises of different scales were both statistically significant(χ2=20.911,41.190,both P<0.01). The furniture manufacturing industry and the metal manufacturing industry had the highest levels of excessive noise,and the differences in the rate of enterprises with excessive noise and the rate of excessive noise points among enterprises of different industry categories were both statistically significant(χ2=45.253,407.060,both P<0.01). Enterprises from Hong Kong,Macao,and Taiwan had the highest rate of excessive noise and the lowest rate of excessive noise points,and the differences in the rate of excessive noise points among enterprises of different economic types were statistically significant(χ2=11.422,P<0.01). In addition,16.78% of the monitoring points did not have protective facilities installed,and 22.68% of the workers at noise-exposed positions did not receive or wear ear protectors. Conclusion The noise hazards in key industry enterprises in a certain district of Shenzhen cannot be ignored. There are differences in noise over-standard situations and the implementation of protective measures among enterprises of different scales,industry categories and economic types. It is necessary to formulate targeted noise prevention and control strategies and strengthen occupational health management.

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    Analysis on mediating effect of work engagement between organizational identity and professional adaptability among newly-recruited civilian personnel
    Yi LI, Han WANG, Tongmei ZHANG, Fengzhou LIU, Zihui YAO, Xiaocheng WANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3246-3250.  
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    Objective To investigate the current status of professional adaptability among newly-recruited civilian personnel in the military,analyze its relationship with organizational identity,and explore the mediating effect of work engagement between the two,providing a reference for strengthening the modernization of the military. Methods From September to November 2024,a convenient sampling method was used to select 268 civilian personnel participating in initial training for medical positions in a certain military unit as the study subjects. Questionnaires were conducted using the organizational identity scale,work engagement scale and professional adaptability scale,and the data were analyzed. Results The total average score for professional adaptability among the 268 newly-recruited civilian personnel was (5.80±0.76)points,indicating an above-average level. There was a significant positive correlation between organizational identity,work engagement,and professional adaptability among the newly-recruited civilian personnel. Work engagement had a partial mediating effect between organizational identity and professional adaptability,with a mediation effect of 50.05%(P<0.05),accounting for 54.62% of the total effect. Conclusion Military managers should create a favorable organizational environment and improve the level of work engagement among newly-recruited civilian personnel to facilitate their better integration into military life.

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    Trend and spatial distribution of incidence and mortality of pulmonary tuberculosis among population aged ≥10 years old in China
    Qiaomei LI, Cheng JI, Lichao YANG, Jing WU, Caiping GUAN
    OCCUPATION AND HEALTH    2025, 41 (23): 3219-3225.  
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    Objective To investigate the effect of age,period,cohort and geographical space on the incidence and death of pulmonary tuberculosis,and to provide a reference basis for tuberculosis prevention and treatment efforts in China. Methods Age-period-cohort model was used to analyze changes in incidence and mortality of tuberculosis by age,period and cohort,and spatial statistical method was used to explore the spatial clustering of tuberculosis incidence and death. Results From 2005 to 2019,the incidence and mortality of pulmonary tuberculosis in China showed a decreasing trend year by year. The analysis results of age-period-cohort(APC) model showed that the incidence and mortality of pulmonary tuberculosis in Chinese people aged 10 years and older increased with age,and the incidence increased from 54.552/100 000 in the group aged 10-<15 years to 2 688.965/100 000 in the group aged ≥85 years(χ2trend=1495.365,P<0.01),the mortality rate increased from 0.063/100 000 in the 10-<15 year old group to 46.882/100 000 in the ≥85 years group(χ2trend=640.712,P<0.01). Using 2010-2014 as the reference group,the rate ratio(RR) values of incidence and mortality of pulmonary tuberculosis among people aged 10 years and over in China showed a decreasing trend with the advance of time in 2005-2009 and 2015-2019. Using the 1965-1969 cohort as a reference,the RR for pulmonary tuberculosis incidence and mortality was significantly higher in those born before 1965 compared with those born after 1969,with increasing RR for incidence and mortality in those born 1934 and before,peaking in those born 1930-1934. Geographic information system(GIS) analysis results showed spatial clustering of tuberculosis incidence and death in China from 2005 to 2019,with Moran's >0 and Z>1.96,P<0.05. Local autocorrelation results showed that high tuberculosis incidence and mortality were concentrated in Xinjiang Uygur Autonomous Region and Xizang Autonomous Region,and low-low incidence was concentrated in the east and central regions. Conclusion Age-period-cohort is important factors affecting the incidence and mortality of tuberculosis,and there is a spatially clustering in the tuberculosis incidence and death. Therefore,it is necessary to increase screening of the elderly population,conduct tuberculosis knowledge campaigns,and increase the awareness rate of population health knowledge,while increasing economic aids in Xizang Autonomous Region and Xinjiang Uygur Autonomous Region to promote equity and accessibility in health resource allocation and protect population health.

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    Analysis on current status and influencing factors of knowledge,attitude,practice of occupational protection of chemotherapeutic drugs among medical staff
    Ben HU, Yanyun ZHUANG, Jiajing XIAO, Yuanying XIAO, Shengpeng LIU, Zhaoxia ZHANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3236-3240.  
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    Objective To investigate the current status of knowledge,attitude,practice of medical staff on the occupational protection of chemotherapeutic drugs,and analyze its influencing factors,so as to provide reference for the management of occupational protection of clinical chemotherapeutic drugs. Methods Convenience sampling was used to conduct a survey of medical staff in a grade-A tertiary comprehensive hospital in Shenzhen City from November to December 2023,using a general information questionnaire and a clinical chemotherapeutic drugs occupational protection knowledge,attitude,practice questionnaire. Univariate analysis and multiple linear regression were used to analyze the factors influencing the knowledge,attitude,and practice level in chemotherapy drug occupational protection among medical staff. Results A total of 339 medical staff were ultimately included,with a questionnaire response rate of 98.3%. The scores for knowledge,attitude,and practice regarding occupational protection against chemotherapy drugs among medical staff were (29.01±2.68),(12.62±1.52) and (21.07±2.05)points,respectively,with corresponding awareness rates of 80.6%,positive attitude rates of 78.9%,and health-promoting behavior rates of 75.3%. Quarterly training positively influenced the scores for knowledge,attitude,and practice dimensions,while non-oncology departments negatively influenced these dimensions(both P<0.05). Years of work in the pharmacy intravenous admixture service(PIVAS) positively influenced the knowledge dimension score,belonging to the pharmacy department and years of work positively influenced the attitude dimension score,belonging to the pharmacy department positively influenced the practice dimension score,while educational level negatively influenced the practice dimension score(all P<0.05). Conclusion The knowledge,attitude and practice of medical staff in a grade-A tertiary hospital in Shenzhen City on occupational protection against chemotherapy drugs are at a medium level,and need to be improved. We should give full play to the support of departmental resources,carry out effective training and reasonably utilize the method of transferring and assisting to improve the level of occupational protection against chemotherapeutic drugs of medical staff,so as to protect the occupational health of medical staff.

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    Effect of trait anxiety and information overload perception on choice deferral in college students
    Fenge LIN, Lieyu HUANG, Na ZHANG, Jun ZHANG, Luyao TIAN
    OCCUPATION AND HEALTH    2025, 41 (23): 3278-3282.  
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    Objective To explore the influence of trait anxiety on choice deferral and the moderating role of information overload perception. Methods A total of 724 college students from two universities in Guizhou Province from September to December 2023 were selected as the survey subjects by convenience sampling method. General situation questionnaire,trait anxiety scale,information overload perception scale and choice deferral questionnaire were used to investigate,and the data were analyzed. Results The average scores of trait anxiety,information overload perception and choice deferral among 724 college students from two universities in Guizhou Province were (2.13±0.38),(1.51±0.54) and (4.43±1.57)points,respectively. Trait anxiety was positively correlated with choice deferral(r=0.225,P<0.01),information overload perception was positively correlated with choice deferral(r=0.111,P<0.01). Trait anxiety could positively predict individuals' tendency towards choice deferral(β=0.230,P<0.01),and information overload perception negatively moderated the effect of trait anxiety on delay choice(β=-2.996,P<0.01). Conclusion Trait anxiety can affect individuals' tendency to delay choice,and this influence is negatively regulated by information overload perception,that is,individuals with high trait anxiety have a stronger tendency to delay choice if they have a lower perception of information overload.

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    Mediating role of psychological detachment among trauma emergency surgical nurses in the relationship between non-compliant tasks and work-family conflicts
    Xiaosu SHI, Jing MU, Chunxia LIU, Qi ZHANG, Yali ZHAO
    OCCUPATION AND HEALTH    2025, 41 (23): 3241-3245.  
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    Objective To analyze the current situation of non-compliant tasks,psychological detachment and work-family conflict of nurses in trauma emergency surgery department,and to study the mediating role of psychological detachment between non-compliant tasks and work-family conflict. Methods From August to September 2024,a convenience sampling method was used to select 186 nurses from the trauma emergency surgery departments of 10 grade-A tertiary comprehensive hospitals in Hebei Province as the survey subjects. The non-compliant task scale,psychological detachment scale,and work-family conflict scale were used for investigation and analysis. Results The scores of non-compliant tasks,psychological detachment and work-family conflict of nurses in trauma emergency surgery department were (27.39±5.48),(12.43±2.46) and (60.58±12.42)points. The influencing factors of non-compliant task scores of nurses in trauma emergency surgery department included age,professional title,nursing experience,marital status,average monthly income and average monthly number of shifts(all P<0.05). The influencing factors of psychological detachment scores of trauma emergency surgery nurses were gender,age,professional title,nursing experience,marital status,number of children,average monthly income,and average monthly number of shifts(all P<0.05). The influencing factors of work-family conflict scores of trauma emergency surgery nurses were age,professional title,nursing experience,marital status,number of children,average monthly income,and average monthly number of shifts(all P<0.05). There was a positive correlation between non-compliant tasks and work-family conflict among trauma emergency surgery nurses(r=0.604,P<0.01). Psychological detachment of trauma emergency surgical nurses was negatively correlated with work-family conflict and non-compliant tasks(r= -0.584,-0.512,both P<0.01). Psychological detachment of trauma emergency surgery nurses partially mediated the relationship between non-compliant tasks and work-family conflict,with a mediating effect value of 0.250,accounting for 42.81% of the total effect. Conclusion Psychological detachment plays a partial mediating role between non-compliant tasks and work-family conflict in trauma emergency surgery nurses. Reducing the level of non-compliant tasks and increasing the level of psychological detachment can help alleviate the level of work-family conflict in trauma emergency surgery nurses.

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    Concentrations and health risks of mercury in aquatic products from the tributaries of Yongjiang in Guangxi
    Yantao HUANG, Shanfan LIANG, Yunyan FAN, Qiong TANG, Siyi CHEN, Shuting MENG
    OCCUPATION AND HEALTH    2025, 41 (23): 3209-3213.  
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    Objective To understand the content of mercury in common freshwater fish and snails in aquatic products from the tributaries of Yongjiang in Guangxi,and to evaluate the health risks. Methods From August to December 2024,461 samples of 10 species of freshwater fish and snail were collected from two tributaries of the Yongjiang river in Guangxi Zhuang Autonomous Region. The mercury content in the edible parts of aquatic products was determined using the direct mercury analyzer method. The pollution level and health risk were evaluated using the single factor pollution index method and target hazard quotient,and the correlation analysis between mercury content and weight in some fish species was conducted. Results The highest content of mercury among the 11 aquatic products from the Yongjiang in Guangxi Zhuang Autonomous Region was topmouth culter,but the mercury content in all aquatic products did not exceed the standard. The single pollution index showed that 4.4% of silver carps and 100.0% of topmouth culters were mildly polluted by mercury,while the rest of the fish species were at normal background levels. The health risk assessment results indicate that the target hazard quotient for topmouth culters was greater than 1,while the target hazard quotients for the other ten types of aquatic products were less than 1. According to correlation analysis,it was found that there was a significant correlation between the levels of mercury and weight in the dorsal muscles of silver carp and mirror carp. Conclusion All aquatic products sourced from Yongjiang in Guangxi in this collected samples exhibited no instances of mercury exceeding safe limits,with the mercury contamination in the samples remaining at a relatively low level. With the exception of carnivorous fish like the predatory carp,the prolonged consumption of the remaining ten species of aquatic products from Yongjiang in Guangxi poses no significant risk to human health.

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    Analysis on current situation and influencing factors of occupational stability of primary medical staff in Pukou District of Nanjing City
    Zhuqing YU, Peiting CHEN
    OCCUPATION AND HEALTH    2025, 41 (23): 3250-3255.  
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    Objective To investigate the current status of occupational stability among primary medical staff and analyze its influencing factors. Methods A questionnaire survey was conducted among 608 medical personnel from all primary healthcare institutions(7 community health service centers and 57 community health service stations) in Pukou District of Nanjing City from February to March 2022. The occupational stability was measured using a turnover intention scale,and the data were analyzed. Results The occupational stability score of 608 primary medical staff in Pukou District was (2.04±0.06)points. The comparison of occupational stability scores among primary medical staff of different ages,educational backgrounds,years of work experience,average monthly income,and job characteristics showed statistically significant differences(all P<0.05). Age,working hours,career prospects,and hospital culture were factors that affected the occupational stability of primary medical staff(all P<0.05). Conclusion The overall occupational stability of primary medical staff in Pukou District of Nanjing City is relatively good,but there is a low willingness to invest in work. After excluding the effects of general demographic factors,working hours,career prospects,and hospital culture emerged as the key hygiene factors influencing the occupational stability of primary medical staff.

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    Investigation on current situation of occupational happiness among young and middle-aged doctors in grade-A tertiary hospitals in Heilongjiang Province
    Shi QI, Yu WANG, Mei YIN
    OCCUPATION AND HEALTH    2025, 41 (23): 3231-3236.  
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    Objective To investigate the current status of occupational happiness among young and middle-aged doctors in grade-A tertiary hospitals in Heilongjiang Province,and provide reference for improving the level of occupational happiness among young and middle-aged doctors. Methods From March to May 2024,a convenience sampling method was used to select 320 middle-aged and young doctors from grade-A tertiary hospitals in Heilongjiang Province as the research subjects. A general information questionnaire and a medical worker occupational happiness scale were used for the questionnaire survey,and the data were analyzed. Results The occupational happiness score of young and middle-aged doctors in three grade-A tertiary hospitals in Heilongjiang Province was (59.40±8.20)points,with an average score of (2.48±0.34)points for each item. The results of independent sample t-test and analysis of variance showed that there were statistically significant differences in the scores of occupational happiness among middle-aged and young doctors of different ages,number of children,years of employment,professional title,night shift situation,and monthly income(all P<0.05). The number of children(B=-2.798,P<0.01,VIF=1.147),years of employment(B=1.531,P<0.05,VIF=3.713),professional title(B=1.137,P<0.05,VIF=2.606),and monthly income(B=1.713,P<0.05,VIF=2.029) were the influencing factors of their level of occupational happiness. Conclusion The occupational happiness level of young and middle-aged doctors in grade-A tertiary hospitals in Heilongjiang Province is relatively low. Hospital managers should develop plans and strategies to improve their occupational happiness level based on the specific situation of young and middle-aged doctors.

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    Exposure characteristics of formaldehyde and benzene series in hotels in Nanjing and health risk assessment for employees
    Xinwei ZHANG, Lilin XIONG, Yunfei JIA, Qiuyuan ZHU, Ming GE, Yanzhao TANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3272-3277.  
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    Objective To investigate the annual dynamic changes of formaldehyde and benzene series in indoor air of hotels in Nanjing City,and assess the potential health risks for employees,providing data support and reference for the hotel industry to develop more effective hygiene management strategies and measures. Methods During 2021 to 2024,18 hotels will be randomly selected from various districts of Nanjing each year,totaling 72 hotels. A total of 287 air samples were collected to detect the concentrations of formaldehyde,benzene,toluene,and xylene in the hotel air. The Kruskal-Wallis H rank sum test was used to compare the concentrations of four air pollutants in different levels of hotel and different years. Further,according to the health risk assessment model recommended by the US National Environmental Protection Agency and the methods in WS/ T777-2021 "Technical Guidelines for Assessing Environmental Health Risks Posed by Chemical Substances",the carcinogenic risk and non-carcinogenic risk assessment of the four pollutants were carried out in combination with the actual work environment exposure of employees obtained through a questionnaire survey. Results The overall pass rates were 91.30% for formaldehyde,100.0% for benzene,100.0% for toluene,and 100.0% for xylene. In 2021,2023,and 2024,the median mass concentrations of formaldehyde,benzene,and xylene showed a trend of M(express hotels)>M(hotels below three stars)>M(hotels above three stars)(P<0.05). The median mass concentration of formaldehyde showed an overall upward trend from 2021 to 2024,the median mass concentrations of benzene,toluene,and xylene showed an overall downward trend. The carcinogenic risk value of formaldehyde was 6.97×10-6-3.00×10-4,and the carcinogenic risk value of benzene was 4.18×10-7-1.25×10-5. The median non-carcinogenic risk value of formaldehyde was greater than 1,while the non-carcinogenic risk values of benzene,toluene,and xylene were all less than 1. Conclusion From 2021 to 2024,there is a phenomenon of excessive formaldehyde concentration in the air of some hotels in Nanjing. Exposure to formaldehyde and benzene poses different risks to the health of hotel employees. Therefore,further in-depth analysis is needed and attention should be paid to it.

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    Research progress on rehabilitation strategies for pneumoconiosis
    Jia SONG, Jiayi JIANG, Ying ZHOU, Jingqi ZHANG, Lili NING
    OCCUPATION AND HEALTH    2025, 41 (23): 3299-3303.  
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    Pneumoconiosis is one of the serious occupational diseases in China,which is a systemic disease mainly caused by diffuse fibrosis of lung tissue due to long-term inhalation of large amounts of dust. Pneumoconiosis often does not have obvious symptoms and signs in the early stages,but as the condition progresses,the emergence of complications worsens the condition,seriously damaging the physical and mental health of patients and exacerbating their economic burden. The "Chinese Expert Consensus on the Treatment of Pneumoconiosis(2021 Edition)" points out that patients with pneumoconiosis generally face obstacles in terms of exercise ability,physical function,respiratory ability,as well as psychological and social adaptation ability during the continuous treatment process. By adopting appropriate rehabilitation intervention plans and integrating them into the daily life of patients,long-term adherence to implementation will effectively improve the quality of life of patients,enabling them to better return and adapt to society. At present,the main treatment methods for pulmonary rehabilitation in clinical practice include respiratory training,respiratory muscle training,traditional Chinese medicine rehabilitation,psychological intervention,exercise rehabilitation treatment,health education,etc. This article summarizes the research progress of the main rehabilitation strategies for pneumoconiosis and provides suggestions for future development.

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    Relationship between mindfulness,compassion competence and job burnout of nurses in a grade-A tertiary hospital of Linyi City
    LI Jiaoyue, WANG Fengling, YANG Li, ZHANG Xiao, ZHANG Hongqiang, LAN Mengfei
    OCCUPATION AND HEALTH    2025, 41 (12): 1600-1605.  
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    Objective To understand the current status of job burnout of nurses in grade-A tertiary hospital,explore the effects of mindfulness and compassion competence on their job burnout,so as to provide theoretical basis for seeking methods to alleviate nurses' job burnout. Methods From June to October 2023,the nurses in a grade-A tertiary hospital of Linyi City in Shandong Province were investigated by the general information questionnaire,Maslach burnout inventory-human service survey,mindful attention awareness scale,and compassion competence scale for the nurses. The generalized linear model was performed to analyze the factors affecting the job burnout of nurses in grade-A tertiary hospital. Results A total of 513 effective questionnaire were collected. The scores[ MP 25, P 75)] of emotional exhaustion,depersonalization,and personal accomplishment of nurses in grade-A tertiary hospital were 18.00(11.00,25.00),4.00(1.00,7.00) and 12.00(5.00,21.00)points,respectively. The results of generalized linear model analysis showed that the experience of workplace incivility,sense of belonging,mindfulness and compassion competence were the influencing factors of emotional exhaustion score of nurses in grade-A tertiary hospital(all P<0.05),the sense of belonging and compassion competence were the influencing factors of depersonalization score(all P<0.05),and the sense of belonging,mindfulness and compassion competence were the influencing factors of personal accomplishment score(all P<0.05). Conclusion The job burnout of nurses in grade-A tertiary hospital of Linyi City is at a high level,and the nursing managers can reduce nurses' job burnout by creating a civilized working environment and improving nurses' sense of belonging,mindfulness and compassion competence.
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    Analysis of psychological resilience trajectories in newly diagnosed pneumoconiosis patients based on the latent class growth model
    Jiao FAN, Yanwu HUANG, Lijuan CHEN
    OCCUPATION AND HEALTH    2025, 41 (23): 3184-3189.  
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    Objective To deeply analyze the dynamic changes in psychological resilience of newly diagnosed pneumoconiosis patients using the latent class growth model(LCGM),and explore its influencing factors,in order to assist clinical identification of individuals with potential low resilience. Methods A total of 278 newly diagnosed pneumoconiosis patients from a grade-A tertiary hospital in Hunan Province,diagnosed between January and December 2023,were selected as the research subjects. The general information survey questionnaire,the social support rating scale(SSRS),the family care index scale(APGAR), the simplified coping style questionnaire(SCSQ),and the 10-item Connor-Davidson resilience scale(CD-RISC-10) were administered to patients within 24 hours of admission(T0),1 month after diagnosis(T1),3 months after diagnosis(T2),and 6 months after diagnosis(T3). Ordinal multivariate logistic regression analysis was employed to investigate the differences in psychological resilience changes among newly diagnosed pneumoconiosis patients with different demographic characteristics. Results The results of LCGM revealed that the trajectories of psychological resilience changes in newly diagnosed pneumoconiosis patients could be categorized into three types:psychological resilience growth type,psychological resilience stability type,and psychological resilience decline type. Among the 278 newly diagnosed pneumoconiosis patients,68(24.5%) exhibited resilience growth,163(58.6%) exhibited resilience stability,and 47(16.9%) exhibited resilience decline. The results of multiple ordinal logistic regression analysis showed that the differences were statistically significant(all P<0.05). Conclusion The psychological resilience of newly diagnosed pneumoconiosis patients can be categorized into three trajectories:psychological resilience growth type,psychological resilience stability type,and psychological resilience decline type,with the majority of patients falling into the resilience stability category. Healthcare providers should give sufficient attention to these patients and actively implement psychological interventions to enhance the psychological resilience of newly diagnosed pneumoconiosis patients,ensuring both physical and mental well-being.

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    Investigation on the allocation and utilization of radiological diagnosis and treatment resource in Dongcheng District of Beijing City
    Hongmei SHI, Sijing ZHAO, Xiang WEI, Yongzhong MA
    OCCUPATION AND HEALTH    2025, 41 (23): 3290-3294.  
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    Objective To understand the allocation and utilization of radiological diagnosis and treatment resources in Dongcheng District of Beijing City,and provide reference for the rational allocation of radiological diagnosis and treatment resources by health administrative departments. Methods Based on the Beijing radiation health monitoring information system,a general survey was conducted in all radiological diagnosis and treatment institutions(excluding military hospitals and dental clinics) in Beijing Dongcheng District from April 1,2022 to March 31,2023.The investigation convered the following aspects:The allocation of four types of radiological diagnosis and treatment equipment,namely radiodiagnosis,radiotherapy,nuclear medicine and interventional radiology,the distribution of radiological workers and the frequency data of radiological diagnosis and treatment. The number and frequency of radiological diagnosis and treatment were calculated by the total number of permanent residents by the end of 2023 in Beijing Dongcheng District. Results There were 57 hospitals equipped with radiation-generating medical devices in Beijing Dongcheng District in 2023,with an average of 7.72 devices and 24.11 staff in each hospital. The personnel and equipment configuration of tertiary medical institutions were better than those of secondary and primary medical institutions,and the difference was statistically significant(H=22.463,24.480,both P<0.01). 100.00% of the nuclear medicine equipment,81.25% of the radiotherapy equipment,and 84.85% of the interventional radiology equipment were concentrated in tertiary medical institutions,while primary and lower level institutions did not have nuclear medicine,radiation therapy,and breast X-ray detection equipment. There were 625 radiological diagnosis and treatment equipment per million population,including 78.13 CT machines,46.88 interventional radiology equipment,19.89 breast X-ray equipment,22.73 radiotherapy equipment,and 19.89 nuclear medicine related equipment. The total frequency of radiation exposure was 2 193 710,mainly focused on plain radiographs and computed tomography(CT) examinations,accounting for 41.73% and 49.70%,respectively. The annual frequency of examinations was 1 300.34 times/1 000 population and 1 548.59 times/1 000 population,respectively. The total frequency of medical radiological examinations was 3 116.07 times/1 000 population. Conclusion The application frequency of radiological diagnosis and treatment in Dongcheng District of Beijing City belongs to the level of level I healthcare,and the allocation of radiological diagnosis and treatment resources is relatively high,but the distribution is uneven in different levels of medical institutions. The health administrative department should fully utilize the advantages of medical consortia,effectively implement graded diagnosis and treatment,and improve the overall utilization rate of resources.

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    Mediating effect of team psychological safety climate on the relationship between psychological violence and job withdrawal behavior among emergency nurses in Nantong City
    Xiwen TIAN, Yixia CUI, Wen MA, Xia TIAN
    OCCUPATION AND HEALTH    2025, 41 (23): 3261-3266.  
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    Objective To understand the current situation of psychological violence,work withdrawal,and team psychological safety climate among emergency nurses in Nantong City,and to explore the mediating effect of team psychological safety climate on the relationship between psychological violence and job withdrawal behavior among emergency nurses. Methods From March to July 2024,286 emergency nurses in Nantong City were selected by convenience sampling method as research subjects. The general information questionnaires,workplace psychologically violent behaviors instrument,team psychological safety climate scale,and job withdrawal behavior scale were used for questionnaire surveys,and the data were analyzed. Results The psychological violence score of 286 emergency nurses in Nantong was (28.09±8.60)points,the team psychological safety climate score was (55.77±9.55)points,and the job withdrawal behavior score was (21.06±5.02)points. The team psychological safety climate of the emergency nursing team was negatively correlated with psychological violence and job withdrawal behavior(r=-0.412,-0.528,both P<0.01),while psychological violence was positively correlated with job withdrawal behavior(r=0.488,P<0.01). The team psychological safety climate partially mediates the relationship between psychological violence and job withdrawal behavior among emergency nurses,and the mediating effect was 0.145,accounting for 29.35% of the total effect. Conclusion Psychological violence among emergency nurses in Nantong can directly affect their job withdrawal behavior,and can also indirectly affect job withdrawal behavior through the team psychological safety climate.

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    Determination of bismuth telluride in workplace environment by graphite furnace atomic absorption spectrometry
    Eryue QU, Yu JIA, Qiang GUO, Haixia TIAN, Hang GUO, Jinhong PENG
    OCCUPATION AND HEALTH    2025, 41 (23): 3195-3200.  
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    Objective To establish a graphite furnace atomic absorption method for the determination of bismuth telluride in the workplace environment. Methods Preparation of microporous filter membrane samples using bismuth telluride standard material. After treatment,palladium nitrate and magnesium nitrate were used as matrix modifiers for graphite furnace atomic absorption spectroscopy to measure bismuth atomic content and calculate bismuth telluride. Results The linear relationship between 0-100 μg/L was good,the correlation coefficient(r) was 0.999 3,and the detection limit of the method was 3.252 μg/L. Based on the collecting of 75 L of air sample,the minimum detection concentration was 0.83 μg/m3,the recovery rate was 96.8% to 103.2%,the relative standard deviation was less than 5% and the sample can be stored for at least 7 days under sealed conditions at room temperature. Conclusion This method uses low toxicity bismuth instead of toxic tellurium for detection to reduce the risk of poisoning for experimental personnel,avoid interference from coexisting tellurides in the sampling site,and does not require the use of expensive inductively coupled plasma emission spectrometers,making it easy to popularize and apply. This method has a small sample requirement,low detection limit,sensitivity and accuracy that meet methodological requirements,the instrument has a high degree of automation,and the operation is simple,which can be used for the detection of bismuth telluride in the workplace environment.

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    Development of a whole-genome sequencing method of human coronavirus OC43 in clinical samples based on amplicon sequencing technology
    Yuqing ZHOU, Yujia HUO, Lu ZHANG, Xuechun ZHANG, Xiao WANG, Bing ZHAO
    OCCUPATION AND HEALTH    2025, 41 (23): 3200-3208.  
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    Objective To develop an efficient sequencing method for directly obtaining the whole-genome sequence of human coronavirus OC43(HCoV-OC43) from clinical samples,providing a critical technical means for genome sequencing and phylogenetic analysis of HCoV-OC43. Methods Specific primers were designed for different subtypes of HCoV-OC43 by using amplicon-based sequencing technology,patch primers were further optimized to compensate for missing regions,enabling the amplification of two overlapping segments to reconstruct the full genome sequence,and quality control was performed on both primers and sequencing data. Additionally,the effects of different amplification reaction systems and viral loads on amplification efficiency and sequencing quality were compared. Results The established method efficiently retrieved whole-genome sequences of HCoV-OC43,achieving genome coverage ≥98% and an average sequencing depth of ≥1 500×,with high specificity and sensitivity. Among 41 HCoV-OC43-positive clinical samples,31 genome sequences were successfully obtained,including 22 whole-genome sequences,8 N gene sequences,and 1 S gene sequence. Phylogenetic analysis revealed discrepancies between classifications based on different sequence fragments. Conclusion The proposed sequencing method is suitable for obtaining whole-genome sequences from HCoV-OC43-positive clinical samples with Ct values <32,which provides technical support and scientific data for molecular surveillance and the prevention and control of respiratory viruses.

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    Study on the status quo and influencing factors of health emergency response capacity of emergency responders in primary disease control and prevention institutions in Tianjin after natural disasters
    Chunxi FAN, Ning ZHOU, Ying ZHANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3226-3230.  
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    Objective To understand the current status and influencing factors of the health emergency response capacity of emergency responders in primary disease control and prevention institutions(CDC) in Tianjin after natural disasters,so as to make suggestions for the improvement of emergency response capacity. Methods From July to September 2024,a convenience sampling method was used to select 955 emergency personnel from CDC in 16 districts of Tianjin for a questionnaire survey to understand their emergency response capabilities after natural disasters,and the data were analyzed. Results The overall score of the emergency response ability of 955 emergency responders from primary CDC in each district of Tianjin was (83.26±19.42)points. The number of times participating in natural disaster emergency response capacity training,the number of times participating in natural disaster emergency response exercises,and whether or not they had experience in on-site investigation and disposal were the main influencing factors of the health emergency response capacity of emergency responders from primary CDC in Tianjin after natural disasters(all P<0.05). Conclusion The post-disaster health emergency response capacity of emergency personnel for natural disasters should be improved by increasing the intensity of natural disaster health emergency response capacity training and drills.

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    Mediating effect of self-efficacy among telecommunications industry employees between perceived stress and job burnout
    WU Xueyi, LI Wanyu, LIU Ruihong, XU Xinqing, SHAO Jiangang, JIA Liping
    OCCUPATION AND HEALTH    2025, 41 (4): 442-447.  
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    Objective To investigate the influence of perceived stress on job burnout among telecommunications employees and the role of self-efficacy and job nature in the relationship between the two. Methods From July to August 2023,a survey was conducted on 34 816 telecommunications industry employees in some provinces,municipalities and autonomous regions using the stress perception scale,general perceived self-efficacy scale,and Maslach burnout inventory,and the data were analyzed. Results The perceived stress score of telecommunications industry employees was (38.22±8.21)points,job burnout score was (34.64±15.37)points,and self-efficacy score was (26.66±7.31)points. Perceived stress scores were positively correlated with job burnout scores among telecommunications employees( r=0.732, P<0.01),while self-efficacy scores were negatively correlated with perceived stress scores and job burnout scores( r=-0.407,-0.419,both P<0.01). Self-efficacy played a partial mediating role in the impact of perceived stress on job burnout,with the mediating effect accounting for 8.206% of the total effect value,and job nature played a moderating role between self-efficacy and job burnout( β=0.029, P<0.01). Conclusion Perceived stress not only directly and positively predicts job burnout among employees in the telecommunications industry,but also has an impact on them through the mediating effect of self-efficacy,which is moderated by the job nature.
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    Effect of curcumin on endometrial epithelial cells transdifferentiation and activation of AKT/GSK-3β/β-catenin pathway induced by AngⅡ
    DONG Jing, SONG Lihua, DONG Yongjie, LI Zhiying, SONG Yujie, LI Ling
    OCCUPATION AND HEALTH    2025, 41 (4): 458-462.  
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    Objective To analyze the effects of curcumin on the proliferation,secretion,transdifferentiation ability,and activation ofprotein kinase B(AKT)/glycogen synthase kinase-3β(GSK-3β)/β-catenin pathway in endometrial epithelial cells(EECs) induced by angiotensinⅡ(Ang Ⅱ),and exploring the protective mechanism of curcumin on endometrial fibrosis. Methods Primary human EECs were separated and identified,and were divided into four groups based on different treatment methods:normal group,curcumin group,AngⅡgroup,and curcumin treatment group.Normal group:conventional incubation solution,curcumin group:incubation solution containing curcumin(30 μmol/L),AngⅡ group:incubation solution containing AngⅡ(10 -6 mol/L),curcumin treatment group:incubation solution containing AngⅡ(10 -6 mol/L) and curcumin(30 μmol/L),each group was treated for 48 hours.The proliferation status of each group of cells was compared,and the secretion levels of type I and Ⅲ collagen in the cell culture medium were analyzed. Western blot was used to detect the protein expression level such as cell differentiation marker molecules E-cadherin and alpha smooth muscle actin(α-SMA),AKT/GSK-3β/β-Catenin pathway molecules phosphorylated protein kinase B(p-AKT),phosphorylated glycogen synthase kinase-3β(p-GSK-3β) and β-catenin. Results There were no statistically significant differences in cell proliferation,secretion of typeⅠand Ⅲ collagen in the incubation solution,expression levels of transdifferentiation molecules,and AKT/GSK-3β/β-catenin pathway molecules between the DHA group and the normal group(all P>0.05).Compared with the normal group,the AngⅡgroup showed an increase in cell number(0.122±0.002),secretion of type I collagen(0.538±0.093) and typeⅢcollagen(0.492±0.097),as well as an increase in the expression level of transdifferen tiation marker molecules a-SMA(0.492±0.031),AKT/GSK-3β/β-catenin pathway molecules p-AKT(1.119±0.064),p-GSK-3β(0.904±0.057),and β-catenin(0.121±0.002)(all P<0.05),while the expression level of E-Cad(0.349±0.021) decreased( P<0.05).Compared with the AngⅡ group,the curcumin treatment group showed a decrease in cell number(0.118±0.001),a decreased in secretion of type I collagen(0.348±0.063) and typeⅢcollagen(0.306±0.063),a decrease in the expression level of transdifferentiationmarker molecules a-SMA(0.221±0.015),AKT/GSK-3β/β-catenin pathway molecules p-AKT(0.705±0.052),p-GSK-3β(0.563±0.029),and β-catenin(1.106±0.070)(all P<0.05),while the expression level of E-Cad(0.661±0.024) increased( P<0.05). Conclusion Curcumin can regulate AKT/GSK-3β/β-catenin pathway and inhibit EECs proliferation,secretion,and transdifferentiation induced by AngⅡ.
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    Determination of 8 aryloxyphenoxypropionate herbicides in bean products by QuEChERS coupled with HPLC-MS/MS
    ZHAO Wei, TIAN Huifang, CHEN Longxing, LI Lu, NIU Wendan, GUO Aijing
    OCCUPATION AND HEALTH    2025, 41 (4): 463-466.  
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    Objective To establish a QuEChERS coupled with high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS) method for determination of 8 aryloxyphenoxypropionate herbicides in bean products. Methods The samples were extracted with acetonitrile,purified with N-primary secondary amine(PSA) and anhydrous MgSO 4,separated with a Poroshell 120 EC-C 18 column,and detected with an alternate positive/negative ion electro spray ionization(ESI) mode under multiple reaction monitoring. External standard calibration curves were used for quantitative analysis. Results A good linear relationship between quizalofop-ethyl and propaquizafo in the range of 0.50-200.00 ng/mL,and the other six aryloxyphenoxypropionate herbicides in the range of 0.20-200.00 ng/mL,with a correlation coefficient of ≥0.999,limits of detectionof 0.01-1.26 μg/kg,and limits of quantification of 0.03-4.20 μg/kg. The average recoveries were 70.52%-100.03% with relative standard deviations( RSD) of 0.76%-9.28% at the spiked levels of 5,10,50 μg/kg. Conclusion The established method is simple,quick and sensitive,and accurate in both qualitative and quantitative analysis. It is suitable for the detection of 8 types of aryloxyphenoxypropionate herbicides in bean products.
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    Analysis on detection results of volatile organic compounds in the air of some employers' workplaces in Chongqing in 2023
    YANG Leilei, YANG Lianwei, ZHANG Tengtao
    OCCUPATION AND HEALTH    2025, 41 (4): 448-452.  
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    Objective To understand the concentration and hazards of eight volatile organic compounds(VOCs) in the air of employer's workplace using organic solvents in a certain district of Chongqing,and to provide scientific evidence for employers to carry out the prevention and treatment of occupational diseases. Methods According to the requirements of relevant national standards,air samples were taken from 18 workplaces of employers in Chongqing,the benzene,toluene,xylene,ethylbenzene,chloroform,trichloroethylene,1,2-dichloroethane and n-hexane were detected by solvent desorption-gas chromatography,and the detection results were analyzed. Results There were a total of 51 positions with a VOCs over-standard rate of 29.41%. Out of 255 samples,the VOCs detection rate was 67.84%. The hazardous factors that exceed the standard included benzene,xylene and 1,2-dichloroethane,with over-standard rate of 9.80%,7.84%,and 21.57%,respectively. The over-standard rate and over-standard multiple of 1,2-dichloroethane were the highest,exceeding the limit by 34.87 times. The exceedance positions were all distributed in small enterprises. Conclusion The hazards of benzene,xylene and 1,2-dichloroethane were serious in workplace of employers in a certain district of Chongqing. Employers should take targeted protective measures according to the excessive situation of VOCs to control the concentration of VOCs in the air in the workplace and protect the health of workers.
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    Investigation on occupational stress status among production workers in a chemical drug preparation manufacturing enterprise in Chongqing
    ZHANG Li, WANG Yun, PENG Zhongquan, TIAN Ping, XIE Xiaotong
    OCCUPATION AND HEALTH    2025, 41 (4): 433-436.  
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    Objective To analysis the current situation of occupational stress among production workers in a chemical drug preparation manufacturing enterprise in Chongqing,so as to provide reference for improving occupational stress intervention work in the enterprise. Methods A survey was conducted on all production workers who participated in occupational health examinations during their employment in a chemical drug manufacturing enterprise in Chongqing in 2023. The occupational stress inventory-revised edition(OSI-R) was used to conduct an online questionnaire survey,and the survey data were analyzed. Results The scores of occupational task questionnaire and personal stress response questionnaire for 224 production workers included in the survey were (133.72±23.69) and (79.32±19.24)points,respectively,which were significantly lower than the norm group in southwest China(both P<0.01). The score of the personal adaptability questionnaire for production workers was (130.58±18.25) points,with no statistically significant difference compared to the norm( P>0.05),but the scores for social support and rational handling dimensions were lower than the norm(both P<0.05). The incidence rates of moderate or above occupational task stress,moderate or above stress response,and moderate or above lack of adaptability among production workers were 1.79%,7.14% and 12.95%,respectively. The occupational task stress questionnaire scores of male workers were higher than female workers,and the personal stress response questionnaire scores of workers unmarried and owning bachelor degree or above were respectively higher than workers married and owning college degree or below,and the differences were all statistically significant(all P<0.05). Conclusion The overall situation of occupational stress among production workers in a chemical drug preparation manufacturing enterprise is at a good level. Occupational stress intervention should focus on male,unmarried and highly educated workers. By strengthening social support and providing workers with resources,guidance and assistance to improve workers' ability of controlling own emotion and coping with occupational stress.
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    Effect of curcuminon improving cognitive function and depressive like behavior in sleep deprived mice by regulating autophagy
    SUN Tingting, WANG Congmin, DONG Jing, SHAN Tieqiang, SONG Yajuan, QI Jiao
    OCCUPATION AND HEALTH    2025, 41 (2): 177-180.  
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    Objective To analyze the effects of curcumin on learning and memory ability,depressive like behavior,and autophagy proteins,phosphatidylinositol 3 kinase(PI3K)/serine kinase(AKT) pathway proteins in hippocampal tissue in sleep deprived mice,and to explore the mechanism of curcumin antagonizing cognitive function and depressive like behavior induced by sleep deprivation. Methods A sleep deprived mouse model was prepared using the "improved platform water environment" method,and the experiment was arranged into a normal control group,a sleep deprivation group and a curcumin group. The curcumin group were injected intraperitoneally with 10 and 20 mg/kg curcumin,respectively,while the normal control group and sleep deprivation group were injected intraperitoneally with an equal volume of 0.9% sodium chloride. Once daily for 7 days. The water maze experiment was used to measure the cognitive function of mice in each group. The open box experiment and sugar water preference experiment were used to evaluate the depression like behavior of mice in each group. Western blotting was used to analyze the content of autophagic proteins Bcl-2 homologous domain protein antibody(Beclin 1),microtubule associated protein light chain 3II(LC3II)/microtubule associated protein light chain 3I(LC3I) in hippocampal tissue,as well as the content of phosphorylated phosphoinositol 3-kinase(p-PI3K)/PI3K and phosphorylated serine kinase(p-AKT)/AKT autophagic proteins. Results Compared with the normal control group,the escape latency[(43.79±6.17)s] of sleep deprived mice was prolonged,and the number of crossing platforms[(10.48±1.28)times] was reduced(both P<0.01),the number of crossing score(53.27±7.99),the number of crossing score(45.63±6.56),and the preference rate for sugar water[(32.61±4.97)%] all decreased(all P<0.01),the levels of Beclin 1(1.58±0.16) and LC3II/LC3I (1.21±0.16) in hippocampal tissue increased(both P<0.01),while the levels of p-PI3K/PI3K(0.26±0.03) and p-AKT/AKT(0.40±0.05) decreased(both P<0.01). Compared with the sleep deprivation group,the curcumin group had a shorter escape latency[(31.89±3.81,27.01±3.41)s] and an increased number of crossing platforms[(16.57±1.90,20.26±2.55)times](all P<0.01),the number of crossing score(95.39±13.88,114.76±14.94),rearing score(74.32±7.99, 86.25±9.42) and preference rate for sugar water[(43.09±5.46,51.89±7.38)%] all increased(all P<0.01),the levels of Beclin 1(1.07±0.11,0.92±0.10) and LC3II/LC3I(0.89±0.11,0.72±0.11) in hippocampal tissue decreased(all P<0.01),while the levels of p-PI3K/PI3K(0.51±0.06,0.61±0.06) and p-AKT/AKT(0.59±0.06,0.68±0.07) increased(all P<0.01),and showed a dose-dependent relationship. Conclusion Curcumin can improve cognitive function and alleviate depressive like behavior in sleep deprived mice,which is closely related to its activation of the PI3K/AKT pathway and inhibition of hippocampal autophagy.
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    Meta-analysis of factors influencing sleep disorders among Chinese college students
    ZHONG Zhongci, BIAN Jia, HU Xinlan, QIU Xiaoqiao, ZHAO Zhuang, DONG Lijuan
    OCCUPATION AND HEALTH    2025, 41 (4): 547-553.  
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    Objective To explore the influencing factors of sleep disorders among college students in China,and to provide reference basis for the prevention and intervention of sleep disorders among Chinese college students. Methods Relevant studies on the prevalence of sleep disorders among Chinese college students were searched in Wanfang Database,China Biomedical Literature Service System,China National Knowledge Infrastructure(CNKI),VIP Database,PubMed,Web of Science,Embase,Cochrane,etc. from January 2015 to March 2024. Two researchers independently screened the literature,extracted information and evaluated the quality of the included literature.Rev Man 5.4 software was used for meta-analysis of the included literature. Results A total of 48 articles were included,with a total sample size of 81 472 cases,and 15 relevant influencing factors were extracted.The meta-analysis results showed that depression( OR=272,95% CI:1.72-4.30, P<0.01),pressure to choose a job( OR=1.38,95% CI:1.11-1.71, P<0.01),sleep environment( OR=1.79,95% CI:1.33-2.41, P<0.01),electronic products( OR=1.70,95% CI :1.30-2.28, P <0.01),interpersonal relationship( OR =1.43,95% CI :1.19-1.72, P <0.01),senior grade( OR =1.24,95% CI :1.03-1.48, P <0.01),economic status( OR =1.21,95% CI :1.03-1.43, P <0.01),emotional problems( OR =2.15,95% CI :1.43-3.22, P <0.01),major(medical students)( OR =1.66,95% CI :1.22-2.24, P <0.01),anxiety( OR =1.82,95% CI :1.44-2.31, P <0.01),physical condition( OR =1.92,95% CI :1.56-2.37, P <0.01),gender(female)( OR =1.25,95% CI :1.17-1.33, P <0.01),physical exercise( OR =0.83, 95% CI :0.78-0.89, P <0.01),regular work and rest( OR =2.22,95% CI :1.92-2.57, P <0.01),and academic pressure( OR =1.76,95% CI :1.43-2.17, P <0.01) were the influencing factors of sleep disorders among college students in China. Conclusion Depression,career choice pressure,sleep environment,use of electronic products,interpersonal relationships,senior grades,economic status,emotional problems,major(medical students),anxiety,physical condition,gender(female),and academic pressure are risk factors for sleep disorders in college students. Regular physical exercise and regular work and rest schedules are protective factors for sleep disorders in college students. Colleges and universities and related departments can pay great attention to the above factors and do early prevention work to improve the sleep quality of college students.
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    Impact of boundary flexibility and work-family conflict on work-family balance of obstetrics and gynecology nurses
    Lujing WANG, Jianying LUO, Hua ZHUANG, Qiaoying YAO, Lan QU, Huihui HU
    OCCUPATION AND HEALTH    2025, 41 (23): 3214-3218.  
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    Objective To investigate the current status of boundary flexibility,work-family conflict and work-family balance of obstetrics and gynecology nurses,and to analyze the impact of boundary flexibility and work-family conflict on work-family balance. Methods From September to October 2024,184 obstetrics and gynecology nurses from 9 grade-A tertiary hospitals in Shanghai were selected as the survey subjects by simple random sampling. The boundary flexibility scale,work-family conflict scale and work-family balance scale were used to evaluate the impact of boundary elasticity and work-family conflict on work family-balance levels. Pearson correlation analysis was used to analyze the correlation between boundary elasticity,work-family conflict,and work-family balance among obstetrics and gynecology nurses. The mediation effect test method was used to analyze the mediating effect of work-family conflict on the boundary elasticity and work-family balance of obstetrics and gynecology nurses. Results The boundary flexibility score of obstetrics and gynecology nurses was (48.33±8.84)points,the work-family conflict score was (52.48±9.64)points,and the work-family balance score was (55.86±9.37)points. The influencing factors of work-family balance of obstetrics and gynecology nurses were age,years of work experience,professional title,marital status,average monthly income,and average number of night shifts per month(all P<0.05). There was a positive correlation between boundary flexibility and work-family balance among obstetric and gynecological nurses(r=0.608,P<0.01),a negative correlation between work-family conflict and work-family balance(r=-0.542,P<0.01),and a negative correlation between boundary flexibility and work-family conflict(r= -0.584,P<0.01). Work-family conflict played a partial mediating role between boundary flexibility and work-family balance among obstetric and gynecological nurses,with a mediating effect value of 0.254,accounting for 42.55% of the total effect. Conclusion Work-family conflict played a partial mediating role between boundary flexibility and work-family balance among obstetric and gynecological nurses. Improving the level of boundary flexibility of obstetric and gynecological nurses and reducing their level of work-family conflict are conducive to improving their work-family balance.

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    Analysis of low background α and β radiation in surface and underground drinking water in Qiqihar City
    Tiejun SHE, Jing ZHANG, Huanan DU, Lei ZHANG, Wensu FAN, Jiao WANG
    OCCUPATION AND HEALTH    2025, 41 (23): 3267-3271.  
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    Objective To understand the activity of total α and β radiation in surface and groundwater in Qiqihar City,and to analyze the overall water quality situation,so as to achieve long-term monitoring and early warning,and ensure water safety for residents. Methods In the dry season from January to March and the wet season from June to August in 2024,the surface water and groundwater were collected respectively. The water samples were acidified,concentrated,charred,ashes,ground and coated,and compared with the standard materials. The dual-channel FYFS-400X low background α and β measuring instrument was used for analysis. Results A total of 162 water samples were collected from 27 sampling sites in Qiqihar City,and the total α and β activity concentrations ranged from 0.016-0.086 and 0.050-0.182 Bq/L,respectively. Among them,the share of Class Ⅰ water sources was 42.9%,and the share of Class Ⅱ water sources was 57.1%. Conclusion In 2024,the total α and β radioactivity of the water samples of Nenjiang River,Namur River,Uyur River,Yaru River and 15 water plants in Qiqihar City meet the relevant requirements,and meet the standards for drinking water.

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    Analysis on impact of work-family role conflict and role overload on job burnout of orthopedic nurses
    MA Lan, GUO Xiajing, SONG Honghong, YANG Jie, WU Jia, SUN Yanni
    OCCUPATION AND HEALTH    2025, 41 (12): 1590-1594.  
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    Objective To investigate the status of work-family role conflict,role overload and occupational burnout of orthopedic nurses,analyze the impact of work-family role conflict and role overload on occupational burnout of orthopedic nurses. Methods Using the random number table method,174 orthopedic nurses from 10 tertiary hospitals in Shanxi Province were selected from June to December 2023 as the research subjects. The work-family role conflict scale,role overload scale and occupational burnout scale were respectively used to investigate the levels of work-family role conflict,role overload and occupational burnout. Results The scores of work-family role conflict,role overload and occupational burnout of orthopedic nurses were (63.24±12.25),(18.64±3.72) and (60.53±8.47)points,respectively. There were statistically significant differences in job burnout scores among orthopedic nurses of different age,years of work experience,professional title,marital status,average monthly income,average number of night shifts per month,and number of raised children(all P<0.05). The job burnout of orthopedic nurses was positively correlated with work-family role conflict and role overload( r=0.684,0.642,both P<0.01),and role overload was positively correlated with work-family role( r=0.586, P<0.01). The work-family role conflict and role overload could jointly explain 31.70% of the variance of job burnout of orthopedic nurses. Conclusion The work-family role conflict,role overload and occupational burnout of orthopedic nurses are at a high level,both work-family role conflict and role overload are positively correlated with job burnout,and reducing the level of work-family role conflict and role overload is conducive to reducing the level of job burnout.
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    Simultaneous determination of eight herbicides and plant growth regulators in drinking water by ion chromatography
    MA Xiaoman, SHI Hongmei, LI Yunbing, ZHANG Laiying, GAO Lihong, WANG Yujiang
    OCCUPATION AND HEALTH    2025, 41 (12): 1625-1629.  
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    Objective To develop a detection method for simultaneous determination of eight herbicides(including 2,4-D,fosamine,aminomethylphosphonic acid,glufosinate,ethephon,glyphosate,glyphosine,and bentazone) and plant growth regulators in drinking water by ion chromatography,which has a simple pretreatment process and only requires common reagents. Methods The water sample is sequentially filtered through a 0.2 μm microporous membrane and a Ba/Ag/H cartridge before being introduced into the system. The effective separation is achieved on an IonPac AS19 chromatographic column using a 2-60 mmol/L potassium hydroxide gradient elution program. After the background signal is reduced by a suppressor,the analytes are detected by a conductivity detector. Results The eight analytes exhibit excellent linearity within the concentration range of 0.002-0.200 mg/L(0.005-0.200mg/L),with correlation coefficients( r) all >0.999. The method demonstrates detection limits ranging 0.000 2-0.003 6 mg/L and quantification limits ranging 0.000 6-0.011 1 mg/L. At low,medium,and high spiked concentration levels,the recovery rates range from 94.3% to 108.6%,with relative standard deviations( RSD) between 0.592% and 4.425%( n=7). Compared with the national standard method,the detection results showed no statistically significant difference( P>0.05). Conclusion This method is characterized by its simplicity of operation,effective separation,and satisfactory accuracy,precision and sensitivity,making it suitable for routine monitoring of drinking water.
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    Systematic evaluation of the influencing factors and injury characteristics of military training injuries in high-altitude troops
    XIAO Chulan, LI Junhui, GUO Yiting, LI Fuqiang, DU Yangyang, ZHANG Hua
    OCCUPATION AND HEALTH    2025, 41 (12): 1690-1696.  
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    Objective Based on the investigation and analysis of military training injuries(MTI) in high-altitude troops,this study aims to explore the influencing factors and injury characteristics,in order to provide reference for future related investigations and research as well as the prevention and treatment of MTI in high-altitude troops. Method Review Manager 5.3 software was used to organize and analyze the relevant investigation and research on MTI of high-altitude troops in China National Knowledge Infrastructure(CNKI),VIP,and Wanfang databases. The retrieval time was from the establishment of the database to February 2024. A systematic evaluation was conducted based on different influencing factors and injury characteristics. Results A total of 27 articles were included,with a total of 14 766 cases of MTI. Meta-analysis results showed that the combined incidence of MTI was 19%. The results of subgroup analysis of various influencing factors showed that the incidence rate of cadres( RD=0.14, 95% CI:-0.18-0.46) was lower than that of conscripts( RD=0.22,95% CI:-0.18-0.62) and non-commissioned officers( RD=0.23,95% CI:0.17-0.63),the incidence rate of military sources in cities( RD=0.17,95% CI:-0.35-0.68) was lower than that in rural areas ( RD=0.22,95% CI:-0.34-0.78),the incidence of college degree and below( RD=0.30,95% CI:-0.19-0.78)was higher than undergraduate and above( RD=0.17,95% CI:-0.30-0.63),the incidence rate was highest at an altitude of 3 000-<4 000 m( RD=0.23,95% CI:-0.00-0.47),followed by≥4 000 m( RD=0.18,95% CI:-0.18-0.54) and 2 000-<3 000 m( RD=0.09,95% CI:-0.31-0.49). The highest incidence rate was observed in 2016-2024( RD=0.25,95% CI:-0.08-0.57),followed by before 2005( RD=0.17,95% CI:-0.06-0.39) and 2006-2015( RD=0.16,95% CI:-0.07-0.39). There was no statistically significant difference in age and body mass index(BMI) between the MTI group and the normal group(both P>0.05),and warm-up before training was a factor affecting MTI( P<0.05). The highest proportion of injury sites was in the upper limbs,followed by the trunk,lower limbs,and head and neck. The highest proportion of injury types was soft tissue injury,followed by bone and joint injury,other injuries,and organ injury. In recent years,the proportion of soft tissue injury had gradually increased,while other injuries had relatively decreased. The highest proportion of injury training was physical training,followed by professional technical training,tactical training,and other common subjects. The highest proportion of injury causing factors was found in group training factors,followed by individual factors and environmental factors. Conclusion There are many influencing factors for MTI of officers and soldiers at high altitude,among which warm-up before training can effectively prevent their occurrence,and the prevalence rate of compulsory soldiers,college education,rural soldiers,Xizang and other regions,high training intensity is higher. In addition,the site of injury is concentrated in the upper limbs,with soft tissue injury as the main type of injury. The injury training is mostly physical training,and the injury factors are mostly group training factors.
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    Research progress on micro-aggressions in medical staff
    LIU Jinyi, WANG Yuting, XU Shuiqin
    OCCUPATION AND HEALTH    2025, 41 (12): 1702-1706.  
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    As medical staff are the providers of medical services,effective prevention and measures of micro-aggressions from patients is important to maintain the physical and mental health of medical personnel,improve the patient's medical experience and establish the new relationship between the doctors and the patients.The research on micro-aggressions of medical staff in foreign countries includes training medical personnel in micro-aggressions education,creating micro-aggressions education tools,development of behavior frameworks,while the research on micro-aggressions in China is confined to the discussion in the field of education and still in the initial stage. This paper reviews the concept,current situation,assessment tools,influencing factors and interventions of micro-aggressions in medical staff,in order to provide a reference for formulating an intervention program adapted to the micro-aggressions of medical personnel in China.
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    Research progress on application of exercise intervention in elderly individuals with cognitive frailty
    CHANG Qihang, BU Haoning, ZHANG Shuyong, LI Wentao
    OCCUPATION AND HEALTH    2025, 41 (12): 1724-1728.  
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    The cognitive frailty refers to a heterogeneous clinical syndrome where physical frailty and cognitive dysfunction coexist,excluding Alzheimer's disease and other types of dementia,and it can increase the risk of adverse health outcomes such as falls,hospitalization,and death in the elderly. The cognitive frailty typically occurs in older populations and poses a serious threat to their health. In recent years,cognitive frailty has increasingly gained the attention of scholars. This article provides a comprehensive review of the methods of exercise intervention on cognitive frailty and their application effects in the elderly population with cognitive frailty,aiming to provide a reference for the implementation of exercise intervention strategies in the elderly with cognitive frailty in the future.
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    Investigation on current situation of occupational hazards in manufacturing industry in Haicang District of Xiamen City
    WU Xiaojun, XIE Shirong, WEN Jianping, GAN Hongfang, ZEN Jinshui
    OCCUPATION AND HEALTH    2025, 41 (2): 145-149.  
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    Objective To conduct an occupational hazard survey on 268 manufacturing enterprises in Haicang District of Xiamen City,in order to understand and grasp the distribution of occupational hazards and the current status of occupational health management,and provide a basis for further special treatment of occupational hazards. Methods From February to May 2022,field investigation were conducted on enterprises in Haicang District to investigate their basic information,exposure to occupational hazards,and occupational health management,and the data were analyzed. Results A total of 21 459 employees in 268 manufacturing enterprises were exposed to occupational hazards,with an occupational hazard exposure rate of 20.39%. The dust exposure rate of employees was 7.04%,the chemical exposure rate was 5.64%,and the physical exposure rate was 12.65%. Among them,noise was the hazard factor with the highest number of enterprises and people affected.Employees exposed to occupational hazard factors were mainly concentrated in medium-sized enterprises,rubber and plastic products industry,computer,communication and other electronic equipment manufacturing,metal manufacturing and other industries,and there was a statistically significant difference in the exposure rate of occupational hazards among employees in different industries and enterprises of different scales(both P<0.01).The rates of occupational health training for the principal person in charge,occupational health management personnel and employees were 98.51%,98.51% and 97.39%,respectively,and the rate of regular detection of occupational disease hazard factors was 97.01%.The occupational health examination rate for employees during their employment was 85.82%.The occupational health examination rate of employees showed an increasing trend with the scale of the enterprise from small to large( P<0.01). Conclusion The focus of occupational health management in Haicang District of Xiamen City is on small and micro enterprises,especially micro enterprises. It is necessary to implement targeted supervision in key industries based on the exposure situation,and do a good job in the prevention of physical harmful factors including noise. Strengthen supervision and law enforcement efforts,urge enterprises to do a good job in occupational health examinations,and safeguard the health rights and interests of employees.
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    Analysis of occupational health examination results for key occupational disease monitoring occupational population in Cangzhou City from 2018 to 2022
    HAN Yu, SUN Hongxuan, ZHANG Xia, ZHAO Xiaona, LU Yinglian, LAN Yanfang
    OCCUPATION AND HEALTH    2025, 41 (2): 150-155.  
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    Objective To analyze the monitoring results of key occupational diseases in Cangzhou City from 2018 to 2022,further grasp the health status of laborers,and provide technical basis for formulating occupational disease prevention and control strategies in Cangzhou City. Methods The monitoring data of key occupational diseases and occupational health examinations in Cangzhou City from 2018 to 2022 were collected,and a database was established with Excel 2016.Data were sorted and analyzed with SPSS 21.0 software. Results The number of monitored occupational diseases and the number of occupational health examinations in Cangzhou City increased year by year from 2018 to 2022.A total of 9 cases of occupational disease were reported in the past 5 years,mostly distributed in private small enterprises,and most of them were men,most of the working years were less than 3 years.In the past five years,a total of 802 cases of occupational contraindications were detected,accounting for 0.38%,and 22 cases of suspected occupational diseases were reported,accounting for 0.01%,among which 13 cases were suspected noise deafness.In the past five years,the occupational health examinations in Cangzhou City was mainly concentrated in small private enterprises,with a focus on males,and the age was concentrated between 30 and 40 years old. The occupational health examination results of workers exposed to benzene derivatives in Cangzhou City from 2018 to 2022 showed that the detection rate of abnormal blood routine was 4.79%. The differences in abnormal blood routine rates among employees of different genders,ages,enterprise sizes,and economic types were statistically significant(all P<0.05).The occupational health examination results of workers exposed to noise showed that the abnormal detection rate of hearing screening was 5.19%,and there were statistical differences in the abnormal rate of hearing screening according to gender,age,enterprise scale and economic type(all P<0.05).The abnormal rate of hearing screening showed a trend change with the change of age and enterprise scale,and the difference were statistically significant( χ 2=1 857.92,487.405,both P<0.01).The occupational health examination results of workers exposed to dust showed that the detection rate of abnormal lung function was 5.21%,and there were statistical differences in the detection rate of abnormal lung function among different gender,age,enterprise scale and economic type(all P<0.05).The detection rate of abnormal lung function showed a trend change with the change of age and enterprise scale,and the differences were statistically significant( χ 2=500.269,514.794,both P<0.01). Conclusion The prevention and treatment of occupational diseases in Cangzhou City should focus on the prevention and treatment of occupational hazards such as benzene,noise,dust and other occupational hazards,strengthen the supervision of Hong Kong,Macao and Taiwan enterprises,small and medium-sized enterprises,and enhance the awareness of legal responsibility and social responsibility of employers. Strengthen the supervision and training of the occupational health inspection institutions and improve the ability of occupational health examinations,strengthen the training and protection of workers,expand publicity and education,enhance workers' knowledge of occupational disease prevention and treatment supervise the use of protective equipment,and reduce the occurrence of occupational diseases.
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